Catalog No.
RHD39001
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
ELISA: 1:10000, FCM: 1:200-1:400
Target
Ras-related protein Rab-3A, RAB3A
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P20336
Applications
ELISA, FCM
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3F67
α-Synuclein is required for sperm exocytosis at a post-fusion stage., PMID:37287458
Temperature regulates Rab3a and mast cell-derived exosomal FcεRI to inhibit mast cell activation., PMID:37069491
The Olfactomedin-4-Defined Human Neutrophil Subsets Differ in Proteomic Profile in Healthy Individuals and Patients with Septic Shock., PMID:36450268
A 7-year-old boy with central diabetes insipidus presenting with thickened pituitary stalk and anti-rabphilin-3A antibody positivity., PMID:35119230
Synaptic localization of C9orf72 regulates post-synaptic glutamate receptor 1 levels., PMID:31651360
Grab recruitment by Rab27A-Rabphilin3a triggers Rab3A activation in human sperm exocytosis., PMID:30599141
SNARE Complex-Associated Proteins in the Lateral Amygdala of Macaca mulatta Following Long-Term Ethanol Drinking., PMID:29944190
Development of phospho-specific Rab protein antibodies to monitor in vivo activity of the LRRK2 Parkinson's disease kinase., PMID:29127256
Gene cloning, expression and polyclonal antibody preparation of Rab3A for protein interaction analysis., PMID:27795879
Rab3A, a possible marker of cortical granules, participates in cortical granule exocytosis in mouse eggs., PMID:27423421
Rab3A, Rab27A, and Rab35 regulate different events during mouse oocyte meiotic maturation and activation., PMID:26791531
GTP-bound Rab3A exhibits consecutive positive and negative roles during human sperm dense-core granule exocytosis., PMID:25053757
Regulation of acrosome reaction by Liprin α3, LAR and its ligands in mouse spermatozoa., PMID:24327330
The GTPase Rab37 Participates in the Control of Insulin Exocytosis., PMID:23826383
α-Synuclein membrane association is regulated by the Rab3a recycling machinery and presynaptic activity., PMID:23344955
Rab27 and Rab3 sequentially regulate human sperm dense-core granule exocytosis., PMID:22753498
RIM, Munc13, and Rab3A interplay in acrosomal exocytosis., PMID:22248876
Identification and characterisation of novel Mss4-binding Rab GTPases., PMID:21194374
Rab3a interacting molecule (RIM) and the tethering of pre-synaptic transmitter release site-associated CaV2.2 calcium channels., PMID:19878533
IA-2 modulates dopamine secretion in PC12 cells., PMID:19799965
PTP1B dephosphorylates N-ethylmaleimide-sensitive factor and elicits SNARE complex disassembly during human sperm exocytosis., PMID:19208619
The role of RIM1alpha in BDNF-enhanced glutamate release., PMID:18499195
Synaptic vesicle protein 2B is expressed in podocyte, and its expression is altered in proteinuric glomeruli., PMID:16943307
Impact of del32-71-GH (exon 3 skipped GH) on intracellular GH distribution, secretion and cell viability: a quantitative confocal microscopy analysis., PMID:16491012
Assay of the Rab-binding specificity of rabphilin and Noc2: target molecules for Rab27., PMID:16473612
Analysis of the role of Rab27 effector Slp4-a/Granuphilin-a in dense-core vesicle exocytosis., PMID:16473610
Long splice variant N type calcium channels are clustered at presynaptic transmitter release sites without modular adaptor proteins., PMID:16473471
Calcium-induced acrosomal exocytosis requires cAMP acting through a protein kinase A-independent, Epac-mediated pathway., PMID:16407249
Dynamics of SNARE assembly and disassembly during sperm acrosomal exocytosis., PMID:16131227
alpha-SNAP and NSF are required in a priming step during the human sperm acrosome reaction., PMID:15542541
Developmental expression of the Ca2+-binding proteins calretinin and parvalbumin at the calyx of Held of rats and mice., PMID:15355314
Synapsin is a novel Rab3 effector protein on small synaptic vesicles. I. Identification and characterization of the synapsin I-Rab3 interactions in vitro and in intact nerve terminals., PMID:15265865
Abnormal alpha-synuclein interactions with rab3a and rabphilin in diffuse Lewy body disease., PMID:15207266
Requirement of protein tyrosine kinase and phosphatase activities for human sperm exocytosis., PMID:14732401
Vesicular localization and activity-dependent trafficking of presynaptic choline transporters., PMID:14585997
The expression pattern and assembly profile of synaptic membrane proteins in ribbon synapses of the developing mouse retina., PMID:12596036
Phosphorylation of 46-kDa protein of synaptic vesicle membranes is stimulated by GTP and Ca2+/calmodulin., PMID:12526085
Nerve growth factor-dependent sorting of synaptotagmin IV protein to mature dense-core vesicles that undergo calcium-dependent exocytosis in PC12 cells., PMID:12446703
Identification of SNARE and cell trafficking regulatory proteins in the salivary glands of the lone star tick, Amblyomma americanum (L.)., PMID:12429123
SNARE complex assembly is required for human sperm acrosome reaction., PMID:11884041
Rabconnectin-3, a novel protein that binds both GDP/GTP exchange protein and GTPase-activating protein for Rab3 small G protein family., PMID:11809763
Characterization of rabphilin phosphorylation using phospho-specific antibodies., PMID:11640918
Physiological modulation of rabphilin phosphorylation., PMID:11466418
Developmental regulation and specific brain distribution of phosphorabphilin., PMID:11466417
Carboxyl-methylation of Rab3D in the rat pancreatic acinar tumor cell line AR42J., PMID:11453651
Transient increase in rab 3A and synaptobrevin immunoreactivity after mild hypoxia in neonatal rats., PMID:11440197
Synaptotagmin VI participates in the acrosome reaction of human spermatozoa., PMID:11437455
Differential expression of Rab3 isoforms in high- and low-secreting mast cell lines., PMID:11370744
Rab3A and Rab3D control the total granule number and the fraction of granules docked at the plasma membrane in PC12 cells., PMID:11208087
Reduction of the synaptic protein rab3a in the thalamus and connecting brain regions in post-mortem schizophrenic brains., PMID:11041284
For research use only. Not for human or drug use.
