Catalog No.
RHD59603
Species reactivity
Human, Mouse
Host species
Mouse
Isotype
IgG2b
Clonality
Monoclonal
Tested applications
ELISA: 1:10000, FCM: 1:200-1:400, IF: 1:200-1:1000, IHC: 1:200-1:1000, WB: 1:500-1:2000
Target
EIF4B, Eukaryotic translation initiation factor 4B, eIF-4B
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P23588
Applications
ELISA, FCM, IF, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3G40
Elaiophylin targets EIF4B to suppress the growth of esophageal squamous cell carcinoma via the PI3K/AKT signaling pathway., PMID:39694222
Leucine-Rich Alpha-2-Glycoprotein 1 Promotes Metastatic Colorectal Cancer Growth Through Human Epidermal Growth Factor Receptor 3 Signaling., PMID:39393543
Identification of two potential immune-related biomarkers of Graves' disease based on integrated bioinformatics analyses., PMID:35962894
The immunosuppressant tributyltin oxide blocks the mTOR pathway, like rapamycin, albeit by a different mechanism., PMID:24375594
Anthrax lethal toxin inhibits translation of hypoxia-inducible factor 1α and causes decreased tolerance to hypoxic stress., PMID:24366872
Evidence for variation in the optimal translation initiation complex: plant eIF4B, eIF4F, and eIF(iso)4F differentially promote translation of mRNAs., PMID:19493973
Identification and characterization of the expression of the translation initiation factor 4A (eIF4A) from Drosophila melanogaster., PMID:14760701
Intracellular translation initiation factor levels in Saccharomyces cerevisiae and their role in cap-complex function., PMID:12406227
Chaperone hsp27 inhibits translation during heat shock by binding eIF4G and facilitating dissociation of cap-initiation complexes., PMID:10859165
Eukaryotic initiation factor 4B from wheat and Arabidopsis thaliana is a member of a multigene family., PMID:10600500
Mapping the cleavage site in protein synthesis initiation factor eIF-4 gamma of the 2A proteases from human Coxsackievirus and rhinovirus., PMID:8396129
Epidermal growth factor stimulates phosphorylation of eukaryotic initiation factor 4B, independently of protein kinase C., PMID:8388736
Identification of the 80-kDa protein that crosslinks to the cap structure of eukaryotic mRNAs as initiation factor eIF-4B., PMID:3395129
Identification of two messenger RNA cap binding proteins in wheat germ. Evidence that the 28-kDa subunit of eIF-4B and the 26-kDa subunit of eIF-4F are antigenically distinct polypeptides., PMID:2440886
Translational initiation factors from sea urchin eggs and embryos: functional properties are highly conserved., PMID:3767369
Identification and quantitation of levels of protein synthesis initiation factors in crude HeLa cell lysates by two-dimensional polyacrylamide gel electrophoresis., PMID:6853516
Immunochemical characterization of mammalian protein synthesis initiation factors., PMID:6751385
Association of cap-binding protein with eucaryotic initiation factor 3 in initiation factor preparations from uninfected and poliovirus-infected HeLa cells., PMID:6283140
For research use only. Not for human or drug use.
