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Anti-CD247/CD3Z Antibody (R3F80)

Catalog #:   RHD44104 Specific References (21) DATASHEET
Host species: Mouse
Isotype: IgG1
Applications: FCM, IF, IHC
Accession: P20963
Overview

Catalog No.

RHD44104

Species reactivity

Human

Host species

Mouse

Isotype

IgG1

Clonality

Monoclonal

Tested applications

FCM: 1:200-1:400, IF: 1:200-1:1000, IHC: 1:200-1:1000

Target

CD3Z, CD247, TCRZ, T-cell receptor T3 zeta chain, T3Z, T-cell surface glycoprotein CD3 zeta chain

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P20963

Applications

FCM, IF, IHC

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R3F80

Data Image
  • Flow Cytometry
    Flow cytometric analysis of Jurkat cells using anti-CD247 mAb (green) and negative control (purple).
  • Immunofluorescence
    Figure3: Immunofluorescence analysis of K562 cells using anti-CD247 mAb (green). Blue: DRAQ5 fluorescent DNA dye.
  • Immunohistochemical
    Immunohistochemical analysis of paraffin-embedded human Thymus tissues using anti-CD247 mouse mAb
References

Risk of celiac disease autoimmunity is modified by interactions between CD247 and environmental exposures., PMID:39462122

Effects of immunorelated gene polymorphisms on trastuzumab targeting breast cancer cell in vitro., PMID:39392082

Nonsense CD247 mutations show dominant-negative features in T-cell receptor expression and function., PMID:38992472

Identification of a Fully Human Antibody VH Domain Targeting Anaplastic Lymphoma Kinase (ALK) with Applications in ALK-Positive Solid Tumor Immunotherapy., PMID:38804307

Biomarkers in the Pathogenesis, Diagnosis, and Treatment of Systemic Sclerosis., PMID:37868834

Advances in the study of CD47-based bispecific antibody in cancer immunotherapy., PMID:35575882

Human Cytomegalovirus Infection Promotes Expansion of a Functionally Superior Cytoplasmic CD3+ NK Cell Subset with a Bcl11b-Regulated T Cell Signature., PMID:34625521

CAR T-cell therapy for multiple myeloma: state of the art and prospects., PMID:34048683

The Role of CD247 Polymorphisms in Bulgarian Patients with Systemic Lupus Erythematosus., PMID:30064597

Effects of immuno-related gene polymorphisms on a bispecific antibody targeting colorectal cancer cell., PMID:29790821

Clinical Significance of Circulating CD33+CD11b+HLA-DR- Myeloid Cells in Patients with Stage IV Melanoma Treated with Ipilimumab., PMID:27178742

TCR-CD3ζ gene polymorphisms and expression profile in rheumatoid arthritis., PMID:27118209

Effect of induction therapy on the expression of molecular markers associated with rejection and tolerance., PMID:26286066

Expression pattern of T-helper 17 cell signaling pathway and mucosal inflammation in celiac disease., PMID:24325470

Down regulation of T cell receptor expression in COPD pulmonary CD8 cells., PMID:23977094

IRF5 polymorphism predicts prognosis in patients with systemic sclerosis., PMID:22440820

Association of CD247 with systemic lupus erythematosus in Asian populations., PMID:22004975

Using gene co-expression network analysis to predict biomarkers for chronic lymphocytic leukemia., PMID:21044363

Interleukin-21 can efficiently restore impaired antibody-dependent cell-mediated cytotoxicity in patients with oesophageal squamous cell carcinoma., PMID:20029417

Elements related to heterogeneity of antibody-dependent cell cytotoxicity in patients under trastuzumab therapy for primary operable breast cancer overexpressing Her2., PMID:18089830

Profiling lymphocyte subpopulations in peripheral blood under efalizumab treatment of psoriasis by multi epitope ligand cartography (MELC) robot microscopy., PMID:17229602

Datasheet
$ 220
Product specifications
50 μg 220 100 μg 350

Contact Information

Order: order@antibodysystem.com

Mail: support@antibodysystem.com

Distributor list

For research use only. Not for human or drug use.

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Anti-CD247/CD3Z Antibody (R3F80) [RHD44104]
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