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Anti-BRD2 Antibody (R3G74)

Catalog #:   RHD67103 Specific References (19) DATASHEET
Host species: Mouse
Isotype: IgG2b
Applications: ELISA, FCM, WB
Accession: P25440
Overview

Catalog No.

RHD67103

Species reactivity

Human, Rat

Host species

Mouse

Isotype

IgG2b

Clonality

Monoclonal

Tested applications

ELISA: 1:10000, FCM: 1:200-1:400, WB: 1:500-1:2000

Target

Really interesting new gene 3 protein, KIAA9001, O27.1.1, BRD2, RING3, Bromodomain-containing protein 2

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P25440

Applications

ELISA, FCM, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R3G74

Data Image
  • Flow Cytometry
    Flow cytometric analysis of Hela cells using BRD2 mouse mAb (green) and negative control (red).
  • Western blot
    Western blot analysis using BRD2 mouse mAb against C6 (1) and Hela (2) cell lysate.
References

BRD2 promotes antibody class switch recombination by facilitating DNA repair in collaboration with NIPBL., PMID:38567724

cFLIP suppression and DR5 activation sensitize senescent cancer cells to senolysis., PMID:36414711

Serum BRD2 autoantibody in hepatocellular carcinoma and its detection using mimotope peptide‑conjugated BSA., PMID:36321789

BRD2 inhibition blocks SARS-CoV-2 infection by reducing transcription of the host cell receptor ACE2., PMID:35027731

PD-L1 is upregulated via BRD2 in head and neck squamous cell carcinoma models of acquired cetuximab resistance., PMID:34346116

Three-dimensional CRISPR screening reveals epigenetic interaction with anti-angiogenic therapy., PMID:34267311

BRD2 inhibition blocks SARS-CoV-2 infection by reducing transcription of the host cell receptor ACE2., PMID:33501440

Controlled Delivery of BET-PROTACs: In Vitro Evaluation of MZ1-Loaded Polymeric Antibody Conjugated Nanoparticles in Breast Cancer., PMID:33086530

BRD4 bimodal binding at promoters and drug-induced displacement at Pol II pause sites associates with I-BET sensitivity., PMID:31266503

Bromodomain and extra-terminal domain bromodomain inhibition prevents synovial inflammation via blocking IκB kinase-dependent NF-κB activation in rheumatoid fibroblast-like synoviocytes., PMID:26324948

BET inhibitor OTX015 targets BRD2 and BRD4 and decreases c-MYC in acute leukemia cells., PMID:25989842

BET bromodomains regulate transforming growth factor-β-induced proliferation and cytokine release in asthmatic airway smooth muscle., PMID:25697361

The ARID domain of the H3K4 demethylase RBP2 binds to a DNA CCGCCC motif., PMID:18270511

E mu-BRD2 transgenic mice develop B-cell lymphoma and leukemia., PMID:14563639

Reproductive cycle regulation of nuclear import, euchromatic localization, and association with components of Pol II mediator of a mammalian double-bromodomain protein., PMID:12145330

Identification and cloning of an 85-kDa protein homologous to RING3 that is upregulated in proliferating endothelial cells., PMID:11502199

Stimulation of p85/RING3 kinase in multiple organs after systemic administration of mitogens into mice., PMID:9528865

Rubella vaccine in the People's Republic of China., PMID:4001739

Studies on the reactogenicity and immunogenicity of the BRD-2 and RA27/3 live attenuated rubella vaccines., PMID:6531968

Datasheet

Document Download

Anti-BRD2 Antibody (R3G74).pdf

 

$ 220
Product specifications
50 μg 220 100 μg 350

Contact Information

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For research use only. Not for human or drug use.

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Anti-BRD2 Antibody (R3G74) [RHD67103]
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