Catalog No.
RHD73103
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
ELISA: 1:10000, FCM: 1:200-1:400, IF: 1:200-1:1000, IHC: 1:200-1:1000, WB: 1:500-1:2000
Target
Serum paraoxonase/arylesterase 1, PON, Aromatic esterase 1, PON1, Serum aryldialkylphosphatase 1, PON 1, K-45, A-esterase 1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P27169
Applications
ELISA, FCM, IF, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3H22
Disease response in rheumatoid arthritis across four biologic therapies associates with improvement in paraoxonase-1 activity and oxylipins., PMID:39461874
Risk stratification analysis of recurrent myocardial infarction in Indian population using inflammatory, lipid, thrombotic and extracellular matrix remodeling markers., PMID:39351476
Biological markers of high risk of thrombotic recurrence in patients with antiphospholipid syndrome: A literature review., PMID:39094811
Propolis Reduces Inflammation and Dyslipidemia Caused by High-Cholesterol Diet in Mice by Lowering ADAM10/17 Activities., PMID:38931216
Improvement of high-density lipoprotein atheroprotective properties in patients with systemic lupus erythematosus after belimumab treatment., PMID:38514392
Association of PON1, APOE and SDF-1 Gene Polymorphisms with Treatment Response to Intravitreal Anti-VEGF Treatment in Patients with Retinal Vein Occlusion., PMID:37997789
mTOR-dependent loss of PON1 secretion and antiphospholipid autoantibody production underlie autoimmunity-mediated cirrhosis in transaldolase deficiency., PMID:37742509
Acute phase proteins and total antioxidant capacity in free-roaming cats infected by pathogenic leptospires., PMID:37679743
Power doppler ultrasound signal predicts abnormal HDL function in patients with rheumatoid arthritis., PMID:36828925
Abnormal paraoxonase-1 (PON1) enzyme activity in idiopathic inflammatory myopathies., PMID:34698804
High-resolution serum proteome trajectories in COVID-19 reveal patient-specific seroconversion., PMID:34232570
Genetic Variability of Antioxidative Mechanisms and Cardiotoxicity after Adjuvant Radiotherapy in HER2-Positive Breast Cancer Patients., PMID:33425072
Identification of Protein Carbonyls (PCOs) in Canine Serum by Western Blot Technique and Preliminary Evaluation of PCO Concentration in Dogs With Systemic Inflammation., PMID:33363227
Suppression of inflammatory arthritis in human serum paraoxonase 1 transgenic mice., PMID:33033318
ABCA1 gene R1587K polymorphism could be associated with metabolic syndrome and increased plasma triglyceride concentration in adults from northern Mexico., PMID:32686443
Cladribine Treatment Improved Homocysteine Metabolism and Increased Total Serum Antioxidant Activity in Secondary Progressive Multiple Sclerosis Patients., PMID:32256946
Increased Levels of Plasma Tumor Necrosis Factor-α Mediate Schizophrenia Symptom Dimensions and Neurocognitive Impairments and Are Inversely Associated with Natural IgM Directed to Malondialdehyde and Paraoxonase 1 Activity., PMID:32040834
Efficient Site-Specific Prokaryotic and Eukaryotic Incorporation of Halotyrosine Amino Acids into Proteins., PMID:31994864
5α,6α-Epoxyphytosterols and 5α,6α-Epoxycholesterol Increase Oxidative Stress in Rats on Low-Cholesterol Diet., PMID:31827670
Schizophrenia phenomenology comprises a bifactorial general severity and a single-group factor, which are differently associated with neurotoxic immune and immune-regulatory pathways., PMID:31734647
Zinc source modulates zootechnical characteristics, intestinal features, humoral response, and paraoxonase (PON1) activity in broilers., PMID:31422525
Paraoxonases (PON) 1, 2, and 3 Polymorphisms and PON-1 Activities in Patients with Sickle Cell Disease., PMID:31366068
Three patients with probable aerotoxic syndrome., PMID:31092058
Association between activity and genotypes of paraoxonase1 L55M (rs854560) increases the disease activity of rheumatoid arthritis through oxidative stress., PMID:30506510
Relationship between serum anti-Leishmania antibody levels and acute phase proteins in dogs with canine leishmaniosis., PMID:30197018
Remodeling of the HDL proteome with treatment response to abatacept or adalimumab in the AMPLE trial of patients with rheumatoid arthritis., PMID:29886354
Anti-High-Density Lipoprotein Antibodies and Antioxidant Dysfunction in Immune-Driven Diseases., PMID:29740582
Antibodies against HDL Components in Ischaemic Stroke and Coronary Artery Disease., PMID:29723873
Association between the oxidative status, Vitamin D levels and respiratory function in asthmatic children., PMID:29411726
Lipoprotein apheresis affects lipoprotein particle subclasses more efficiently compared to the PCSK9 inhibitor evolocumab, a pilot study., PMID:29398508
Serum Levels of Anti-PON1 and Anti-HDL Antibodies as Potential Biomarkers of Premature Atherosclerosis in Systemic Lupus Erythematosus., PMID:29044294
The effect of vitamin E, L-carnitine, and ginger on production traits, immune response, and antioxidant status in two broiler strains exposed to chronic heat stress., PMID:28963619
Extended-release niacin increases anti-apolipoprotein A-I antibodies that block the antioxidant effect of high-density lipoprotein-cholesterol: the EXPLORE clinical trial., PMID:27891663
Anti-inflammatory treatment improves high-density lipoprotein function in rheumatoid arthritis., PMID:27852695
Expression and purification of biologically active recombinant human paraoxonase 1 from a Drosophila S2 stable cell line., PMID:27838376
Processes of plasma protein N-homocysteinylation in multiple sclerosis., PMID:27671515
Effects of pomegranate juice consumption on oxidative stress in patients with type 2 diabetes: a single-blind, randomized clinical trial., PMID:27633135
Lipid peroxidation as risk factor for endothelial dysfunction in antiphospholipid syndrome patients., PMID:27562033
Antibodies to paraoxonase 1 are associated with oxidant status and endothelial activation in rheumatoid arthritis., PMID:27520507
Improvement of High-Density Lipoprotein Function in Patients With Early Rheumatoid Arthritis Treated With Methotrexate Monotherapy or Combination Therapies in a Randomized Controlled Trial., PMID:27483410
The Effects of Levetiracetam on Cerebrospinal Fluid and Plasma NPY and GAL, and on the Components of Stress Response System, hs-CRP, and S100B Protein in Serum of Patients with Refractory Epilepsy., PMID:27352343
The impact of levothyroxine sodium treatment on oxidative stress in Hashimoto's thyroiditis., PMID:26951600
Paraoxonase 1 Activity Is Modulated by the rs662 Polymorphism and IgG Anti-High-Density Lipoprotein Antibodies in Patients With Rheumatoid Arthritis: Potential Implications for Cardiovascular Disease., PMID:26815637
Screening for potential serum biomarkers in rat mesangial proliferative nephritis., PMID:26791873
Low High-Density Lipoprotein and Risk of Myocardial Infarction., PMID:26692765
The relationship between oxidative stress and autoimmunity in Hashimoto's thyroiditis., PMID:26340971
Impaired Antiatherogenic Functions of High-density Lipoprotein in Patients with Ankylosing Spondylitis., PMID:26233507
Paraoxonase-1 and oxidized lipoprotein lipids. The Cardiovascular Risk in Young Finns Study., PMID:26091975
[The protective effect of regulation of paraoxonase 1 gene on liver oxidative stress injury induced by dichlorvos poisoning in mice]., PMID:25891459
Paraoxonase 1 activity and level of antibodies directed against oxidized low density lipoproteins in a group of an elderly population in Poland - PolSenior study., PMID:25459919
For research use only. Not for human or drug use.
