Anti-SOX11 Antibody (R3J93)

Catalog No.

RHE15302

Species reactivity

Human

Host species

Mouse

Isotype

IgG2b

Clonality

Monoclonal

Tested applications

ELISA: 1:10000, FCM: 1:200-1:400

Target

Transcription factor SOX-11, SOX11

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P35716

Applications

ELISA, FCM

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R3J93

Optical genome mapping reveals diverse mechanisms of cyclin activation in mantle cell lymphomas lacking IGH::CCND1., PMID:40381701

The diagnostic utility of SOX11 Immunohistochemical expression in malignant peripheral nerve sheath tumors and their potential mimickers., PMID:39892100

Molecular characterization of a rare case of high-grade B-cell lymphoma with MYC, BCL2, BCL6, and CCND1 rearrangements., PMID:38914869

[Clinicopathological features and prognosis analysis of bone marrow biopsy involvement in 95 cases with mantle cell lymphoma]., PMID:38825910

Primitive Embryonic-Type Neuroectodermal/Glandular Complexes in Testicular Germ Cell Tumors: A Mimic of Embryonic-Type Neuroectodermal Tumor., PMID:38712621

miR-17-92 cluster-BTG2 axis regulates B-cell receptor signaling in mantle cell lymphoma., PMID:38050664

A Push to Consider Mantle Cell Lymphoma in Adults with Leukemia/Lymphoma with Blastoid Morphology., PMID:37873796

Tumor Microenvironment and Immunotherapy-Based Approaches in Mantle Cell Lymphoma., PMID:35804999

Expression and Clinicopathological Significance of SOX11 in Small-Cell Lung Cancer., PMID:35402616

Mantle cell lymphoma in 2022-A comprehensive update on molecular pathogenesis, risk stratification, clinical approach, and current and novel treatments., PMID:35266562

Modeling HNF1B-associated monogenic diabetes using human iPSCs reveals an early stage impairment of the pancreatic developmental program., PMID:34450036

Mitotic WNT signalling orchestrates neurogenesis in the developing neocortex., PMID:34431536

Leukemic Variant of Mantle Cell Lymphoma: Clinical Presentation and Management., PMID:34269910

Mantle cell lymphoma - advances in molecular biology, prognostication and treatment approaches., PMID:33783838

Single nucleotide variants in immune-response genes and the tumor microenvironment composition predict progression of mantle cell lymphoma., PMID:33648463

[Sequential development of mantle cell lymphoma following chronic lymphocytic leukemia]., PMID:32224586

Periodontal ligament cells regulate osteogenesis via miR-299-5p in mesenchymal stem cells., PMID:31951879

Diagnostic accuracy of SOX11 immunohistochemistry in mantle cell lymphoma: A meta-analysis., PMID:31714947

Primary Low-Grade B-Cell Lymphoma of Skull With Translocation Between Immunoglobulin and Interferon Regulatory Factor 4 Genes., PMID:31631721

CCND2 and CCND3 hijack immunoglobulin light-chain enhancers in cyclin D1- mantle cell lymphoma., PMID:30538135

Phosphorylation of the neurogenic transcription factor SOX11 on serine 133 modulates neuronal morphogenesis., PMID:30385877

SOX11 augments BCR signaling to drive MCL-like tumor development., PMID:29615403

SOX11 expression as a MRD molecular marker for MCL in comparison with t(11;14) and IGH rearrangement., PMID:29520657

Composite mantle cell lymphoma and chronic lymphocytic leukemia/small lymphocytic lymphoma., PMID:28109040

Heterogeneous pattern of DNA methylation in developmentally important genes correlates with its chromatin conformation., PMID:28081716

Reproducibility of SOX-11 detection in decalcified bone marrow tissue in mantle cell lymphoma patients., PMID:27720733

Expression of SOX11, PAX5, TTF-1 and ISL-1 in medulloblastoma., PMID:27623204

A cyclin D1-negative mantle cell lymphoma with an IGL-CCND2 translocation that relapsed with blastoid morphology and aggressive clinical behavior., PMID:27457074

Diagnostic utility of SOX11 immunohistochemistry in differentiating cutaneous spread of mantle cell lymphoma from primary cutaneous B-cell lymphomas., PMID:26762898

[Expression of CD68, cyclin D1 and rearrangement of bcl-6 gene are adverse prognostic factors in diffuse large B-cell lymphoma]., PMID:26705179

Repeat course of rabbit antithymocyte globulin as salvage following initial therapy with rabbit antithymocyte globulin in acquired aplastic anemia., PMID:25862703

SOX11, CCND1, BCL1/IgH and IgH-VDJ: a battle of minimal residual disease markers in mantle cell lymphoma?, PMID:25629991

SOX11 expression in chronic lymphocytic leukemia correlates with adverse prognostic markers., PMID:25608839

Immunoglobulin expressions are only associated with MCPyV-positive Merkel cell carcinomas but not with MCPyV-negative ones: comparison of prognosis., PMID:25392922

Utility and diagnostic pitfalls of SOX11 monoclonal antibodies in mantle cell lymphoma and other lymphoproliferative disorders., PMID:25229384

Small cell lung cancer cells express the late stage gBK tumor antigen: a possible immunotarget for the terminal disease., PMID:24936214

Polyclonal antibody targeting SOX11 cannot differentiate mantle cell lymphoma from B-cell non-Hodgkin lymphomas., PMID:24225745

Newly available antibodies with practical applications in surgical pathology., PMID:24225578

Assessment of SOX11 expression in routine lymphoma tissue sections: characterization of new monoclonal antibodies for diagnosis of mantle cell lymphoma., PMID:24145648

The role of SOX11 in mantle cell lymphoma., PMID:24001358

Increased expression of sex determining region Y-box 11 (SOX11) in cutaneous malignant melanoma., PMID:23867449

The chromatin remodeler CHD7 regulates adult neurogenesis via activation of SoxC transcription factors., PMID:23827709

Cytarabine, Ki-67, and SOX11 in patients with mantle cell lymphoma receiving rituximab-containing autologous stem cell transplantation during first remission., PMID:23775587

microRNA expression profiles identify subtypes of mantle cell lymphoma with different clinicobiological characteristics., PMID:23640973

Embryonic mammary signature subsets are activated in Brca1-/- and basal-like breast cancers., PMID:23506684

Molecular subsets of mantle cell lymphoma defined by the IGHV mutational status and SOX11 expression have distinct biologic and clinical features., PMID:22915760

Expanded clinical and experimental use of SOX11 - using a monoclonal antibody., PMID:22738398

Mantle cell lymphoma: 2012 update on diagnosis, risk-stratification, and clinical management., PMID:22615102

WT1 and Sox11 regulate synergistically the promoter of the Wnt4 gene that encodes a critical signal for nephrogenesis., PMID:22465478

Indolent mantle cell leukemia: a clinicopathological variant characterized by isolated lymphocytosis, interstitial bone marrow involvement, kappa light chain restriction, and good prognosis., PMID:21508124

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