Catalog No.
RHD47001
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
IHC: 1:200-1:1000, WB: 1:500-1:2000
Target
Tyrosine-protein kinase receptor EPH, EPHT1, Erythropoietin-producing hepatoma receptor, hEpha1, EPH, EPHA1, Ephrin type-A receptor 1, EPH tyrosine kinase 1, EPH tyrosine kinase, EPHT
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P21709
Applications
IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3F91
Prostate cancer cell-platelet bidirectional signaling promotes calcium mobilization, invasion and apoptotic resistance via distinct receptor-ligand pairs., PMID:36806315
Systematic Engineering of Optimized Autonomous Heavy-Chain Variable Domains., PMID:34508727
A Path Toward Precision Medicine for Neuroinflammatory Mechanisms in Alzheimer's Disease., PMID:32296418
Inhibition of EphA/Ephrin-A signaling using genetic and pharmacologic approaches improves recovery following traumatic brain injury in mice., PMID:31319723
Serum biomarker panels for the diagnosis of gastric cancer., PMID:30873760
A potential role for Eph receptor signalling during migration of corneal endothelial cells., PMID:29476773
Glycoengineering of EphA4 Fc leads to a unique, long-acting and broad spectrum, Eph receptor therapeutic antagonist., PMID:28747680
EphA2 receptor activation with ephrin-A1 ligand restores cetuximab efficacy in NRAS-mutant colorectal cancer cells., PMID:28560458
Altered S-nitrosothiol homeostasis provides a survival advantage to breast cancer cells in HER2 tumors and reduces their sensitivity to trastuzumab., PMID:26854735
Expression of the EphA1 protein is associated with Fuhrman nuclear grade in clear cell renal cell carcinomas., PMID:26261568
ADAM12-cleaved ephrin-A1 contributes to lung metastasis., PMID:23686306
Evaluation of Eph receptor and ephrin expression within the human cornea and limbus., PMID:23247085
The protection of acetylcholinesterase inhibitor on β-amyloid-induced the injury of neurite outgrowth via regulating axon guidance related genes expression in neuronal cells., PMID:23119107
Targeting of EPH receptor tyrosine kinases for anticancer therapy., PMID:22471709
Alzheimer's Disease: APP, Gamma Secretase, APOE, CLU, CR1, PICALM, ABCA7, BIN1, CD2AP, CD33, EPHA1, and MS4A2, and Their Relationships with Herpes Simplex, C. Pneumoniae, Other Suspect Pathogens, and the Immune System., PMID:22254144
Complex expression patterns of Eph receptor tyrosine kinases and their ephrin ligands in colorectal carcinogenesis., PMID:21852108
EphrinA/EphA signal facilitates insulin-like growth factor-I-induced myogenic differentiation through suppression of the Ras/extracellular signal-regulated kinase 1/2 cascade in myoblast cell lines., PMID:21795402
Sesamin induces autophagy in colon cancer cells by reducing tyrosine phosphorylation of EphA1 and EphB2., PMID:21503576
Intramyocardial administration of chimeric ephrinA1-Fc promotes tissue salvage following myocardial infarction in mice., PMID:21282286
[Neuronal identity and axonal projection of olfactory sensory neurons]., PMID:17552283
Comparison of EphA receptor tyrosine kinases and ephrinA ligand expression to EphB-ephrinB in vascularized corneas., PMID:17525654
Differential gene expression in non-malignant tumour microenvironment is associated with outcome in follicular lymphoma patients treated with rituximab and CHOP., PMID:16925574
Giant cell tumors of the bone: molecular profiling and expression analysis of Ephrin A1 receptor, Claudin 7, CD52, FGFR3 and AMFR., PMID:16325507
EphA receptor tyrosine kinases interact with co-expressed ephrin-A ligands in cis., PMID:15154674
Identification of tyrosine kinases overexpressed in head and neck cancer., PMID:15023838
Identification of NPM-ALK interacting proteins by tandem mass spectrometry., PMID:14968112
Ephrin-A1 suppresses Th2 cell activation and provides a regulatory link to lung epithelial cells., PMID:14707054
EphA4 provides repulsive signals to developing cochlear ganglion neurites mediated through ephrin-B2 and -B3., PMID:12761826
Topographic-specific axon branching controlled by ephrin-As is the critical event in retinotectal map development., PMID:11606643
Ephrin-A5 modulates cell adhesion and morphology in an integrin-dependent manner., PMID:11032807
PSK, a novel STE20-like kinase derived from prostatic carcinoma that activates the c-Jun N-terminal kinase mitogen-activated protein kinase pathway and regulates actin cytoskeletal organization., PMID:10660600
For research use only. Not for human or drug use.
