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Anti-FSHR Antibody (R3G52)

Catalog #:   RHD61001 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG1
Applications: ELISA, FCM
Accession: P23945
Overview

Catalog No.

RHD61001

Species reactivity

Human

Host species

Mouse

Isotype

IgG1

Clonality

Monoclonal

Tested applications

ELISA: 1:10000, FCM: 1:200-1:400

Target

Follitropin receptor, LGR1, Follicle-stimulating hormone receptor, FSHR, FSH-R

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P23945

Applications

ELISA, FCM

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R3G52

Data Image
  • Flow Cytometry
    Flow cytometric analysis of Hela cells using FSHR mouse mAb (green) and negative control (red).
References

FSH exacerbates bone loss by promoting osteoclast energy metabolism through the CREB-MDH2-NAD+ axis., PMID:39880362

Immunization with OPN5 increased seasonal degradation of reproductive activity in Magang ganders., PMID:39754930

Active immunization with a novel recombinant GnRH vaccine inhibits reproductive function in male goats., PMID:39708581

Gene-dose-dependent reduction of Fshr expression improves spatial memory deficits in Alzheimer's mice., PMID:39548323

The occurrence of luteinizing hormone-like molecule and its receptor in the blue swimming crab, Portunus pelagicus., PMID:39366546

Antibody fragments targeting the extracellular domain of follicular stimulating hormone receptor for contraception in male dogs and cats., PMID:38875921

Follicle-stimulating hormone receptor expression in advanced atherosclerotic plaques., PMID:38702476

An intracellular VHH targeting the Luteinizing Hormone receptor modulates G protein-dependent signaling and steroidogenesis., PMID:38621656

FSH Is Responsible for Androgen Deprivation Therapy-Associated Atherosclerosis in Mice by Exaggerating Endothelial Inflammation and Monocyte Adhesion., PMID:38205641

Combined Multiplexed Phage Display, High-Throughput Sequencing, and Functional Assays as a Platform for Identifying Modulatory VHHs Targeting the FSHR., PMID:37958944

A single-domain intrabody targeting the follicle-stimulating hormone receptor impacts FSH-induced G protein-dependent signalling., PMID:37923554

Siglec-7 glyco-immune binding mAbs or NK cell engager biologics induce potent antitumor immunity against ovarian cancers., PMID:37910620

FSH and ApoE4 contribute to Alzheimer's disease-like pathogenesis via C/EBPβ/δ-secretase in female mice., PMID:37852961

Impaired Testicular Function without Altering Testosterone Concentration Using an Anti-Follicular-Stimulating Hormone Receptor (Anti-FSHr) Single-Chain Variable Fragment (scFv) in Long-Tailed Macaques (Macaca fascicularis)., PMID:37508065

Inadequate detection of the FSHR complicates future research on extragonadal FSHR localization., PMID:36875462

A mAb against surface-expressed FSHR engineered to engage adaptive immunity for ovarian cancer immunotherapy., PMID:36509287

Effects of dietary organic acids and probiotics on laying performance, egg quality, serum antioxidants and expressions of reproductive genes of laying ducks in the late phase of production., PMID:36240638

Two complementary approaches for efficient isolation of Sertoli cells for transcriptomic analysis., PMID:36158203

TSH receptor antibodies (TRAb) - A potential new biomarker for endometriosis., PMID:36152376

Effects of active immunization against a 13-amino acid receptor-binding epitope of FSHβ on fertility regulation in female mice., PMID:35772190

Follicle stimulating hormone promotes production of renin through its receptor in juxtaglomerular cells of kidney., PMID:35501878

Case report: Birth achieved after effective ovarian stimulation combined with dexamethasone in a patient with resistant ovary syndrome., PMID:35392972

Changes in Expression of Specific mRNA Transcripts after Single- or Re-Irradiation in Mouse Testes., PMID:35052491

Soya saponin improves egg-laying performance and immune function of laying hens., PMID:34986871

Autoimmunity to the Follicle-Stimulating Hormone Receptor (FSHR) and Luteinizing Hormone Receptor (LHR) in Polycystic Ovarian Syndrome., PMID:34948471

Endogenous, tissue-resident stem/progenitor cells in gonads and bone marrow express FSHR and respond to FSH via FSHR-3., PMID:34717703

Anti-Angiogenic Therapy: Albumin-Binding Proteins Could Mediate Mechanisms Underlying the Accumulation of Small Molecule Receptor Tyrosine Kinase Inhibitors in Normal Tissues with Potential Harmful Effects on Health., PMID:33920299

FSH directly regulates chondrocyte dedifferentiation and cartilage development., PMID:33295881

From cell surface to signalling and back: the life of the mammalian FSH receptor., PMID:33251685

Morphological and Functional Changes in Skin of Adult Male Rats Chronically Treated with Letrozole, a Nonsteroidal Inhibitor of Cytochrome P450 Aromatase., PMID:33177782

FSH for the Treatment of Male Infertility., PMID:32218314

The FSHR Expression in Head and Neck Squamous Cell Cancer. A Pilot Immunohistochemical Study., PMID:31892586

Osteoporosis from an Endocrine Perspective: The Role of Hormonal Changes in the Elderly., PMID:31581477

FSH-metabolic circuitry and menopause., PMID:31454787

Genome-wide association analysis suggests novel loci underlying thyroid antibodies in Hashimoto's thyroiditis., PMID:30926877

Extragonadal FSHR Expression and Function-Is It Real?, PMID:30778333

Follicle-Stimulating Hormone Is an Autocrine Regulator of the Ovarian Cancer Metastatic Niche Through Notch Signaling., PMID:30680340

Follicle-stimulating hormone receptors: A comparison of commercially-available monoclonal and polyclonal antibodies as immunohistochemical markers for cancer research., PMID:30610821

The effects of human menstrual blood stem cells-derived granulosa cells on ovarian follicle formation in a rat model of premature ovarian failure., PMID:30582244

Blocking FSH inhibits hepatic cholesterol biosynthesis and reduces serum cholesterol., PMID:30559440

Engineered DNA Vaccination against Follicle-Stimulating Hormone Receptor Delays Ovarian Cancer Progression in Animal Models., PMID:30554854

Intervention Strategies into Glycoprotein Hormone Receptors for Modulating (Mal-)function, with Special Emphasis on the TSH Receptor., PMID:30366347

Production and validation of a polyclonal serum against bovine FSH receptor., PMID:30220548

Vascular Endothelial FSH Receptor, a Target of Interest for Cancer Therapy., PMID:30113652

Identification of Steroidogenic Components Derived From Gardenia jasminoides Ellis Potentially Useful for Treating Postmenopausal Syndrome., PMID:29899696

Polymorphism FSHR (-29G/A) as a genetic agent together with ESRI (XbaIG/A) in women with poor response to controlled ovarian hyperstimulation., PMID:29526845

Effects of hPMSCs on granulosa cell apoptosis and AMH expression and their role in the restoration of ovary function in premature ovarian failure mice., PMID:29386068

Follicular Stimulating Hormone Accelerates Atherogenesis by Increasing Endothelial VCAM-1 Expression., PMID:29187895

Role of FSHR rs6165 and ESR2 rs4986938 polymorphisms in ovarian stimulation of Iranian women who underwent assisted reproduction treatment., PMID:29036809

Antibody Selection for Cancer Target Validation of FSH-Receptor in Immunohistochemical Settings., PMID:31548530

Datasheet

Document Download

Anti-FSHR Antibody (R3G52).pdf

 

$ 220
Product specifications
50 μg 220 100 μg 350

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Anti-FSHR Antibody (R3G52) [RHD61001]
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