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Anti-MTHFR Antibody (R3K99)

Catalog #:   RHE38502 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG1
Applications: ELISA, IHC, WB
Accession: P42898
Overview

Catalog No.

RHE38502

Species reactivity

Human, Rat

Host species

Mouse

Isotype

IgG1

Clonality

Monoclonal

Tested applications

ELISA: 1:10000, IHC: 1:200-1:1000, WB: 1:500-1:2000

Target

Methylenetetrahydrofolate reductase, MTHFR

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P42898

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R3K99

Data Image
  • Immunohistochemical
    Immunohistochemical analysis of paraffin-embedded human lung cancer using MTHFR mouse mAb with DAB staining.
  • Immunohistochemical
    Immunohistochemical analysis of paraffin-embedded human intima cancer tissues (left) and prostate tissues (right) using MTHFR mouse mAb with DAB staining.
  • Western blot
    Western blot analysis using MTHFR mouse mAb against Rat Heart cell lysate.
References

Study of the MTHFR 677C>T Polymorphism in Children and Adolescents with Hashimoto's Thyroiditis: An Original Case-Control Study., PMID:40506882

Timing of diagnostic workups in Chinese population with recurrent pregnancy loss: a cross-sectional study., PMID:40158174

Avascular Necrosis of the Femoral Head in Patients with Antiphospholipid Syndrome: A Case Series., PMID:40126224

Recurrent Early Pregnancy Loss and Congenital Thrombophilia: A Prospective Study., PMID:39598015

MTHFR polymorphisms and vitamin B12 deficiency: correlation between mthfr polymorphisms and clinical and laboratory findings., PMID:39196375

Multi-Gene Single Nucleotide Polymorphism Detection in Gastric Cancer Based on Ion Semiconductor Sequencing Platform., PMID:38801272

Combination of 15q24 Microdeletion Syndrome and Metabolic Imbalance in a Patient with Atypical Autism., PMID:38180598

Interplay between carotid artery dissection and thrombophilia leading to ischaemic stroke after minor head trauma in an adolescent: a case report., PMID:37849317

Evaluation of acquired and hereditary risk factors for the development of thromboembolism in patients with systemic lupus erythematosus., PMID:37756208

Prothrombotic states in portal vein thrombosis and Budd-Chiari syndrome in India: A systematic review and meta-analysis., PMID:37610562

Endothelial dysfunction, thrombophilia, and nailfold capillaroscopic features in livedoid vasculopathy., PMID:37543163

The prognostic role of gene polymorphisms in patients with indolent non-Hodgkin lymphomas and mantle-cell lymphoma receiving bendamustine and rituximab: results of the 5-year follow-up study., PMID:37424258

MTHFR act as a potential cancer biomarker in immune checkpoints blockades, heterogeneity, tumor microenvironment and immune infiltration., PMID:37354330

Chronic Suppurative Otitis Media Patient Presenting With Hyperhomocysteinemia in Granulomatosis With Polyangiitis., PMID:37273400

Dermatological Manifestations in COVID-19: A Case Study of SARS-CoV-2 Infection in a Genetic Thrombophilic Patient with Mthfr Mutation., PMID:36986360

Diagnostic factors for recurrent pregnancy loss: an expanded workup., PMID:36964323

The Proper Diagnosis of Thrombophilic Status in Preventing Fetal Growth Restriction., PMID:36766616

Methylenetetrahydrofolate Reductase 677T Allele Is a Risk Factor for Arterial Thrombosis in Chinese Han Patients with Antiphospholipid Syndrome., PMID:36672563

Folic acid restricts SARS-CoV-2 invasion by methylating ACE2., PMID:36060767

Migraine With Comorbid Depression: Pathogenesis, Clinical Implications, and Treatment., PMID:35865445

Absorption and Tissue Distribution of Folate Forms in Rats: Indications for Specific Folate Form Supplementation during Pregnancy., PMID:35745126

Osteoprotegerin and MTHFR gene variations in rheumatoid arthritis: association with disease susceptibility and markers of subclinical atherosclerosis., PMID:35680906

Association of ALDH2 rs671 and MTHFR rs1801133 polymorphisms with hypertension among Hakka people in Southern China., PMID:35346052

Evaluation of umbilical cord immune cells in pregnancies with autoimmune disorders and/or methylenetetrahydrofolate reductase polymorphisms., PMID:35344642

[The 492nd case: recurrent thrombosis, thrombocytopenia]., PMID:35090264

Singleton pregnancy losses before gestational week 22 among patients with autoimmune disorders and methylenetetrahydrofolate reductase polymorphisms., PMID:35001885

Folic Acid and Autism: A Systematic Review of the Current State of Knowledge., PMID:34440744

Association of increased C-Reactive Protein and hypocomplementemia with risk factors for thrombosis in women who have susceptibility for poor gestational outcome; importance of preconceptional counseling., PMID:34275896

A study of hyperhomocysteinemia in cerebral venous sinus thrombosis., PMID:34145098

Genetic Factors of Predisposition and Clinical Characteristics of Rheumatoid Arthritis in Russian Patients., PMID:34070522

Janus Kinase-2 Mutation Associated Portal Vein Thrombosis Complicating Liver Cirrhosis and Hepatocellular Carcinoma., PMID:33507708

A Association of MTHFR C677T and MTRR A66G Gene Polymorphisms with Iranian Male Infertility and Its Effect on Seminal Folate and Vitamin B12., PMID:33497043

Inherited and acquired thrombophilia in adults with retinal vascular occlusion: A systematic review and meta-analysis., PMID:32805772

Plasma Serotonin is Elevated in Adult Patients with Sudden Sensorineural Hearing Loss., PMID:32717753

DVT and Pulmonary Embolism Following Knee Arthroscopy: The Role of Genetic Predisposition and Autoimmune Antibodies: A Report of 3 Cases., PMID:32649112

Tetra-primer ARMS-PCR combined with GoldMag lateral flow assay for genotyping: simultaneous visual detection of both alleles., PMID:32350488

Immunohistochemical and genetic prognostic factors of neoadjuvant chemoradiotherapy efficаcy in personalized treatment of local advanced rectal cancer., PMID:32285840

The utility of thrombophilia testing in patients with newly diagnosed portal vein thrombosis., PMID:32101880

Thrombophilic risk factors for retinal vein occlusion., PMID:31831825

Acute ischemic stroke in a 7-month-old infant, risk factors, and diagnosis peculiarities: A case report., PMID:31725629

Thrombophilic risk factors in hemodialysis: Association with early vascular access occlusion and patient survival in long-term follow-up., PMID:31539375

Genetic contributors and soluble mediators in prediction of autoimmune comorbidity., PMID:31444033

Spontaneous pregnancies in patients with at least one failed IVF cycle after the management of autoimmune disorders, hereditary thrombophilia, and methylation disorders., PMID:31173496

Retinal vein occlusion in child with rare mutations in genes for thrombophilia., PMID:31173043

Pregnancy outcomes of the patients with anti-smooth muscle antibody positivity., PMID:30909204

Management and the pregnancy outcomes of patients positive for anti-parietal cell antibody., PMID:30594922

Study of gene polymorphisms as predictors of treatment efficacy and toxicity in patients with indolent non-hodgkin lymphomas and mantle cell lymphoma receiving bendamustine and rituximab., PMID:30203425

Comparison of two groups for the apolipoprotein E polymorphisms by using next generation sequencing: The first group with three consecutive abortions and the second group with at most one abortion in three consecutive pregnancies., PMID:29778421

Gene variants in the folate pathway are associated with increased levels of folate receptor autoantibodies., PMID:29732742

Association of MTHFR C677T and A1298C gene polymorphisms with methotrexate efficiency and toxicity in Algerian rheumatoid arthritis patients., PMID:29264421

Datasheet

Document Download

Anti-MTHFR Antibody (R3K99).pdf

 

$ 220
Product specifications
50 μg 220 100 μg 350

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Anti-MTHFR Antibody (R3K99) [RHE38502]
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