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Anti-CD1c Antibody (R3H68)

Catalog #:   RHD81102 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG2b
Applications: ELISA, FCM, IHC
Accession: P29017
Overview

Catalog No.

RHD81102

Species reactivity

Human

Host species

Mouse

Isotype

IgG2b

Clonality

Monoclonal

Tested applications

ELISA: 1:10000, FCM: 1:200-1:400, IHC: 1:200-1:1000

Target

CD1c, CD1C, T-cell surface glycoprotein CD1c

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P29017

Applications

ELISA, FCM, IHC

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R3H68

Data Image
  • Flow Cytometry
    Flow cytometric analysis of Ramos cells using CD1C mouse mAb (green) and negative control (red).
  • Immunohistochemical
    Immunohistochemical analysis of paraffin-embedded human rectum cancer tissues using CD1C mouse mAb with DAB staining.
References

Effect of DNA methylation on inhibitor development in people with hemophilia A treated with FVIII concentrates., PMID:40502981

Effect of controlled human Plasmodium falciparum infection on B cell subsets in individuals with different levels of malaria immunity., PMID:40321757

Transcriptomic signatures in peripheral CD4+T-lymphocytes may reflect melanoma staging and immunotherapy responsiveness prior to ICI initiation., PMID:40226614

A novel monoclonal antibody against human thymic stromal lymphopoietin for the treatment of TSLP-mediated diseases., PMID:39726595

Prevalence of hybrid TLR4+M2 monocytes/macrophages in peripheral blood and lung of systemic sclerosis patients with interstitial lung disease., PMID:39635531

A randomized phase II clinical trial of stereotactic body radiation therapy (SBRT) and systemic pembrolizumab with or without intratumoral avelumab/ipilimumab plus CD1c (BDCA-1)+/CD141 (BDCA-3)+ myeloid dendritic cells in solid tumors., PMID:38954010

Exosomes multiplex profiling, a promising strategy for early diagnosis of laryngeal cancer., PMID:38902710

cDC2 plasticity and acquisition of a DC3-like phenotype mediated by IL-6 and PGE2 in a patient-derived colorectal cancer organoids model., PMID:38509863

Intratumoral administration of the immunologic adjuvant AS01B in combination with autologous CD1c (BDCA-1)+/CD141 (BDCA-3)+ myeloid dendritic cells plus ipilimumab and intravenous nivolumab in patients with refractory advanced melanoma., PMID:38212127

Vedolizumab Efficacy Is Associated With Decreased Intracolonic Dendritic Cells, Not Memory T Cells., PMID:37837660

Human IgMhiCD300a+ B Cells Are Circulating Marginal Zone Memory B Cells That Respond to Pneumococcal Polysaccharides and Their Frequency Is Decreased in People Living with HIV., PMID:37762055

Saponin-based adjuvants enhance antigen cross-presentation in human CD11c+ CD1c+ CD5- CD163+ conventional type 2 dendritic cells., PMID:37612044

Impaired Antitumor Immune Response in MYCN-amplified Neuroblastoma Is Associated with Lack of CCL2 Secretion and Poor Dendritic Cell Recruitment., PMID:36923280

Distribution of DC Subtypes: CD83+, DC-LAMP+, CD1a+, CD1c+, CD123+, and DC-SIGN+ in the Tumor Microenvironment of Endometrial Cancers-Correlation with Clinicopathologic Features., PMID:36768258

Longitudinal immune profiling after radiation-attenuated sporozoite vaccination reveals coordinated immune processes correlated with malaria protection., PMID:36591224

An immune risk score predicts progression-free survival of melanoma patients in South China receiving anti-PD-1 inhibitor therapy-a retrospective cohort study examining 66 circulating immune cell subsets., PMID:36569825

Deciphering the Immune Complexity in Esophageal Adenocarcinoma and Pre-Cancerous Lesions With Sequential Multiplex Immunohistochemistry and Sparse Subspace Clustering Approach., PMID:35663986

Development of a Phagocytosis-Dependent Gene Signature to Predict Prognosis and Response to Checkpoint Inhibition in Clear-Cell Renal Cell Carcinoma., PMID:35651604

Mass Cytometric Analysis of Early-Stage Mycosis Fungoides., PMID:35406628

Intravenous Immunoglobulin Therapy Restores the Quantity and Phenotype of Circulating Dendritic Cells and CD4+ T Cells in Children With Acute Kawasaki Disease., PMID:35222381

Conventional Type 1 Dendritic Cells (cDC1) in Human Kidney Diseases: Clinico-Pathological Correlations., PMID:34054804

Implication of TIGIT+ human memory B cells in immune regulation., PMID:33750787

Non-permissive human conventional CD1c+ dendritic cells enable trans-infection of human primary renal tubular epithelial cells and protect BK polyomavirus from neutralization., PMID:33592065

Exploiting CD1-restricted T cells for clinical benefit., PMID:33582549

Differential Changes in Inflammatory Mononuclear Phagocyte and T-Cell Profiles within Psoriatic Skin during Treatment with Guselkumab vs. Secukinumab., PMID:33524368

Subjects at-risk for future development of rheumatoid arthritis demonstrate a PAD4-and TLR-dependent enhanced histone H3 citrullination and proinflammatory cytokine production in CD14hi monocytes., PMID:33310262

Intratumoral Combinatorial Administration of CD1c (BDCA-1)+ Myeloid Dendritic Cells Plus Ipilimumab and Avelumab in Combination with Intravenous Low-Dose Nivolumab in Patients with Advanced Solid Tumors: A Phase IB Clinical Trial., PMID:33182610

Rheumatoid arthritis synovial microenvironment induces metabolic and functional adaptations in dendritic cells., PMID:32557565

Identification of unique clusters of T, dendritic, and innate lymphoid cells in the peritoneal fluid of ovarian cancer patients., PMID:32524661

Differential Expression of IgM and IgD Discriminates Two Subpopulations of Human Circulating IgM+IgD+CD27+ B Cells That Differ Phenotypically, Functionally, and Genetically., PMID:32435242

Immunologic timeline of Ebola virus disease and recovery in humans., PMID:32434986

Mass Cytometry Analysis Reveals Complex Cell-State Modifications of Blood Myeloid Cells During HIV Infection., PMID:31824485

NR4A Expression by Human Marginal Zone B-Cells., PMID:31614541

Human B1 Cells are the Main Blood Group A-Specific B Cells That Have a Moderate Correlation With Anti-A Antibody Titer., PMID:31432639

Myeloid Dendritic Cells Are Enriched in Lymph Node Tissue of Early Rheumatoid Arthritis Patients but not in At Risk Individuals., PMID:31330824

Natural Immunity to HIV is associated with Low BLyS/BAFF levels and low frequencies of innate marginal zone like CD1c+ B-cells in the genital tract., PMID:31173604

Citrullination Controls Dendritic Cell Transdifferentiation into Osteoclasts., PMID:31019059

Expansion and activation of distinct central memory T lymphocyte subsets in complex regional pain syndrome., PMID:30885223

CD1b presents self and Borrelia burgdorferi diacylglycerols to human T cells., PMID:30854633

Immune Cell Composition in Human Non-small Cell Lung Cancer., PMID:30774636

Identification of Human B-1 Helper T Cells With a Th1-Like Memory Phenotype and High Integrin CD49d Expression., PMID:30061889

Adaptive Regulation of Osteopontin Production by Dendritic Cells Through the Bidirectional Interaction With Mesenchymal Stromal Cells., PMID:29910810

CLEC10A Is a Specific Marker for Human CD1c+ Dendritic Cells and Enhances Their Toll-Like Receptor 7/8-Induced Cytokine Secretion., PMID:29755453

Formation of Immune Complexes with a Tetanus-Derived B Cell Epitope Boosts Human T Cell Responses to Covalently Linked Peptides in an Ex Vivo Blood Loop System., PMID:29752315

Decreased IgG4 ACPA levels in responders and increased CD1c+ classical dendritic cells in non-responders of patients with rheumatoid arthritis under therapy., PMID:29502227

A Subset of Human Autoreactive CD1c-Restricted T Cells Preferentially Expresses TRBV4-1+ TCRs., PMID:29237773

Arterial immune protein expression demonstrates the complexity of immune responses in Kawasaki disease arteritis., PMID:28707750

Folliculotropic Mycosis Fungoides with Skewed T-cell Receptor CDR3 Motif: Suggestive of Lipid-antigen Selection?, PMID:28597017

Dendritic Cells Display Subset and Tissue-Specific Maturation Dynamics over Human Life., PMID:28329707

The TH2-polarizing function of atopic interleukin 17 receptor B-positive dendritic cells up-regulated by lipopolysaccharide., PMID:28132739

Datasheet

Document Download

Anti-CD1c Antibody (R3H68).pdf

 

$ 220
Product specifications
50 μg 220 100 μg 350

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Anti-CD1c Antibody (R3H68) [RHD81102]
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