Catalog No.
RHD99701
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
ELISA: 1:10000, FCM: 1:200-1:400, IF: 1:200-1:1000
Target
NACHRA3, Neuronal acetylcholine receptor subunit alpha-3, CHRNA3
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P32297
Applications
ELISA, FCM, IF
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3J37
Nicotinic Acetylcholine Receptor Expression in Merkel Cell Carcinoma Is Associated With Clinical and Histopathologic Parameters., PMID:39814046
Abundant extrasynaptic expression of α3β4-containing nicotinic acetylcholine receptors in the medial habenula-interpeduncular nucleus pathway in mice., PMID:38902419
Sensory innervation of masseter, temporal and lateral pterygoid muscles in common marmosets., PMID:38155190
Disconnected Cardiac Autonomic Nerves in Genetic Ganglionic Acetylcholine Receptor Alpha-3 Subunit Deficiency., PMID:37161764
Sensory innervation of masseter, temporal and lateral pterygoid muscles in common marmosets., PMID:36798270
Antibodies to the α3 subunit of the ganglionic-type nicotinic acetylcholine receptors in patients with autoimmune encephalitis., PMID:32980672
Case of autoimmune autonomic ganglionopathy manifesting anhidrosis., PMID:28620980
Adult-onset Opsoclonus-Myoclonus Syndrome Associated With Ganglionic Acetylcholine Receptor Autoantibody., PMID:27801769
Regulation of Tlx3 by Pax6 is required for the restricted expression of Chrnα3 in Cerebellar Granule Neuron progenitors during development., PMID:27452274
Association between Anti-Ganglionic Nicotinic Acetylcholine Receptor (gAChR) Antibodies and HLA-DRB1 Alleles in the Japanese Population., PMID:26807576
Cholinergic epithelial cell with chemosensory traits in murine thymic medulla., PMID:25300645
CHRNA3 polymorphism modifies lung adenocarcinoma risk in the Chinese Han population., PMID:24686516
Autoantibody-induced internalization of nicotinic acetylcholine receptor α3 subunit exogenously expressed in human embryonic kidney cells., PMID:23313381
Treatment-responsive pandysautonomia in an adolescent with ganglionic α3-AChR antibodies., PMID:22130491
Efficacy of immunotherapy in seropositive and seronegative putative autoimmune autonomic ganglionopathy., PMID:19506222
Ganglionic acetylcholine receptor autoantibody: oncological, neurological, and serological accompaniments., PMID:19506133
Special section on autoimmune autonomic ganglionopathy. Editorial., PMID:19217830
A Japanese case of autoimmune autonomic ganglionopathy (AAG) and a review of AAG cases in Japan., PMID:19195935
Clinical laboratory evaluation of autoimmune autonomic ganglionopathy: Preliminary observations., PMID:19155193
Antibody titers predict clinical features of autoimmune autonomic ganglionopathy., PMID:19144572
Autoimmune autonomic ganglionopathy with Sjögren's syndrome: significance of ganglionic acetylcholine receptor antibody and therapeutic approach., PMID:19097826
Other autonomic neuropathies associated with ganglionic antibody., PMID:19058765
Immunotherapy for autoimmune autonomic ganglionopathy., PMID:19056323
Autoimmune autonomic ganglionopathy with late-onset encephalopathy., PMID:19028442
Autonomic ganglia, acetylcholine receptor antibodies, and autoimmune ganglionopathy., PMID:18951069
Functional interactions between the SK2 channel and the nicotinic acetylcholine receptor in enteric neurons of the guinea pig ileum., PMID:17953675
Nicotinic acetylcholine receptors containing subunits alpha3 and alpha5 in rat nociceptive dorsal root ganglion neurons., PMID:17192625
The high-affinity choline transporter: a critical protein for sustaining cholinergic signaling as revealed in studies of genetically altered mice., PMID:16722248
Nicotinic acetylcholine receptor subunits and associated proteins in human sperm., PMID:15894803
Passive transfer of autoimmune autonomic neuropathy to mice., PMID:15306637
Production of antibodies to alpha(181-192) peptides of neuronal nicotinic acetylcholine receptor coupled to protein carriers in different orientations., PMID:14964862
Distribution of neuronal nicotinic acetylcholine receptors containing different alpha-subunits in the submucosal plexus of the guinea-pig., PMID:14766321
Increased exchange rate of histone H1 on chromatin by exogenous myogenin expression., PMID:12528897
Dystrophin stabilizes alpha 3- but not alpha 7-containing nicotinic acetylcholine receptor subtypes at the postsynaptic apparatus in the mouse superior cervical ganglion., PMID:12079404
Expression of nicotinic receptors in the skin of patients with palmoplantar pustulosis., PMID:11952537
Changes in nicotinic acetylcholine receptor subunits expression in brain of patients with Down syndrome and Alzheimer's disease., PMID:11771745
Structure of epitopes recognized by the antibodies to alpha(181-192) peptides of neuronal nicotinic acetylcholine receptors: extrapolation to the structure of acetylcholine-binding domain., PMID:11730940
Nicotinic acetylcholine receptor subtypes in rat superior cervical ganglion neurons as studied by sequential application of two alpha-subunit-specific antibodies., PMID:11297818
Neuronal nicotinic acetylcholine receptor alpha3 subunit protein in rat brain and sympathetic ganglion measured using a subunit-specific antibody: regional and ontogenic expression., PMID:11279289
Anti-neuronal nicotinic receptor antibodies in MG patients with thymoma., PMID:11137585
Neuronal nicotinic acetylcholine receptors of Drosophila melanogaster: the alpha-subunit dalpha3 and the beta-type subunit ARD co-assemble within the same receptor complex., PMID:11024458
Alpha subunit composition of nicotinic acetylcholine receptors in the rat autonomic ganglia neurons as determined with subunit-specific anti-alpha(181-192) peptide antibodies., PMID:10501468
Alpha4 but not alpha3 and alpha7 nicotinic acetylcholine receptor subunits are lost from the temporal cortex in Alzheimer's disease., PMID:10501210
Fast excitatory nicotinic transmission in the chick lateral spiriform nucleus., PMID:10479683
For research use only. Not for human or drug use.
