Catalog No.
RHD64607
Species reactivity
Human
Host species
Mouse
Isotype
IgG2b
Clonality
Monoclonal
Tested applications
ELISA: 1:10000, FCM: 1:200-1:400
Target
DNA-directed RNA polymerase II subunit A, RNA-directed RNA polymerase II subunit RPB1, RNA polymerase II subunit B1, POLR2A, POLR2, DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase III largest subunit
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P24928
Applications
ELISA, FCM
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3G62
Genetic determinants of proteomic aging., PMID:40287427
Reliable detection of RNA in hippocampus sections of mice by FISH up to a post-mortem delay of 24 h., PMID:38582805
Novel Anti-B-cell Maturation Antigen Alpha-Amanitin Antibody-drug Conjugate HDP-101 Shows Superior Activity to Belantamab Mafodotin and Enhanced Efficacy in Deletion 17p Myeloma Models., PMID:38260385
Combined Wee1 and EGFR inhibition reveals synergistic antitumor effect in esophageal squamous cell carcinoma., PMID:37279554
Targeted immunotherapy for HER2-low breast cancer with 17p loss., PMID:33568521
Quantitative analysis of HER2 mRNA expression by RNA in situ hybridization in canine mammary gland tumors: Comparison with immunohistochemistry analysis., PMID:32059046
Novel Antibody-Drug Conjugate with Anti-CD26 Humanized Monoclonal Antibody and Transcription Factor IIH (TFIIH) Inhibitor, Triptolide, Inhibits Tumor Growth via Impairing mRNA Synthesis., PMID:31398954
BRAF inhibition sensitizes melanoma cells to α-amanitin via decreased RNA polymerase II assembly., PMID:31123282
Heterozygous deletion of chromosome 17p renders prostate cancer vulnerable to inhibition of RNA polymerase II., PMID:30349055
RNAscope in situ hybridization confirms mRNA integrity in formalin-fixed, paraffin-embedded cancer tissue samples., PMID:29212158
TP53 loss creates therapeutic vulnerability in colorectal cancer., PMID:25901683
Nuclear localization of CD26 induced by a humanized monoclonal antibody inhibits tumor cell growth by modulating of POLR2A transcription., PMID:23638030
Using ChIP-chip technology to reveal common principles of transcriptional repression in normal and cancer cells., PMID:18347325
For research use only. Not for human or drug use.
