Please ensure Javascript is enabled for purposes of website accessibility
Home / Products / Antibody / Recombinant Antibody

Anti-WNT5A Antibody (R3K55)

Catalog #:   RHE30703 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG1
Applications: IHC
Accession: P41221
Overview

Catalog No.

RHE30703

Species reactivity

Human

Host species

Mouse

Isotype

IgG1

Clonality

Monoclonal

Tested applications

IHC: 1:200-1:1000

Target

Protein Wnt-5a, WNT5A

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P41221

Applications

IHC

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R3K55

Data Image
  • Immunohistochemical
    Immunohistochemical analysis of paraffin-embedded human lung cancer (A), thyroid cancer (B), lymph node (C) and brain (D) showing cytoplasmic and extracellular matrix localization using WNT5A mouse mAb with DAB staining.
References

The impact of autoimmune thyroid disease on cognitive and psychiatric disorders: focus on clinical, pre-clinical and molecular studies., PMID:40445744

Cancer-associated fibroblasts promote growth and dissemination of esophageal squamous cell carcinoma cells by secreting WNT family member 5A., PMID:39954174

Non-Canonical Wnt16 and microRNA-145 Mediate the Response of Human Bone Marrow Stromal Cells to Additively Manufactured Porous 3-Dimensional Biomimetic Titanium-Aluminum-Vanadium Constructs., PMID:39937002

Targeting ROR2 homooligomerization disrupts ROR2-dependent signaling and suppresses stem-like cell properties of human breast adenocarcinoma., PMID:39829682

Identification of a novel anti-ROR1 nanobody through phage display and its biochemical characterization., PMID:39645564

Neutrophil pyroptosis regulates corneal wound healing and post-injury neovascularisation., PMID:39496510

Structural insights into Frizzled3 through nanobody modulators., PMID:39174501

Requirement of a Wnt5A-microbiota axis in the maintenance of gut B-cell repertoire and protection from infection., PMID:39140737

9-O-monoethyl succinate berberine effectively blocks the PI3K/AKT signaling pathway by targeting Wnt5a protein in inhibiting osteosarcoma growth., PMID:39047413

Receptor tyrosine kinase-like orphan receptor serves as a potential target in cancer immunotherapy., PMID:38973261

How receptor tyrosine kinase-like orphan receptor 1 meets its partners in chronic lymphocytic leukemia., PMID:38949887

Structure and function of the ROR2 cysteine-rich domain in vertebrate noncanonical WNT5A signaling., PMID:38780011

Synovial osteoclastogenesis mediated by chondrocyte-secreted TNFα promotes TMJ condylar resorption., PMID:38720613

Wnt16 Increases Bone-to-Implant Contact in an Osteopenic Rat Model by Increasing Proliferation and Regulating the Differentiation of Bone Marrow Stromal Cells., PMID:38517621

The Notch1 signaling pathway directly modulates the human RANKL-induced osteoclastogenesis., PMID:38040752

Wnt1 induces osteoblastic changes in a well-established osteolytic skeletal metastatic model derived from breast cancer., PMID:37840014

Ehrlichia Wnt SLiM ligand mimic deactivates the Hippo pathway to engage the anti-apoptotic Yap-GLUT1-BCL-xL axis., PMID:37530530

Stricturing Crohn's Disease Single-Cell RNA Sequencing Reveals Fibroblast Heterogeneity and Intercellular Interactions., PMID:37507073

Ehrlichia Wnt short linear motif ligand mimetic deactivates the Hippo pathway to engage the anti-apoptotic Yap-GLUT1-BCL-xL axis., PMID:36945589

WNT5A-ROR2 axis mediates VEGF dependence of BRAF mutant melanoma., PMID:36539575

ATBF1 is a potential diagnostic marker of histological grade and functions via WNT5A in breast cancer., PMID:36476423

Periodontal ligaments enhance neurite outgrowth in trigeminal ganglion neurons through Wnt5a production induced by mechanical stimulation., PMID:36374171

WNT5A drives interleukin-6-dependent epithelial-mesenchymal transition via the JAK/STAT pathway in keloid pathogenesis., PMID:36225328

Pep27 Mutant Immunization Inhibits Caspase-14 Expression to Alleviate Inflammatory Bowel Disease via Treg Upregulation., PMID:36144473

Frequently used antiemetic agent dexamethasone enhances the metastatic behaviour of select breast cancer cells., PMID:36107918

Wnt5a/β-catenin axis is involved in the downregulation of AT2 lineage by PAI-1., PMID:36098461

Fatty Acid Signaling Impacts Prostate Cancer Lineage Plasticity in an Autocrine and Paracrine Manner., PMID:35884514

Berberine retarded the growth of gastric cancer xenograft tumors by targeting hepatocyte nuclear factor 4α., PMID:35582103

Aniridia-related keratopathy relevant cell signaling pathways in human fetal corneas., PMID:35551459

In utero exposure to maternal anti-aquaporin-4 antibodies alters brain vasculature and neural dynamics in male mouse offspring., PMID:35442708

Memory B-cell like chronic lymphocytic leukaemia is associated with specific methylation profile of WNT5A promoter and undetectable expression of WNT5A gene., PMID:35333703

WNT5A Interacts With FZD5 and LRP5 to Regulate Proliferation and Self-Renewal of Endometrial Mesenchymal Stem-Like Cells., PMID:35295855

Aberrantly expressed Wnt5a in nurse-like cells drives resistance to Venetoclax in chronic lymphocytic leukemia., PMID:35210425

TNF-α Activating Osteoclasts in Patients with Psoriatic Arthritis Enhances the Recruitment of Osteoclast Precursors: A Plausible Role of WNT5A-MCP-1 in Osteoclast Engagement in Psoriatic Arthritis., PMID:35055107

Changes in Expression of Specific mRNA Transcripts after Single- or Re-Irradiation in Mouse Testes., PMID:35052491

IgD promotes pannus formation by activating Wnt5A-Fzd5-CTHRC1-NF-κB signaling pathway in FLS of CIA rats and the regulation of IgD-Fc-Ig fusion protein., PMID:34688134

WNT/β-Catenin Signaling Promotes TGF-β-Mediated Activation of Human Cardiac Fibroblasts by Enhancing IL-11 Production., PMID:34576234

Targeting the Receptor Tyrosine Kinase ROR1 by Small Molecules., PMID:34490515

FOSL2 promotes VEGF-independent angiogenesis by transcriptionnally activating Wnt5a in breast cancer-associated fibroblasts., PMID:33754039

IGLV3-21R110 identifies an aggressive biological subtype of chronic lymphocytic leukemia with intermediate epigenetics., PMID:33211804

Non-Canonical WNT5A Signaling Through RYK Contributes to Aggressive Phenotype of the Rheumatoid Fibroblast-Like Synoviocytes., PMID:33178184

Egr-1 mediates low-dose arecoline induced human oral mucosa fibroblast proliferation via transactivation of Wnt5a expression., PMID:33167868

Wnt5a expression and prognosis in stage II-III colon cancer., PMID:33045677

Beta-catenin non-canonical pathway: A potential target for inflammatory and hyperproliferative state via expression of transglutaminase 2 in psoriatic skin keratinocyte., PMID:32816372

WNT5A augments cell invasiveness by inducing CXCL8 in HER2-positive breast cancer cells., PMID:32736336

Clinical Management and Therapeutic Strategies for the Thyroid-Associated Ophthalmopathy: Current and Future Perspectives., PMID:32567373

Non-canonical WNT5a regulates Epithelial-to-Mesenchymal Transition in the mouse ovarian surface epithelium., PMID:32546756

Fam70A binds Wnt5a to regulate meiosis and quality of mouse oocytes., PMID:32391621

Smooth-muscle-derived WNT5A augments allergen-induced airway remodelling and Th2 type inflammation., PMID:32317758

Wnt5a-induced M2 polarization of tumor-associated macrophages via IL-10 promotes colorectal cancer progression., PMID:32228612

Datasheet

Document Download

Anti-WNT5A Antibody (R3K55).pdf

 

$ 220
Product specifications
50 μg 220 100 μg 350

Contact Information

Order: order@antibodysystem.com

Mail: support@antibodysystem.com

Distributor list

For research use only. Not for human or drug use.

Need help with your order?

Find out more about placing an order here

Anti-WNT5A Antibody (R3K55) [RHE30703]
Terms of sale Website terms of use Cookie policy Privacy
Copyright © 2025 AntibodySystem SAS. All Rights Reserved.            All Products are for Research Use Only