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Anti-CD27 Antibody (R3H18)

Catalog #:   RHD72202 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG1
Applications: ELISA, FCM
Accession: P26842
Overview

Catalog No.

RHD72202

Species reactivity

Human

Host species

Mouse

Isotype

IgG1

Clonality

Monoclonal

Tested applications

ELISA: 1:10000, FCM: 1:200-1:400

Target

CD27L receptor, TNFRSF7, T14, CD27 antigen, Tumor necrosis factor receptor superfamily member 7, CD27, T-cell activation antigen CD27

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P26842

Applications

ELISA, FCM

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R3H18

Data Image
  • Flow Cytometry
    Flow cytometric analysis of HL-60 cells using CD27 mouse mAb (green) and negative control (red).
References

Monitoring anti-Rituximab antibodies in myasthenia gravis affects the time to event during Rituximab treatment., PMID:40488894

Adaptive immune changes in colorectal cancer: a focus on T and B cell activation genes., PMID:40484866

Peripheral memory B cell population maintenance and long-term survival after perioperative chemoimmunotherapy in NSCLC (NADIM trial)., PMID:40468805

Toll-like receptor engaged in activation and osteoimmuno-cytokines production by unswitched memory B cells during periodontitis., PMID:40455294

Long-Term Effectiveness and Safety of Rituximab in Neuromyelitis Optica Spectrum Disorder: A 5-Year Observational Study., PMID:40442445

Interferon signatures fuel B cell hyperactivity and plasmablast expansion in systemic lupus erythematosus., PMID:40424895

The CD70-CD27 axis in cancer immunotherapy: Predictive biomarker and therapeutic target., PMID:40388162

Microbead-based synthetic niches for in vitro expansion and differentiation of human naïve B-cells., PMID:40385534

Comprehensive analysis of B cell repopulation in ocrelizumab-treated patients with multiple sclerosis by mass cytometry and proteomics., PMID:40322080

Effect of controlled human Plasmodium falciparum infection on B cell subsets in individuals with different levels of malaria immunity., PMID:40321757

Influence of polyfunctional Tbet+ T cells on specific clinical events in chronic lymphocytic leukaemia., PMID:40313965

CD70-Targeted [18F]RCCB6 Immuno-PET/CT Imaging in Patients with Nasopharyngeal Carcinoma: A Proof-of-Concept Study., PMID:40306966

Treatment Efficacy and Molecular Dynamics of Neoadjuvant Durvalumab and Olaparib in Resectable Urothelial Bladder Cancer: The NEODURVARIB Trial., PMID:40298406

The role of double-negative B cells in the pathogenesis of systemic lupus erythematosus., PMID:40274006

Desensitization With Proteasome Inhibition and Costimulation Blockade Modulates the Xenoreactive Humoral Response in Nonhuman Primate Xenotransplantation., PMID:40259710

Unsupervised machine learning identifies distinct systemic lupus erythematosus patient endotypes with differential response to belimumab., PMID:40244828

CD70 recruitment to the immunological synapse is dependent on CD20 in B cells., PMID:40232798

Phenotypic heterogeneity defines B cell responses to repeated SARS-CoV-2 exposures through vaccination and infection., PMID:40222009

Long-lasting antibody B-cell responses to SARS-CoV-2 three years after the onset of the pandemic., PMID:40173043

Two distinct durable human class-switched memory B cell populations are induced by vaccination and infection., PMID:40173042

Impact of Protein Kinase C Activation and Monoclonal Antibodies on Immune Checkpoint Regulation and B Cell Function in Patients with Chronic Lymphocytic Leukemia., PMID:40149717

Aberrant Lower CD6 Expression on Peripheral B Cells Associated With Liver/Kidney Injury and Autoantibody Production of Systemic Lupus Erythematosus Patients., PMID:40134233

Comprehensive Phenotyping and Cytokine Production of Circulating B Cells Associate Resting Memory B Cells With Early Antibody-mediated Rejection in Kidney Transplant Recipients., PMID:40124243

Single-cell RNA-sequencing reveals cellular heterogeneity and immune microenvironment characteristics between ocular adnexal mucosa-associated lymphoid lymphoma and IgG4-related ophthalmic disease., PMID:40078987

IL-4 alters TLR7-induced B cell developmental program in lupus., PMID:40068727

CD8α and CD70 mark human natural killer cell populations which differ in cytotoxicity., PMID:40046047

Development and Preclinical Evaluation of [64Cu]Cu-NOTA-ABDB6: A CD70 and Albumin Dual-Binding Tracer with Improved Pharmacokinetics., PMID:40015924

Spatially Resolved, Multiregion Proteomics for Prediction of Immunotherapy Outcome in Deficient Mismatch Repair Metastatic Colorectal Cancer., PMID:39969975

Anti-myeloperoxidase IgM B cells in anti-neutrophil cytoplasmic antibody-associated vasculitis., PMID:39939347

Rheumatoid Arthritis Related B-Cell Changes Are Found Already in the Risk-RA Phase., PMID:39931747

BNT162b2 mRNA vaccination affects the gut microbiome composition of patients with follicular lymphoma and chronic lymphocytic leukemia., PMID:39930533

Evaluation of B cell related markers and autoantibodies in rheumatoid arthritis patients treated with abatacept., PMID:39925810

A self-activated and protective module enhances the preclinical performance of allogeneic anti-CD70 CAR-T cells., PMID:39906740

Myricetin exposure reduces PC differentiation in vitro in primary human B cells., PMID:39875809

Maternal obesity associates with altered humoral immunity in blood and colostrum., PMID:39870213

Changes in and Potential Mechanisms of Circulating IgA+CD27-Class-Switched Memory B Cells in Patients With Allergic Rhinitis., PMID:39867643

The Role of Dendritic Cells in Adaptive Immune Response Induced by OVA/PDDA Nanoparticles., PMID:39852855

Bivalent OX40 Aptamer and CpG as Dual Agonists for Cancer Immunotherapy., PMID:39841045

Novel Sarcoidosis Epitope Augments MHCII, CD80/CD86 Expression, Promotes B-Cell Differentiation and IgG Production., PMID:39836049

Genetically reprogrammed exosomes for immunotherapy of acute myeloid leukemia., PMID:39815621

Hypomorphic RAG2 Deficiency Promotes Selection of Self-Reactive B Cells., PMID:39812873

Longitudinal monitoring of class-switched memory-B cell proportions identifies plausible germinal center failure in patients with suspected immune disorders., PMID:39791256

Subset of DN Memory B Cells Expressing Low Levels of Inhibitory Receptor BTLA Is Enriched in SLE Patients., PMID:39768154

Induction of interleukin 21 receptor expression via enhanced intracellular metabolism in B cells and its relevance to the disease activity in systemic lupus erythematosus., PMID:39740932

PIgR Autoantibody-abundant Circulating Vesicles Contributes to Biliary Injury in Biliary Atresia., PMID:39733605

Donor HLA-DQ reactive B cells clonally expand under chronic immunosuppression and include atypical CD21 low CD27 - B cells with high-avidity germline B-cell receptors., PMID:39713394

B Cell Receptor Repertoire Analysis of the CD21lo B Cell Compartment in Healthy Individuals, Patients With Sjögren's Disease, and Patients With Radiographic Axial Spondyloarthritis., PMID:39707660

Herpesvirus Antibodies Are Correlated With Greater Expression of p16 in the T Cells of Humans., PMID:39703789

Characterization of anti-asialo-GM1 monoclonal antibody., PMID:39693935

Kir6.1, a component of an ATP-sensitive potassium channel, regulates natural killer cell development., PMID:39687626

Datasheet

Document Download

Anti-CD27 Antibody (R3H18).pdf

 

$ 220
Product specifications
50 μg 220 100 μg 350

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Anti-CD27 Antibody (R3H18) [RHD72202]
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