Catalog No.
RHE15301
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
ELISA: 1:10000, FCM: 1:200-1:400, IHC: 1:200-1:1000, WB: 1:500-1:2000
Target
Transcription factor SOX-11, SOX11
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P35716
Applications
ELISA, FCM, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3J94
Optical genome mapping reveals diverse mechanisms of cyclin activation in mantle cell lymphomas lacking IGH::CCND1., PMID:40381701
The diagnostic utility of SOX11 Immunohistochemical expression in malignant peripheral nerve sheath tumors and their potential mimickers., PMID:39892100
Molecular characterization of a rare case of high-grade B-cell lymphoma with MYC, BCL2, BCL6, and CCND1 rearrangements., PMID:38914869
[Clinicopathological features and prognosis analysis of bone marrow biopsy involvement in 95 cases with mantle cell lymphoma]., PMID:38825910
Primitive Embryonic-Type Neuroectodermal/Glandular Complexes in Testicular Germ Cell Tumors: A Mimic of Embryonic-Type Neuroectodermal Tumor., PMID:38712621
miR-17-92 cluster-BTG2 axis regulates B-cell receptor signaling in mantle cell lymphoma., PMID:38050664
A Push to Consider Mantle Cell Lymphoma in Adults with Leukemia/Lymphoma with Blastoid Morphology., PMID:37873796
Tumor Microenvironment and Immunotherapy-Based Approaches in Mantle Cell Lymphoma., PMID:35804999
Expression and Clinicopathological Significance of SOX11 in Small-Cell Lung Cancer., PMID:35402616
Mantle cell lymphoma in 2022-A comprehensive update on molecular pathogenesis, risk stratification, clinical approach, and current and novel treatments., PMID:35266562
Modeling HNF1B-associated monogenic diabetes using human iPSCs reveals an early stage impairment of the pancreatic developmental program., PMID:34450036
Mitotic WNT signalling orchestrates neurogenesis in the developing neocortex., PMID:34431536
Leukemic Variant of Mantle Cell Lymphoma: Clinical Presentation and Management., PMID:34269910
Mantle cell lymphoma - advances in molecular biology, prognostication and treatment approaches., PMID:33783838
Single nucleotide variants in immune-response genes and the tumor microenvironment composition predict progression of mantle cell lymphoma., PMID:33648463
[Sequential development of mantle cell lymphoma following chronic lymphocytic leukemia]., PMID:32224586
Periodontal ligament cells regulate osteogenesis via miR-299-5p in mesenchymal stem cells., PMID:31951879
Diagnostic accuracy of SOX11 immunohistochemistry in mantle cell lymphoma: A meta-analysis., PMID:31714947
Primary Low-Grade B-Cell Lymphoma of Skull With Translocation Between Immunoglobulin and Interferon Regulatory Factor 4 Genes., PMID:31631721
CCND2 and CCND3 hijack immunoglobulin light-chain enhancers in cyclin D1- mantle cell lymphoma., PMID:30538135
Phosphorylation of the neurogenic transcription factor SOX11 on serine 133 modulates neuronal morphogenesis., PMID:30385877
SOX11 augments BCR signaling to drive MCL-like tumor development., PMID:29615403
SOX11 expression as a MRD molecular marker for MCL in comparison with t(11;14) and IGH rearrangement., PMID:29520657
Composite mantle cell lymphoma and chronic lymphocytic leukemia/small lymphocytic lymphoma., PMID:28109040
Heterogeneous pattern of DNA methylation in developmentally important genes correlates with its chromatin conformation., PMID:28081716
Reproducibility of SOX-11 detection in decalcified bone marrow tissue in mantle cell lymphoma patients., PMID:27720733
Expression of SOX11, PAX5, TTF-1 and ISL-1 in medulloblastoma., PMID:27623204
A cyclin D1-negative mantle cell lymphoma with an IGL-CCND2 translocation that relapsed with blastoid morphology and aggressive clinical behavior., PMID:27457074
Diagnostic utility of SOX11 immunohistochemistry in differentiating cutaneous spread of mantle cell lymphoma from primary cutaneous B-cell lymphomas., PMID:26762898
[Expression of CD68, cyclin D1 and rearrangement of bcl-6 gene are adverse prognostic factors in diffuse large B-cell lymphoma]., PMID:26705179
Repeat course of rabbit antithymocyte globulin as salvage following initial therapy with rabbit antithymocyte globulin in acquired aplastic anemia., PMID:25862703
SOX11, CCND1, BCL1/IgH and IgH-VDJ: a battle of minimal residual disease markers in mantle cell lymphoma?, PMID:25629991
SOX11 expression in chronic lymphocytic leukemia correlates with adverse prognostic markers., PMID:25608839
Immunoglobulin expressions are only associated with MCPyV-positive Merkel cell carcinomas but not with MCPyV-negative ones: comparison of prognosis., PMID:25392922
Utility and diagnostic pitfalls of SOX11 monoclonal antibodies in mantle cell lymphoma and other lymphoproliferative disorders., PMID:25229384
Small cell lung cancer cells express the late stage gBK tumor antigen: a possible immunotarget for the terminal disease., PMID:24936214
Polyclonal antibody targeting SOX11 cannot differentiate mantle cell lymphoma from B-cell non-Hodgkin lymphomas., PMID:24225745
Newly available antibodies with practical applications in surgical pathology., PMID:24225578
Assessment of SOX11 expression in routine lymphoma tissue sections: characterization of new monoclonal antibodies for diagnosis of mantle cell lymphoma., PMID:24145648
The role of SOX11 in mantle cell lymphoma., PMID:24001358
Increased expression of sex determining region Y-box 11 (SOX11) in cutaneous malignant melanoma., PMID:23867449
The chromatin remodeler CHD7 regulates adult neurogenesis via activation of SoxC transcription factors., PMID:23827709
Cytarabine, Ki-67, and SOX11 in patients with mantle cell lymphoma receiving rituximab-containing autologous stem cell transplantation during first remission., PMID:23775587
microRNA expression profiles identify subtypes of mantle cell lymphoma with different clinicobiological characteristics., PMID:23640973
Embryonic mammary signature subsets are activated in Brca1-/- and basal-like breast cancers., PMID:23506684
Molecular subsets of mantle cell lymphoma defined by the IGHV mutational status and SOX11 expression have distinct biologic and clinical features., PMID:22915760
Expanded clinical and experimental use of SOX11 - using a monoclonal antibody., PMID:22738398
Mantle cell lymphoma: 2012 update on diagnosis, risk-stratification, and clinical management., PMID:22615102
WT1 and Sox11 regulate synergistically the promoter of the Wnt4 gene that encodes a critical signal for nephrogenesis., PMID:22465478
Indolent mantle cell leukemia: a clinicopathological variant characterized by isolated lymphocytosis, interstitial bone marrow involvement, kappa light chain restriction, and good prognosis., PMID:21508124