Catalog No.
RHE37709
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
ELISA: 1:10000, FCM: 1:200-1:400, IF: 1:500-1:2000
Target
p16-INK4, Multiple tumor suppressor 1, MTS-1, MTS1, Cyclin-dependent kinase 4 inhibitor A, p16-INK4a, Cyclin-dependent kinase inhibitor 2A, CDKN2A, p16INK4A, CDKN2, CDK4I
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P42771
Applications
ELISA, FCM, IF
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3K97
ctDNA Analysis in ERBB2-Amplified Colorectal Cancer: Biomarker Analysis of the MyPathway Trial., PMID:40512191
Biological and Clinical Relevance of Genetic Alterations in Peripheral T-cell Lymphomas., PMID:40416001
Molecular Mechanisms of Tumor Progression and Novel Therapeutic and Diagnostic Strategies in Mesothelioma., PMID:40362535
A model workflow for microfluidic enrichment and genetic analysis of circulating melanoma cells., PMID:40316673
Treatment outcomes of BTK inhibitors and venetoclax with or without anti-CD20 monoclonal antibody in relapsed or refractory mantle cell lymphoma., PMID:40278919
Pancreatic Cancer: Pathogenesis and Clinical Studies., PMID:40182139
Rare Metastatic Mesothelioma Occupying Intra-Atrial Cavity, Released by an Emergency Surgery: A Case Report and Literature Review., PMID:40034201
Gastric-type endocervical adenocarcinoma, superficial myofibroblastoma, sex cord-stromal tumors, and HSIL in Peutz-Jeghers syndrome: a rare case report, genetic characterization, and review of literature., PMID:40018404
Spitz Spindle Cell/Reed Nevus With SQSTM1 :: NTRK2 Fusion and Atypical Features in an Older Male Patient: A Case Report and Review of Literature., PMID:39980385
Performance analysis of Leica Biosystems p16 monoclonal antibody in oropharyngeal squamous cell carcinoma., PMID:39856694
Toripalimab plus chemotherapy for metastatic muscle-invasive bladder cancer with a high tumor proportion score: a case report., PMID:39744627
Efficacy of immune checkpoint inhibitors in pulmonary sarcomatoid carcinoma and predictive potential of mutated TP53., PMID:39736248
Genomic Biomarkers Associated with Enfortumab Vedotin Outcomes for Patients with Advanced Urothelial Carcinoma: Analysis of UNITE Study Data., PMID:39709257
Gene Expression Profiling of the Peritumoral Immune Cell Infiltrate of Penile Squamous Cell Carcinomas., PMID:39596210
Comprehensive Genomic Assessment of Advanced-Stage GI Stromal Tumors Using the Japanese National Center for Cancer Genomics and Advanced Therapeutics Database., PMID:39447098
MTAP and p16 IHC as Markers for CDKN2A/B Loss in Meningiomas., PMID:39409918
The road to overcome pancreatic cancer: Where are we?, PMID:39403527
Re-irradiation of anaplastic meningioma: higher dose and concomitant Bevacizumab may improve progression-free survival., PMID:39358739
Comparative analysis of PD-L1 expression and molecular alterations in primary versus metastatic lung adenocarcinoma: a real-world study in China., PMID:39323996
Targeting TGF-β signaling, oxidative stress, and cellular senescence rescues osteoporosis in gerodermia osteodysplastica., PMID:39234801
Advances in the understanding of molecular genetics and therapy of Richter transformation in chronic lymphocytic leukemia., PMID:39219481
cIMPACT-NOW update 8: Clarifications on molecular risk parameters and recommendations for WHO grading of meningiomas., PMID:39212325
Rare mediastinal small round cell melanoma with synovial sarcoma-like immunophenotype: A potential diagnostic pitfall., PMID:39151249
Clinical, genomic and immune microenvironmental determinants of nivolumab response in head and neck squamous cell carcinoma., PMID:39136017
Primary extraskeletal osteosarcomas of the pleura: A clinicopathological, immunohistochemical, and molecular analysis of 4 cases., PMID:39117026
[Clinicopathological features of metastatic melanoma in effusion cytology of serosal cavity]., PMID:39103266
PRAME and Historical Immunohistochemical Antibodies Ki-67, P16, and HMB-45 in Ambiguous Melanocytic Tumors., PMID:38916203
Case report: Pilomatrix carcinoma with PDL1 expression and CDKN2A aberrant., PMID:38873609
Characteristics of T cell premature senescence in maintenance hemodialysis patients., PMID:38850344
Durable radiologic and molecular complete response following nivolumab in an HNSCC patient with UV signature and HIV., PMID:38781626
P16-CD8-Ki67 Triple Algorithm for Prediction of CDKN2A Mutations in Patients with Multiple Primary and Familial Melanoma., PMID:38667459
Therapeutic Advances and Challenges for the Management of HPV-Associated Oropharyngeal Cancer., PMID:38612819
Genomic determinants of response and resistance to inotuzumab ozogamicin in B-cell ALL., PMID:38551807
Mutational, immune microenvironment, and clinicopathological profiles of diffuse large B-cell lymphoma and follicular lymphoma with BCL6 rearrangement., PMID:38462571
Clinical and molecular characteristics of Jordanian oropharyngeal cancer patients according to P16 expression: a retrospective study and a report of a novel biomarker., PMID:38459388
Impact of PIK3CA and cell cycle pathway genetic alterations on durvalumab efficacy in patients with head and neck squamous cell carcinoma: Post hoc analysis of TRIUMPH study., PMID:38458039
Pan-cancer Genomic Analysis of AXL Mutations Reveals a Novel, Recurrent, Functionally Activating AXL W451C Alteration Specific to Myxofibrosarcoma., PMID:38369783
Comparison of Immunohistochemistry, Next-generation Sequencing and Fluorescence In Situ Hybridization for Detection of MTAP Loss in Pleural Mesothelioma., PMID:38185249
Classification of gliomas based on genome-wide DNA methylation profiles and immunohistochemical analysis: a short study., PMID:39963031
Genomic determinants of response and resistance to inotuzumab ozogamicin in B-cell ALL., PMID:38106221
Unveiling the role of MGMT and DAPK hypermethylation in response to anti-EGFR agents: Molecular insights for advancing HNSCC treatment., PMID:38095042
Genomic characterization of vulvar squamous cell carcinoma reveals differential gene expression based on clinical outcome., PMID:38086165
First-Line Ipatasertib, Atezolizumab, and Taxane Triplet for Metastatic Triple-Negative Breast Cancer: Clinical and Biomarker Results., PMID:38060199
miR-17-92 cluster-BTG2 axis regulates B-cell receptor signaling in mantle cell lymphoma., PMID:38050664
Loss of Histone H3K27 Trimethylation (H3K27me3) Expression as a Potential Diagnostic Pitfall in Sarcomatoid Carcinoma., PMID:37997394
Podocyte injury at young age causes premature senescence and worsens glomerular aging., PMID:37855038
A novel TPD52L2-ROS1 gene fusion expanding the molecular alterations in inflammatory myofibroblastic tumor: case report and literature review., PMID:37735390
Determinants of Survival with Combined HER2 and PD-1 Blockade in Metastatic Esophagogastric Cancer., PMID:37406106
Treatment of older patients with mantle cell lymphoma in the era of novel agents., PMID:37357622
Impact of Squamous Histology on Clinical Outcomes and Molecular Profiling in Metastatic Urothelial Carcinoma Patients Treated With Immune Checkpoint Inhibitors or Enfortumab Vedotin., PMID:37316414
For research use only. Not for human or drug use.
