Catalog No.
RHD61001
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
ELISA: 1:10000, FCM: 1:200-1:400
Target
Follitropin receptor, LGR1, Follicle-stimulating hormone receptor, FSHR, FSH-R
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P23945
Applications
ELISA, FCM
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3G52
FSH exacerbates bone loss by promoting osteoclast energy metabolism through the CREB-MDH2-NAD+ axis., PMID:39880362
Immunization with OPN5 increased seasonal degradation of reproductive activity in Magang ganders., PMID:39754930
Active immunization with a novel recombinant GnRH vaccine inhibits reproductive function in male goats., PMID:39708581
Gene-dose-dependent reduction of Fshr expression improves spatial memory deficits in Alzheimer's mice., PMID:39548323
The occurrence of luteinizing hormone-like molecule and its receptor in the blue swimming crab, Portunus pelagicus., PMID:39366546
Antibody fragments targeting the extracellular domain of follicular stimulating hormone receptor for contraception in male dogs and cats., PMID:38875921
Follicle-stimulating hormone receptor expression in advanced atherosclerotic plaques., PMID:38702476
An intracellular VHH targeting the Luteinizing Hormone receptor modulates G protein-dependent signaling and steroidogenesis., PMID:38621656
FSH Is Responsible for Androgen Deprivation Therapy-Associated Atherosclerosis in Mice by Exaggerating Endothelial Inflammation and Monocyte Adhesion., PMID:38205641
Combined Multiplexed Phage Display, High-Throughput Sequencing, and Functional Assays as a Platform for Identifying Modulatory VHHs Targeting the FSHR., PMID:37958944
A single-domain intrabody targeting the follicle-stimulating hormone receptor impacts FSH-induced G protein-dependent signalling., PMID:37923554
Siglec-7 glyco-immune binding mAbs or NK cell engager biologics induce potent antitumor immunity against ovarian cancers., PMID:37910620
FSH and ApoE4 contribute to Alzheimer's disease-like pathogenesis via C/EBPβ/δ-secretase in female mice., PMID:37852961
Impaired Testicular Function without Altering Testosterone Concentration Using an Anti-Follicular-Stimulating Hormone Receptor (Anti-FSHr) Single-Chain Variable Fragment (scFv) in Long-Tailed Macaques (Macaca fascicularis)., PMID:37508065
Inadequate detection of the FSHR complicates future research on extragonadal FSHR localization., PMID:36875462
A mAb against surface-expressed FSHR engineered to engage adaptive immunity for ovarian cancer immunotherapy., PMID:36509287
Effects of dietary organic acids and probiotics on laying performance, egg quality, serum antioxidants and expressions of reproductive genes of laying ducks in the late phase of production., PMID:36240638
Two complementary approaches for efficient isolation of Sertoli cells for transcriptomic analysis., PMID:36158203
TSH receptor antibodies (TRAb) - A potential new biomarker for endometriosis., PMID:36152376
Effects of active immunization against a 13-amino acid receptor-binding epitope of FSHβ on fertility regulation in female mice., PMID:35772190
Follicle stimulating hormone promotes production of renin through its receptor in juxtaglomerular cells of kidney., PMID:35501878
Case report: Birth achieved after effective ovarian stimulation combined with dexamethasone in a patient with resistant ovary syndrome., PMID:35392972
Changes in Expression of Specific mRNA Transcripts after Single- or Re-Irradiation in Mouse Testes., PMID:35052491
Soya saponin improves egg-laying performance and immune function of laying hens., PMID:34986871
Autoimmunity to the Follicle-Stimulating Hormone Receptor (FSHR) and Luteinizing Hormone Receptor (LHR) in Polycystic Ovarian Syndrome., PMID:34948471
Endogenous, tissue-resident stem/progenitor cells in gonads and bone marrow express FSHR and respond to FSH via FSHR-3., PMID:34717703
Anti-Angiogenic Therapy: Albumin-Binding Proteins Could Mediate Mechanisms Underlying the Accumulation of Small Molecule Receptor Tyrosine Kinase Inhibitors in Normal Tissues with Potential Harmful Effects on Health., PMID:33920299
FSH directly regulates chondrocyte dedifferentiation and cartilage development., PMID:33295881
From cell surface to signalling and back: the life of the mammalian FSH receptor., PMID:33251685
Morphological and Functional Changes in Skin of Adult Male Rats Chronically Treated with Letrozole, a Nonsteroidal Inhibitor of Cytochrome P450 Aromatase., PMID:33177782
FSH for the Treatment of Male Infertility., PMID:32218314
The FSHR Expression in Head and Neck Squamous Cell Cancer. A Pilot Immunohistochemical Study., PMID:31892586
Osteoporosis from an Endocrine Perspective: The Role of Hormonal Changes in the Elderly., PMID:31581477
FSH-metabolic circuitry and menopause., PMID:31454787
Genome-wide association analysis suggests novel loci underlying thyroid antibodies in Hashimoto's thyroiditis., PMID:30926877
Extragonadal FSHR Expression and Function-Is It Real?, PMID:30778333
Follicle-Stimulating Hormone Is an Autocrine Regulator of the Ovarian Cancer Metastatic Niche Through Notch Signaling., PMID:30680340
Follicle-stimulating hormone receptors: A comparison of commercially-available monoclonal and polyclonal antibodies as immunohistochemical markers for cancer research., PMID:30610821
The effects of human menstrual blood stem cells-derived granulosa cells on ovarian follicle formation in a rat model of premature ovarian failure., PMID:30582244
Blocking FSH inhibits hepatic cholesterol biosynthesis and reduces serum cholesterol., PMID:30559440
Engineered DNA Vaccination against Follicle-Stimulating Hormone Receptor Delays Ovarian Cancer Progression in Animal Models., PMID:30554854
Intervention Strategies into Glycoprotein Hormone Receptors for Modulating (Mal-)function, with Special Emphasis on the TSH Receptor., PMID:30366347
Production and validation of a polyclonal serum against bovine FSH receptor., PMID:30220548
Vascular Endothelial FSH Receptor, a Target of Interest for Cancer Therapy., PMID:30113652
Identification of Steroidogenic Components Derived From Gardenia jasminoides Ellis Potentially Useful for Treating Postmenopausal Syndrome., PMID:29899696
Polymorphism FSHR (-29G/A) as a genetic agent together with ESRI (XbaIG/A) in women with poor response to controlled ovarian hyperstimulation., PMID:29526845
Effects of hPMSCs on granulosa cell apoptosis and AMH expression and their role in the restoration of ovary function in premature ovarian failure mice., PMID:29386068
Follicular Stimulating Hormone Accelerates Atherogenesis by Increasing Endothelial VCAM-1 Expression., PMID:29187895
Role of FSHR rs6165 and ESR2 rs4986938 polymorphisms in ovarian stimulation of Iranian women who underwent assisted reproduction treatment., PMID:29036809
Antibody Selection for Cancer Target Validation of FSH-Receptor in Immunohistochemical Settings., PMID:31548530