Catalog No.
RHD35901
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a
Clonality
Monoclonal
Tested applications
ELISA: 1:10000, FCM: 1:200-1:400, IF: 1:200-1:1000, IHC: 1:200-1:1000, WB: 1:500-1:2000
Target
Nuclear factor NF-kappa-B p105 subunit, EBP-1, NFKB1, Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, DNA-binding factor KBF1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P19838
Applications
ELISA, FCM, IF, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3F45
Single-cell transcriptomic profiling reveals dysregulation of B-cell subset function in patients with chronic hepatitis B., PMID:40489024
Macrophage activation determines muscle wasting in pancreatic cancer., PMID:40442475
A novel NFKB1 agonist remodels tumor microenvironment and activates dendritic cells to promote anti-tumor immunity in colorectal cancer., PMID:40394677
Common variable immunodeficiency due to a novel variant in NFKB1 with a neonatal presentation of parechovirus meningitis and sepsis-like illness., PMID:40342112
The Burden of Non-Infectious Organ-Specific Immunopathology in Pediatric Common Variable Immunodeficiency., PMID:40141295
NF-ΚB Activation as a Key Driver in Chronic Lymphocytic Leukemia Evolution to Richter's Syndrome: Unraveling the Influence of Immune Microenvironment Dynamics., PMID:39596634
Immunoliposome-based targeted delivery of the CRISPR/Cas9gRNA-IL30 complex inhibits prostate cancer and prolongs survival., PMID:39232121
Formononetin inhibits IgE by huPlasma/PBMCs and mast cells/basophil activation via JAK/STAT/PI3-Akt pathways., PMID:39221239
Clinical, Immunological, and Genetic Features in Patients with NFKB1 and NFKB2 Mutations: a Systematic Review., PMID:38990428
Coexistence of systemic sclerosis and cryopyrin-associated periodic syndrome., PMID:38940218
Exploration of the Shared Gene Signatures and Molecular Mechanisms between Chronic Bronchitis and Antineutrophil Cytoplasmic Antibody-associated Glomerulonephritis: Evidence from Transcriptome Data., PMID:38847168
Pre-vaccination transcriptomic profiles of immune responders to the MUC1 peptide vaccine for colon cancer prevention., PMID:38766010
The Scope and Impact of Viral Infections in Common Variable Immunodeficiency (CVID) and CVID-like Disorders: A Literature Review., PMID:38541942
Exploring personalized treatment for cardiac graft rejection based on a four-archetype analysis model and bioinformatics analysis., PMID:38499711
A common NFKB1 variant detected through antibody analysis in UK Biobank predicts risk of infection and allergy., PMID:38232728
TNF-α induced NF-κB mediated LYRM7 expression modulates the tumor growth and metastatic ability in breast cancer., PMID:38104742
The role of SARS-CoV-2-mediated NF-κB activation in COVID-19 patients., PMID:37872376
NF-κB and STAT3 activation in CD4 T cells in pediatric MOG antibody-associated disease., PMID:37770354
Small-Extracellular-Vesicle-Derived miRNA Profile Identifies miR-483-3p and miR-326 as Regulators in the Pathogenesis of Antiphospholipid Syndrome (APS)., PMID:37511365
Corrigendum: Vulnerability to meningococcal disease in immunodeficiency due to a novel pathogenic missense variant in NFKB1., PMID:37234149
Paradoxical activation of chronic lymphocytic leukemia cells by ruxolitinib in vitro and in vivo., PMID:37114129
A Genetic Risk Score Distinguishes Different Types of Autoantibody-Mediated Membranous Nephropathy., PMID:37090184
Comprehensive proteomics and platform validation of urinary biomarkers for bladder cancer diagnosis and staging., PMID:37016361
Longitudinal transcriptional analysis of peripheral blood leukocytes in COVID-19 convalescent donors., PMID:36510222
1270 nm near-infrared light as a novel vaccine adjuvant acts on mitochondrial photoreception in intradermal vaccines., PMID:36439134
PAUF Induces Migration of Human Pancreatic Cancer Cells Exclusively via the TLR4/MyD88/NF-κB Signaling Pathway., PMID:36232715
Effect of Saccharomyces cerevisiae fermentation product on oxidative status, inflammation, and immune response in transition dairy cattle., PMID:36153156
Autoimmune Cytopenias in Common Variable Immunodeficiency Are a Diagnostic and Therapeutic Conundrum: An Update., PMID:35795667
Common Variable Immunodeficiency and Neurodevelopmental Delay Due to a 13Mb Deletion on Chromosome 4 Including the NFKB1 Gene: A Case Report., PMID:35784294
Identifying predictive signalling networks for Vedolizumab response in ulcerative colitis., PMID:35543875
Vulnerability to Meningococcal Disease in Immunodeficiency Due to a Novel Pathogenic Missense Variant in NFKB1., PMID:35003082
Establishing the Molecular Diagnoses in a Cohort of 291 Patients With Predominantly Antibody Deficiency by Targeted Next-Generation Sequencing: Experience From a Monocentric Study., PMID:34975878
Functional screen of inflammatory bowel disease genes reveals key epithelial functions., PMID:34758847
Assessment of genetic polymorphisms within nuclear factor-κB signaling pathway genes in rheumatoid arthritis: Evidence for replication and genetic interaction., PMID:34464884
Immunogenicity of Pfizer-BioNTech COVID-19 vaccine in patients with inborn errors of immunity., PMID:34087242
A Pathogenic Missense Variant in NFKB1 Causes Common Variable Immunodeficiency Due to Detrimental Protein Damage., PMID:33995346
Pseudocell Tracer-A method for inferring dynamic trajectories using scRNAseq and its application to B cells undergoing immunoglobulin class switch recombination., PMID:33939691
Management of Myeloma Bone Lesions., PMID:33806209
Inhibition of TNFR1 Attenuates LPS Induced Apoptosis and Inflammation in Human Nucleus Pulposus Cells by Regulating the NF-KB and MAPK Signalling Pathway., PMID:33713325
Recurrent necrotizing cellulitis, multi-organ autoimmune disease and humoral immunodeficiency due to a novel NFKB1 frameshift mutation., PMID:33486103
BAFF, involved in B cell activation through the NF-κB pathway, is related to disease activity and bone destruction in rheumatoid arthritis., PMID:33483588
Deep phenotyping of synovial molecular signatures by integrative systems analysis in rheumatoid arthritis., PMID:33230538
VISTA Re-programs Macrophage Biology Through the Combined Regulation of Tolerance and Anti-inflammatory Pathways., PMID:33178206
Transcriptome Profiling of Human Monocyte-Derived Macrophages Upon CCL2 Neutralization Reveals an Association Between Activation of Innate Immune Pathways and Restriction of HIV-1 Gene Expression., PMID:33072075
Combined immunodeficiency caused by a novel homozygous NFKB1 mutation., PMID:32980423
Hyaluronan oligosaccharides modulate inflammatory response, NIS and thyreoglobulin expression in human thyrocytes., PMID:32976824
Inflammation: A bridge between diabetes and COVID-19, and possible management with sitagliptin., PMID:32721805
Tacrolimus Prevents TWEAK-Induced PLA2R Expression in Cultured Human Podocytes., PMID:32664235
Fisetin alleviates sepsis-induced multiple organ dysfunction in mice via inhibiting p38 MAPK/MK2 signaling., PMID:32661350
Clinical Management and Therapeutic Strategies for the Thyroid-Associated Ophthalmopathy: Current and Future Perspectives., PMID:32567373
For research use only. Not for human or drug use.
