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Anti-MARCKS Antibody (R3H87)

Catalog #:   RHD85501 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG1
Applications: IHC
Accession: P29966
Overview

Catalog No.

RHD85501

Species reactivity

Human

Host species

Mouse

Isotype

IgG1

Clonality

Monoclonal

Tested applications

IHC: 1:100-1:200

Target

Myristoylated alanine-rich C-kinase substrate, 80K-L protein, PKCSL, Protein kinase C substrate, 80 kDa protein, light chain, PRKCSL, MACS, MARCKS

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P29966

Applications

IHC

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R3H87

Data Image
  • Immunohistochemical
    IHC-P analysis of colon tissue by MARCKS antibody (RHD85501). IHC-P was performed using sections of the formalin-fixed paraffin-embedded colon tissue;Result: Cells in lamina propria and glandular cells are positively stained at the cytoplasm and cell membrane.
References

Activation of Marck-like Genes and Proteins During Initial Phases of Regeneration in the Amputated Tail and Limb of the Lizard Podarcis muralis., PMID:40265370

Small Organic Compounds Mimicking the Effector Domain of Myristoylated Alanine-Rich C-Kinase Substrate Stimulate Female-Specific Neurite Outgrowth., PMID:37762575

MARCKS Effector Domain, a reversible lipid ligand, illuminates late stages of membrane fusion., PMID:37672336

Targeting carcinoma-associated mesothelial cells with antibody-drug conjugates in ovarian carcinomatosis., PMID:37555348

Analysis of phagocytosis by mIgM+ lymphocytes depending on monoclonal antibodies against IgM of largemouth bass (Micropterus salmoides)., PMID:35314332

The NEDD8-activating enzyme inhibitor MLN4924 reduces ischemic brain injury in mice., PMID:35101976

D-cysteine is an endogenous regulator of neural progenitor cell dynamics in the mammalian brain., PMID:34556581

A plasma-derived extracellular vesicle mRNA classifier for the detection of breast cancer., PMID:34268084

Intracellular amyloid hypothesis for ultra-early phase pathology of Alzheimer's disease., PMID:33876503

Single-cell RNA sequencing reveals that lung mesenchymal progenitor cells in IPF exhibit pathological features early in their differentiation trajectory., PMID:32636398

Interaction between Polysialic Acid and the MARCKS-ED Peptide at the Molecular Level., PMID:32412743

Novel Treatment Targets Based on Insights in the Etiology of Depression: Role of IL-6 Trans-Signaling and Stress-Induced Elevation of Glutamate and ATP., PMID:31362361

MARCKS regulates tonic and chronic active B cell receptor signaling., PMID:30209404

Mechanism of inhibition of taurolithocholate-induced retrieval of plasma membrane MRP2 by cyclic AMP and tauroursodeoxycholate., PMID:29192063

Generation and intracellular trafficking of a polysialic acid-carrying fragment of the neural cell adhesion molecule NCAM to the cell nucleus., PMID:28819302

Targeting mast cells: Uncovering prolific therapeutic role in myriad diseases., PMID:27694038

HMGB1, a pathogenic molecule that induces neurite degeneration via TLR4-MARCKS, is a potential therapeutic target for Alzheimer's disease., PMID:27557632

Vinorelbine and epirubicin share common features with polysialic acid and modulate neuronal and glial functions., PMID:26443186

Activation of lymphotoxin-beta receptor enhances the LPS-induced expression of IL-8 through NF-κB and IRF-1., PMID:25887375

Blood transcriptomic biomarkers in adult primary care patients with major depressive disorder undergoing cognitive behavioral therapy., PMID:25226551

Myristoylated Alanine Rich C Kinase Substrate (MARCKS) is essential to β2-integrin dependent responses of equine neutrophils., PMID:24857637

Structural characterization of a neuroblast-specific phosphorylated region of MARCKS., PMID:24590112

Endothelial cell adhesion to soluble vascular endothelial growth factor receptor-1 triggers a cell dynamic and angiogenic phenotype., PMID:24174428

MARCKS protein is phosphorylated and regulates calcium mobilization during human acrosomal exocytosis., PMID:23704996

MARCKS protein mediates hydrogen peroxide regulation of endothelial permeability., PMID:22927426

Directed migration of mouse macrophages in vitro involves myristoylated alanine-rich C-kinase substrate (MARCKS) protein., PMID:22623357

MARCKS actin-binding capacity mediates actin filament assembly during mitosis in human hepatic stellate cells., PMID:22555845

Serum antibodies against frameshift peptides in microsatellite unstable colorectal cancer patients with Lynch syndrome., PMID:19957108

Electroconvulsive seizure increases phosphorylation of PKC substrates, including GAP-43, MARCKS, and neurogranin, in rat brain., PMID:19837121

Mutation of the protein kinase C site in borna disease virus phosphoprotein abrogates viral interference with neuronal signaling and restores normal synaptic activity., PMID:19424436

Functional involvement of protein kinase C-betaII and its substrate, myristoylated alanine-rich C-kinase substrate (MARCKS), in insulin-stimulated glucose transport in L6 rat skeletal muscle cells., PMID:19252893

Prediction of the immunogenic potential of frameshift-mutated antigens in microsatellite instable cancer., PMID:18506693

Investigation into the mechanism regulating MRP localization., PMID:17897642

Borna disease virus blocks potentiation of presynaptic activity through inhibition of protein kinase C signaling., PMID:16552443

Involvement of Rho-kinase in inflammatory and neuropathic pain through phosphorylation of myristoylated alanine-rich C-kinase substrate (MARCKS)., PMID:15708490

The involvement of protein kinase C and actin filaments in cortical granule exocytosis in the rat., PMID:15695610

Identification of myristoylated alanine-rich C kinase substrate (MARCKS) in astrocytes., PMID:15574358

Identification of the chicken MARCKS phosphorylation site specific for differentiating neurons as Ser 25 using a monoclonal antibody and mass spectrometry., PMID:14998167

Immunoseparation of Prion protein-enriched domains from other detergent-resistant membrane fractions, isolated from neuronal cells., PMID:14741357

[Probing of the target molecules of Rho-kinase and its function in neuronal cells]., PMID:14727513

Myoblast migration is prevented by a calpain-dependent accumulation of MARCKS., PMID:14720464

Protein phosphorylation in neutrophils monitored with phosphospecific antibodies., PMID:14580883

2-pyrrolidinone induces a long-lasting facilitation of hippocampal synaptic transmission by enhancing alpha7 ACh receptor responses via a PKC pathway., PMID:14499485

Expression of MARCKS mRNA in lateral geniculate nucleus and visual cortex of normal and monocularly deprived macaque monkeys., PMID:12507329

The novel and specific Rho-kinase inhibitor (S)-(+)-2-methyl-1-[(4-methyl-5-isoquinoline)sulfonyl]-homopiperazine as a probing molecule for Rho-kinase-involved pathway., PMID:12191614

Inhibition of rho-kinase-induced myristoylated alanine-rich C kinase substrate (MARCKS) phosphorylation in human neuronal cells by H-1152, a novel and specific Rho-kinase inhibitor., PMID:12067241

Sustained phosphorylation of MARCKS in differentiating neurogenic regions during chick embryo development., PMID:11675128

Microglial signaling by amyloid beta protein through mitogen-activated protein kinase mediating phosphorylation of MARCKS., PMID:11496150

Apical accumulation of MARCKS in neural plate cells during neurulation in the chick embryo., PMID:11329360

Rho-associated kinase phosphorylates MARCKS in human neuronal cells., PMID:11162562

Datasheet

Document Download

Anti-MARCKS Antibody (R3H87).pdf

 

$ 220
Product specifications
50 μg 220 100 μg 350

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Anti-MARCKS Antibody (R3H87) [RHD85501]
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