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Anti-CD38/ADPRC 1 Antibody (R3H61)

Catalog #:   RHD80809 Specific References (49) DATASHEET
Host species: Mouse
Isotype: IgG1
Applications: IHC
Accession: P28907
Overview

Catalog No.

RHD80809

Species reactivity

Human

Host species

Mouse

Isotype

IgG1

Clonality

Monoclonal

Tested applications

IHC: 1:100-1:200

Target

Cyclic ADP-ribose hydrolase 1, ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1, cADPr hydrolase 1, 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase, T10, 2'-phospho-cyclic-ADP-ribose transferase, CD38, ADPRC 1, ADP-ribosyl cyclase 1, 2'-phospho-ADP-ribosyl cyclase

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P28907

Applications

IHC

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R3H61

Data Image
  • Immunohistochemical
    Immunohistochemical analysis of paraffin-embedded human breast cancer tissues using CD38 mouse mAb with DAB staining.
  • Immunohistochemical
    Immunohistochemical analysis of paraffin-embedded human renal cancer tissues using CD38 mouse mAb with DAB staining.
  • Immunohistochemical
    Immunohistochemical analysis of paraffin-embedded human gastric cancer tissues using CD38 mouse mAb with DAB staining.
References

Daratumumab (anti-CD38)- and elotuzumab (anti-SLAMF7)-based treatments for refractory POEMS syndrome: a single-center case series., PMID:40528367

Retreatment With Anti-CD38-Based Combinations in Multiple Myeloma in Real-Life: Results From the Emmy Cohort Study., PMID:40518372

PSGL-1 is a phagocytosis checkpoint that enables tumor escape from macrophage clearance., PMID:40512837

Efficacy and safety of anti-CD38 monoclonal antibodies in patients with newly diagnosed multiple myeloma: an updated systematic review and meta-analysis based on randomized controlled trials., PMID:40501427

Daratumumab for Treatment of Acute Antibody-Mediated Rejection in a Pediatric Kidney Transplant Recipient., PMID:40490910

Antibody-mediated ratiometric delivery of FLT3 and CDK4/6 dual inhibitors for targeted treatment of acute myeloid leukemia., PMID:40482924

Comparative Efficacy and Safety of Daratumumab-Integrated Quadruple Therapy Versus Triple Therapy in Transplant-Eligible Newly Diagnosed Multiple Myeloma: A Systematic Review and Meta-Analysis., PMID:40473556

Peripheral memory B cell population maintenance and long-term survival after perioperative chemoimmunotherapy in NSCLC (NADIM trial)., PMID:40468805

FDA Approval Summary: Idecabtagene Vicleucel for the Treatment of Triple-Class Exposed, Relapsed or Refractory Multiple Myeloma., PMID:40465403

Functional multiomics reveals genetic and pharmacologic regulation of surface CD38 in multiple myeloma., PMID:40453054

A ROS-Responsive Dual-Targeting Drug Nanocarrier Serving as a GSI Synergist and Ferroptosis Sensitizer for T-Cell Acute Lymphoblastic Leukemia., PMID:40448620

Population Pharmacokinetics for Belantamab Mafodotin Monotherapy and Combination Therapies in Patients with Relapsed/Refractory Multiple Myeloma., PMID:40447948

Targeting CD38 in Antibody-Mediated Rejection., PMID:40444214

Real-World Treatment Patterns and Survival Outcomes of Patients with Relapsed/Refractory Multiple Myeloma Treated with a Selinexor-Containing Triplet-Based Regimen., PMID:40422527

Reduced immune response to SARS-CoV-2 infection in the elderly after 6 months., PMID:40416973

Daratumumab monotherapy as a desensitization strategy prior to cardiac transplantation., PMID:40407767

Practice-changing updates on multiple myeloma: highlights from the 2024 ASH annual meeting., PMID:40361170

Phase 1 study of talquetamab, a humanized GPRC5D x CD3 bispecific antibody, in Japanese patients with relapsed/refractory MM., PMID:40343678

Real-world analysis of treatment patterns, effectiveness, and safety of daratumumab-based regimens in Chinese patients with newly diagnosed or relapsed/refractory multiple myeloma., PMID:40335949

CD38-targeted attenuated interferon alpha immunocytokine activates both innate and adaptive immune cells to drive anti-tumor activity., PMID:40315226

Effect of felzartamab on the molecular phenotype of antibody-mediated rejection in kidney transplant biopsies., PMID:40301559

Kinetics of the humoral and cellular immune response up to 1 year from mpox virus infection., PMID:40294869

Peripheral T-cell subset activation in NMDAR encephalitis: Insights into pathogenesis and biomarker potential for disease monitoring., PMID:40288549

Real-World Data on the Efficacy of Daratumumab in Patients with Relapsed/Refractory Multiple Myeloma and Amplification 1q., PMID:40282438

Consensus Guidelines and Recommendations for The CD38 Monoclonal Antibody-based Quadruplet Therapy and Management in Clinical Practice for Newly Diagnosed Multiple Myeloma: From the Pan-Pacific Multiple Myeloma Working Group., PMID:40271095

Multiple myeloma with 1q gain/amplification exhibits reduced CD38 expression via interleukin-6 receptor overexpression., PMID:40259818

Targeting CD38 immunometabolic checkpoint improves metabolic fitness and cognition in a mouse model of Alzheimer's disease., PMID:40254603

BCMA CAR T cells in a patient with relapsing idiopathic inflammatory myositis after initial and repeat therapy with CD19 CAR T cells., PMID:40245922

The de novo DNA methyltransferase 3B is a novel epigenetic regulator of MYC in multiple myeloma, representing a promising therapeutic target to counter relapse., PMID:40241199

Treatment refractoriness and response rates in patients with relapsed/refractory multiple myeloma: a retrospective analysis of real-world data., PMID:40199119

Efficacy and Safety of Quadruplet Therapy in Newly Diagnosed Transplant-Eligible Multiple Myeloma: A Systematic Review and Meta-Analysis., PMID:40176408

Impact of Protein Kinase C Activation and Monoclonal Antibodies on Immune Checkpoint Regulation and B Cell Function in Patients with Chronic Lymphocytic Leukemia., PMID:40149717

A systematic review and meta-analysis of phase III randomized controlled trials to assess the risk of pneumonia, URTIs, and VTE in multiple myeloma patients treated with isatuximab., PMID:40124649

Outcomes of Newly Diagnosed Multiple Myeloma Patients Requiring Dialysis., PMID:40122729

The effects of intragraft CD38+ B cell on chronic active antibody mediated rejection in kidney transplantation., PMID:40111715

T-cell activation and senescence in asymptomatic HIV/Leishmania infantum co-infection., PMID:40096173

Real-World Outcomes of Newly Diagnosed Multiple Myeloma Patients Treated Before the Era of Anti-CD38 Antibodies: The EMMY Cohort From 2017 to 2020., PMID:40087879

Early daratumumab therapy improves renal outcomes in newly diagnosed myeloma patients admitted with kidney injury., PMID:40085948

How First-Line Therapy is Changing in non-Transplant Eligible Multiple Myeloma Patients., PMID:40084107

Novelties on Multiple Myeloma from the Main 2024 Hematology Conferences., PMID:40084104

How First-Line Therapy is Changing in Transplant-Eligible Multiple Myeloma Patients., PMID:40084095

Evolution of Survival in Patients with Multiple Myeloma over Two Decades: A Real-World Experience from a Medium-Level Hospital., PMID:40075641

Efficacy of Combined CD38 and PD1 Inhibition with Isatuximab and Cemiplimab for Relapsed/Refractory NK/T-Cell Lymphoma., PMID:40073374

Gene-modified NK cells expressing CD64 and preloaded with HIV-specific BNAbs target autologous HIV-1-infected CD4+ T cells by ADCC., PMID:40073240

CD38 in the pathobiology of cutaneous T-cell lymphoma and the potential for combination therapeutic intervention., PMID:40057636

CD31 + naïve T cells associate with immunosenescence and responsiveness to multiple vaccines in older adults., PMID:40055790

Treatment of Multiple Myeloma in Patients Refractory to Daratumumab/Anti-CD38 Monoclonal Antibodies: A Systematic Review., PMID:40052837

Outcomes of triple-class refractory multiple myeloma patients at a single clinic: A retrospective study., PMID:40037111

Monoclonal anti-CD38 therapy in human myeloma: retrospects and prospects., PMID:40013150

Datasheet
$ 220
Product specifications
50 μg 220 100 μg 350

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Anti-CD38/ADPRC 1 Antibody (R3H61) [RHD80809]
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