Catalog No.
RHE10103
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
ELISA: 1:10000, FCM: 1:200-1:400, IF: 1:200-1:1000
Target
PGH synthase 2, Prostaglandin G/H synthase 2, Cyclooxygenase-2, PTGS2, COX2, PGHS-2, PHS II, Prostaglandin-endoperoxide synthase 2, COX-2, Prostaglandin H2 synthase 2
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P35354
Applications
ELISA, FCM, IF
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3J75
Immunohistochemical evaluation of cyclooxygenase-2 expression in feline nasal malignant epithelial tumours., PMID:40519042
Peripheral Immune-Inflammatory Pathways in Major Depressive Disorder, Bipolar Disorder, and Schizophrenia: Exploring Their Potential as Treatment Targets., PMID:40514640
Cyclooxygenase-2 Overexpression and its Association with Histopathological Features of Human Malignant Melanoma., PMID:40487258
Therapeutic potential of Coprinus comatus nanogels: Antiarthritic and anti-inflammatory effects in rheumatoid arthritis models., PMID:40342737
Puriton attenuates the asthma severity in ovalbumin-induced murine model via balancing Th1/Th2 and inhibiting inflammation., PMID:40323927
Secretory IgA binding to FCRL3 triggers shared inflammatory cytokine secretion by human regulatory T cells and effector T cells., PMID:40313182
Expression of cyclooxygenase-2 (COX-2) in epithelial ovarian cancers in an Indigenous African population of Kano, Nigeria., PMID:40248271
Expression of cyclooxygenase-2 (COX-2) in colorectal carcinoma in an indigenous African population of Kano, Nigeria., PMID:40171463
IgA2 ACPA Drives a Hyper-Inflammatory Phenotype in Macrophages via ATP Synthase and COX2., PMID:40170376
IL-33 facilitates endoplasmic reticulum stress and pyroptosis in LPS-stimulated ARDS model in vitro., PMID:40118005
Ameliorative Effects of Escin on Inflammation via Glucocorticoid Receptor (GR) in Atopic Dermatitis (AD) Mouse Model., PMID:40081901
Effect of the glucagon-like peptide-1 receptor agonists dulaglutide on kidney outcomes in db/db mice., PMID:39805329
Celecoxib Combined with Tocilizumab Has Anti-Inflammatory Effects and Promotes the Recovery of Damaged Cartilage via the Nrf2/HO-1 Pathway In Vitro., PMID:39766343
Effects of Crescentia cujete (L.) fruit extract on the profile of hematology of ranchu goldfish (Carassius auratus)., PMID:39737036
Impact of Lysine to Methionine Ratios on Antioxidant Capacity and Immune Function in the Rumen of Tibetan Sheep: An RNA-Seq Analysis., PMID:39708312
Activation of mixed lineage kinase 3 by fine particulate matter induces skin inflammation in human keratinocytes., PMID:39547318
Screening of anti-inflammatory active components in Sabia schumanniana Diels by affinity ultrafiltration and UHPLC-Q-Exactive Orbitrap mass spectrometry., PMID:39306211
In vitro analysis of VEGF-mediated endothelial permeability and the potential therapeutic role of Anti-VEGF in severe dengue., PMID:39263317
Guaijaverin And Epigallocatechin Gallate Exerts Antiinflammatory And Antiallergenic Effects Through Interleukin-12 Production., PMID:39229731
Immune-mediated impairment of tonic immobility defensive behavior in an experimental model of colonic inflammation., PMID:39218820
Lumbrokinase Extracted from Earthworms Synergizes with Bevacizumab and Chemotherapeutics in Treating Non-Small Cell Lung Cancer by Targeted Inactivation of BPTF/VEGF and NF-κB/COX-2 Signaling., PMID:39062456
Combining Anti-Mitochondrial Antibodies, Anti-Histone, and PLA2/COX Biomarkers to Increase Their Diagnostic Accuracy for Autism Spectrum Disorders., PMID:38928576
PGE2 induced miR365/IL-6/STAT3 signaling mediates dendritic cell dysfunction in cancer., PMID:38797363
ANO6 (TMEM16F) inhibits gastrointestinal stromal tumor growth and induces ferroptosis., PMID:38756246
PM2.5 exposure upregulates pro-inflammatory protein expression in human microglial cells via oxidant stress and TLR4/NF-κB pathway., PMID:38657455
Xin-Yi-Qing-Fei-Tang and its critical components reduce asthma symptoms by suppressing GM-CSF and COX-2 expression in RBL-2H3 cells., PMID:38631485
Smoking enhances proliferation, inflammatory markers, and immunoglobulins in peripheral blood mononuclear cells from Graves' patients., PMID:38614122
The inositol-requiring enzyme 1 (IRE1) endoplasmic reticulum stress pathway promotes MDA-MB-231 cell survival and renewal in response to the aryl-ureido fatty acid CTU., PMID:38608921
Induction of human-fetal-membrane remodeling in-vitro by the alpha hemolysin of Escherichia coli., PMID:38401207
Antagonism of regulatory ISGs enhances the anti-melanoma efficacy of STING agonists., PMID:38312842
Inflammation-Driven Nanohitchhiker Enhances Postoperative Immunotherapy by Alleviating Prostaglandin E2-Mediated Immunosuppression., PMID:38300288
Endocannabinoid regulation in the cervix during pregnancy: insights into molecular mechanisms of premature labor., PMID:38271800
Treponema pallidum protein Tp47 induced prostaglandin E2 to inhibit the phagocytosis in human macrophages., PMID:38258964
M1 macrophage-derived oncostatin M induces osteogenic differentiation of ligamentum flavum cells through the JAK2/STAT3 pathway., PMID:38222812
Codelivery of TGFβ and Cox2 siRNA inhibits HCC by promoting T-cell penetration into the tumor and improves response to Immune Checkpoint Inhibitors., PMID:38204925
Microbiota promotes recruitment and pro-inflammatory response of caecal macrophages during E. tenella infection., PMID:38098020
Blockade of EP4 by ASP7657 Modulates Myeloid Cell Differentiation In Vivo and Enhances the Antitumor Effect of Radiotherapy., PMID:38058393
Anti-CMV therapy, what next? A systematic review., PMID:38053548
Extra-adrenal aldosterone: a mini review focusing on the physiology and pathophysiology of intrarenal aldosterone., PMID:37847370
Molecular Insights into the Macrophage Immunomodulatory Effects of Scrophulariae Radix Polysaccharides., PMID:37830509
LPS/TLR4 Pathway Regulates IgA1 Secretion to Induce IgA Nephropathy., PMID:37820669
Celecoxib-Loaded Cubosomal Nanoparticles as a Therapeutic Approach for Staphylococcus aureus In Vivo Infection., PMID:37764091
The Functional Role of Myogenin in Cardiomyoblast H9c2 Cells Treated with High Glucose and Palmitic Acid: Insights into No-Rejection Heart Transplantation., PMID:37685838
New investigation of anti-inflammatory activity of Polycladia crinita and biosynthesized selenium nanoparticles: isolation and characterization., PMID:37670273
Analysis of a new therapeutic target and construction of a prognostic model for breast cancer based on ferroptosis genes., PMID:37643511
ER and COX2 expression in endometrial hyperplasia processes., PMID:37603513
β2-adrenergic receptor expression in patients receiving bevacizumab therapy for metastatic melanoma., PMID:37551424
BTK inhibition potentiates anti-PD-L1 treatment in murine melanoma: potential role for MDSC modulation in immunotherapy., PMID:37528320
Cineole inhibits the biosynthesis of leukotrienes and prostaglandins to alleviate allergic rhinitis: Insights from metabolomics., PMID:37481900
Involvement of the visfatin/toll-like receptor 4 signaling axis in human dental pulp cell senescence: Protection via toll-like receptor 4 blockade., PMID:37404665
For research use only. Not for human or drug use.
