Catalog No.
RHD48901
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
IF: 1:200-1:1000
Target
CMP, MATN1, Cartilage matrix protein, Matrilin-1, CRTM
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P21941
Applications
IF
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3G02
Hmgb1 can facilitate activation of the matrilin-1 gene promoter by Sox9 and L-Sox5/Sox6 in early steps of chondrogenesis., PMID:23860260
Enhanced COMP catabolism detected in serum of patients with arthritis and animal disease models through a novel capture ELISA., PMID:22595227
Tricomponent immunopotentiating system as a novel molecular design strategy for malaria vaccine development., PMID:21807905
Detection of cartilage oligomeric matrix protein using a quartz crystal microbalance., PMID:22163547
Cartilage oligomeric matrix protein in canine spinal cord appears in the cerebrospinal fluid associated with intervertebral disc herniation., PMID:20042950
Cartilage oligomeric matrix protein promotes cell attachment via two independent mechanisms involving CD47 and alphaVbeta3 integrin., PMID:20033473
Combined role of type IX collagen and cartilage oligomeric matrix protein in cartilage matrix assembly: cartilage oligomeric matrix protein counteracts type IX collagen-induced limitation of cartilage collagen fibril growth in mouse chondrocyte cultures., PMID:19950300
Proteolytic processing causes extensive heterogeneity of tissue matrilin forms., PMID:19531486
Sandwich ELISA system for cartilage oligomeric matrix protein in equine synovial fluid and serum., PMID:19301580
Cartilage oligomeric matrix protein deficiency promotes early onset and the chronic development of collagen-induced arthritis., PMID:19014566
Cartilage oligomeric matrix protein induction of chronic arthritis in mice., PMID:18576344
The cartilage matrix protein subdomain of type VII collagen is pathogenic for epidermolysis bullosa acquisita., PMID:17525268
Cartilage oligomeric matrix protein associates with granulin-epithelin precursor (GEP) and potentiates GEP-stimulated chondrocyte proliferation., PMID:17307734
Pericellular matrilins regulate activation of chondrocytes by cyclic load-induced matrix deformation., PMID:17129169
Altered integration of matrilin-3 into cartilage extracellular matrix in the absence of collagen IX., PMID:16287859
Multivalent recombinant proteins for probing functions of leucocyte surface proteins such as the CD200 receptor., PMID:15946251
Analysis of cartilage oligomeric matrix protein (COMP) degradation and synthesis in equine joint disease., PMID:15651731
Zebrafish (Danio rerio) matrilins: shared and divergent characteristics with their mammalian counterparts., PMID:15588228
Critical role of the major histocompatibility complex and IL-10 in matrilin-1-induced relapsing polychondritis in mice., PMID:15380048
Relapsing polychondritis, induced in mice with matrilin 1, is an antibody- and complement-dependent disease., PMID:14982849
Mutation (D472Y) in the type 3 repeat domain of cartilage oligomeric matrix protein affects its early vesicle trafficking in endoplasmic reticulum and induces apoptosis., PMID:12819015
Peptabodies as tools to test ligands isolated from phage-displayed peptide libraries., PMID:12738366
Immunohistochemical study of matrilin-1 in arthritic articular cartilage of the mandibular condyle., PMID:12653864
The occurrence of autoantibodies to matrilin 1 reflects a tissue-specific response to cartilage of the respiratory tract in patients with relapsing polychondritis., PMID:11665983
Molecular properties of matrilin-3 isolated from human growth cartilage., PMID:11370843
Autoreactivity against matrilin-1 in a patient with relapsing polychondritis., PMID:10765942
Distribution of cartilage molecules in the developing mouse joint., PMID:10601736
IL-1 alpha beta blockade prevents cartilage and bone destruction in murine type II collagen-induced arthritis, whereas TNF-alpha blockade only ameliorates joint inflammation., PMID:10528210
Enhancement of cell adhesion and spreading by a cartilage-specific noncollagenous protein, cartilage matrix protein (CMP/Matrilin-1), via integrin alpha1beta1., PMID:10196235
Characterization of monoclonal antibodies recognizing different fragments of cartilage oligomeric matrix protein in human body fluids., PMID:9143347
Cartilage matrix protein: expression patterns in chicken, mouse, and human., PMID:8702140
Morphologic and molecular changes during the post-natal development of the rabbit vitreous., PMID:1397132
Cartilage matrix glycoprotein is present in serum in experimental canine osteoarthritis., PMID:2808699