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Anti-P2RY2 Antibody (R3K58)

Catalog #:   RHE31401 Specific References (32) DATASHEET
Host species: Mouse
Isotype: IgG2b
Applications: ELISA, FCM
Accession: P41231
Overview

Catalog No.

RHE31401

Species reactivity

Human

Host species

Mouse

Isotype

IgG2b

Clonality

Monoclonal

Tested applications

ELISA: 1:10000, FCM: 1:200-1:400

Target

P2Y2, Purinergic receptor, P2U purinoceptor 1, P2RU1, P2RY2, P2Y purinoceptor 2, ATP receptor, P2U1, P2U receptor 1

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P41231

Applications

ELISA, FCM

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R3K58

Data Image
  • Flow Cytometry
    Flow cytometric analysis of Hela cells using P2RY2 mouse mAb (green) and negative control (red).
References

Circulating Naturally Occurring Antibodies to P2RY2 Are Decreased in Alzheimer's Disease., PMID:35342089

Expression of astrocyte-related receptors in cortical dysplasia with intractable epilepsy., PMID:25003238

P2Y2 nucleotide receptors mediate metalloprotease-dependent phosphorylation of epidermal growth factor receptor and ErbB3 in human salivary gland cells., PMID:20064929

Concomitant activation of P2Y(2) and P2Y(6) receptors on monocytes is required for TLR1/2-induced neutrophil migration by regulating IL-8 secretion., PMID:19735076

Promoting MPhi transepithelial migration by stimulating the epithelial cell P2Y(2) receptor., PMID:19634190

Potential role of purinergic signaling in lithium-induced nephrogenic diabetes insipidus., PMID:19244398

Articular chondrocytes express connexin 43 hemichannels and P2 receptors - a putative mechanoreceptor complex involving the primary cilium?, PMID:19207989

Innervation and receptor profiles of the human apocrine (epitrichial) sweat gland: routes for intervention in bromhidrosis., PMID:18637900

Selective loss of P2Y2 nucleotide receptor immunoreactivity is associated with Alzheimer's disease neuropathology., PMID:18506388

ATP/UTP activate cation-permeable channels with TRPC3/7 properties in rat cardiomyocytes., PMID:18502908

Involvement of purinergic P2 receptors in experimental retinal neovascularization., PMID:18350440

Involvement of apical P2Y2 receptor-regulated CFTR activity in muscarinic stimulation of Cl(-) reabsorption in rat submandibular gland., PMID:18337312

Deficiency of purinergic P2Y receptors in aganglionic intestine in Hirschsprung's disease., PMID:17962960

The P2Y2 nucleotide receptor requires interaction with alpha v integrins to access and activate G12., PMID:17452627

Regulation of extracellular UTP-activated Cl- current by P2Y-PLC-PKC signaling and ATP hydrolysis in mouse ventricular myocytes., PMID:17291397

Dual roles of diadenosine polyphosphates in corneal epithelial cell migration., PMID:17003445

The P2Y2 nucleotide receptor interacts with alphav integrins to activate Go and induce cell migration., PMID:16186116

Changes in P2Y2 receptor localization on adrenaline- and noradrenaline-containing chromaffin cells in the rat adrenal gland during development and aging., PMID:16140489

P2Y nucleotide receptor interaction with alpha integrin mediates astrocyte migration., PMID:16135088

Identification of P2Y receptor subtypes in human muller glial cells by physiology, single cell RT-PCR, and immunohistochemistry., PMID:16043877

Purinergic receptors are part of a signaling system for keratinocyte proliferation, differentiation, and apoptosis in human fetal epidermis., PMID:14708618

Src homology 3 binding sites in the P2Y2 nucleotide receptor interact with Src and regulate activities of Src, proline-rich tyrosine kinase 2, and growth factor receptors., PMID:14670955

P2Y(2) receptor agonist INS37217 enhances functional recovery after detachment caused by subretinal injection in normal and rds mice., PMID:14507899

Thrombin-induced platelet PAR4 activation: role of glycoprotein Ib and ADP., PMID:12871418

P2X and P2Y purinoceptor expression in pancreas from streptozotocin-diabetic rats., PMID:12850289

Immunohistochemical expressions of mGluR5, P2Y2 receptor, PLC-beta1, and IP3R-I and -II in Merkel cells in rat sinus hair follicles., PMID:12802596

The P2Y2 nucleotide receptor mediates UTP-induced vascular cell adhesion molecule-1 expression in coronary artery endothelial cells., PMID:12714597

Purinergic receptor expression in the apical plasma membrane of rat uterine epithelial cells during implantation., PMID:12098222

Extracellular nucleotides inhibit growth of human oesophageal cancer cells via P2Y(2)-receptors., PMID:11870549

An RGD sequence in the P2Y(2) receptor interacts with alpha(V)beta(3) integrins and is required for G(o)-mediated signal transduction., PMID:11331301

Cellular localization of P2Y(2) purinoceptor in rat renal inner medulla and lung., PMID:10644654

Agonist-induced internalization of the P2Y2 receptor., PMID:9730907

Datasheet

Document Download

Anti-P2RY2 Antibody (R3K58).pdf

 

$ 220
Product specifications
50 μg 220 100 μg 350

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Anti-P2RY2 Antibody (R3K58) [RHE31401]
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