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Anti-PPM1A Antibody (R3F58)

Catalog #:   RHE15802 Specific References (14) DATASHEET
Host species: Mouse
Isotype: IgG1
Applications: ELISA, FCM, WB
Accession: P35813
Overview

Catalog No.

RHE15802

Species reactivity

Human, Monkey

Host species

Mouse

Isotype

IgG1

Clonality

Monoclonal

Tested applications

ELISA: 1:10000, FCM: 1:200-1:400, WB: 1:500-1:2000

Target

Protein phosphatase 2C isoform alpha, PPPM1A, Protein phosphatase 1A, Protein phosphatase IA, PP2C-alpha, PPM1A

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P35813

Applications

ELISA, FCM, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R3F58

Data Image
  • Flow Cytometry
    Flow cytometric analysis of HeLa cells using PPM1A mouse mAb (green) and negative control (red).
  • Western blot
    Western blot analysis using PPM1A mouse mAb against Jurkat (1), Jurkat (2), A431 (3), HeLa (4), HEK293 (5), Raji (6), MCF-7 (7), and COS7 (8) cell lysate.
References

Anti-protein phosphatase magnesium-dependent 1A-IgM levels in patients with active ankylosing spondylitis: a potential biomarker., PMID:39272166

Negative regulators of TGF-β1 signaling in renal fibrosis; pathological mechanisms and novel therapeutic opportunities., PMID:33480423

Autoantibodies against Protein Phosphatase Magnesium-Dependent 1A as a Biomarker for Predicting Radiographic Progression in Ankylosing Spondylitis Treated with Anti-Tumor Necrosis Factor Agents., PMID:33297507

MiR-1165-3p Suppresses Th2 Differentiation via Targeting IL-13 and PPM1A in a Mouse Model of Allergic Airway Inflammation., PMID:32638565

Autoantibodies in Spondyloarthritis, Focusing on Anti-CD74 Antibodies., PMID:30723468

Hepatitis C virus NS3 protein enhances hepatocellular carcinoma cell invasion by promoting PPM1A ubiquitination and degradation., PMID:28283039

Notch signaling indirectly promotes chondrocyte hypertrophy via regulation of BMP signaling and cell cycle arrest., PMID:27146698

Protein Phosphatase 2C of Toxoplasma Gondii Interacts with Human SSRP1 and Negatively Regulates Cell Apoptosis., PMID:25374021

Role of protein phosphatase magnesium-dependent 1A and anti-protein phosphatase magnesium-dependent 1A autoantibodies in ankylosing spondylitis., PMID:24980965

Ppm1E is an in cellulo AMP-activated protein kinase phosphatase., PMID:20801214

Toxoplasma gondii targets a protein phosphatase 2C to the nuclei of infected host cells., PMID:17085638

Protein phosphatase-2C alpha as a positive regulator of insulin sensitivity through direct activation of phosphatidylinositol 3-kinase in 3T3-L1 adipocytes., PMID:15016818

Cell cycle regulation and p53 activation by protein phosphatase 2C alpha., PMID:12514180

Protein phosphatase 2C inactivates F-actin binding of human platelet moesin., PMID:10480873

Datasheet

Document Download

Anti-PPM1A Antibody (R3F58).pdf

 

$ 220
Product specifications
50 μg 220 100 μg 350

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Anti-PPM1A Antibody (R3F58) [RHE15802]
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