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Anti-NFKB1 Antibody (R3F44)

Catalog #:   RHD35902 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG2a
Applications: ELISA, FCM, IHC, WB
Accession: P19838
Overview

Catalog No.

RHD35902

Species reactivity

Human

Host species

Mouse

Isotype

IgG2a

Clonality

Monoclonal

Tested applications

ELISA: 1:10000, FCM: 1:200-1:400, IHC: 1:200-1:1000, WB: 1:500-1:2000

Target

Nuclear factor NF-kappa-B p105 subunit, EBP-1, NFKB1, Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, DNA-binding factor KBF1

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P19838

Applications

ELISA, FCM, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R3F44

Data Image
  • Flow Cytometry
    Flow cytometric analysis of MCF-7 cells using NFKB1 mouse mAb (green) and negative control (purple).
  • Immunohistochemical
    Immunohistochemical analysis of paraffin-embedded human prostate tissues (left) and bladder cancer tissues (right) using NFKB1 mouse mAb with DAB staining.
  • Western blot
    Western blot analysis using NFKB1 mouse mAb against K562 (1), Jurkat (2), A431 (3), Hela (4), THP-1 (5) and MCF-7 (6) cell lysate.
References

Single-cell transcriptomic profiling reveals dysregulation of B-cell subset function in patients with chronic hepatitis B., PMID:40489024

Macrophage activation determines muscle wasting in pancreatic cancer., PMID:40442475

A novel NFKB1 agonist remodels tumor microenvironment and activates dendritic cells to promote anti-tumor immunity in colorectal cancer., PMID:40394677

Common variable immunodeficiency due to a novel variant in NFKB1 with a neonatal presentation of parechovirus meningitis and sepsis-like illness., PMID:40342112

The Burden of Non-Infectious Organ-Specific Immunopathology in Pediatric Common Variable Immunodeficiency., PMID:40141295

NF-ΚB Activation as a Key Driver in Chronic Lymphocytic Leukemia Evolution to Richter's Syndrome: Unraveling the Influence of Immune Microenvironment Dynamics., PMID:39596634

Immunoliposome-based targeted delivery of the CRISPR/Cas9gRNA-IL30 complex inhibits prostate cancer and prolongs survival., PMID:39232121

Formononetin inhibits IgE by huPlasma/PBMCs and mast cells/basophil activation via JAK/STAT/PI3-Akt pathways., PMID:39221239

Clinical, Immunological, and Genetic Features in Patients with NFKB1 and NFKB2 Mutations: a Systematic Review., PMID:38990428

Coexistence of systemic sclerosis and cryopyrin-associated periodic syndrome., PMID:38940218

Exploration of the Shared Gene Signatures and Molecular Mechanisms between Chronic Bronchitis and Antineutrophil Cytoplasmic Antibody-associated Glomerulonephritis: Evidence from Transcriptome Data., PMID:38847168

Pre-vaccination transcriptomic profiles of immune responders to the MUC1 peptide vaccine for colon cancer prevention., PMID:38766010

The Scope and Impact of Viral Infections in Common Variable Immunodeficiency (CVID) and CVID-like Disorders: A Literature Review., PMID:38541942

Exploring personalized treatment for cardiac graft rejection based on a four-archetype analysis model and bioinformatics analysis., PMID:38499711

A common NFKB1 variant detected through antibody analysis in UK Biobank predicts risk of infection and allergy., PMID:38232728

TNF-α induced NF-κB mediated LYRM7 expression modulates the tumor growth and metastatic ability in breast cancer., PMID:38104742

The role of SARS-CoV-2-mediated NF-κB activation in COVID-19 patients., PMID:37872376

NF-κB and STAT3 activation in CD4 T cells in pediatric MOG antibody-associated disease., PMID:37770354

Small-Extracellular-Vesicle-Derived miRNA Profile Identifies miR-483-3p and miR-326 as Regulators in the Pathogenesis of Antiphospholipid Syndrome (APS)., PMID:37511365

Corrigendum: Vulnerability to meningococcal disease in immunodeficiency due to a novel pathogenic missense variant in NFKB1., PMID:37234149

Paradoxical activation of chronic lymphocytic leukemia cells by ruxolitinib in vitro and in vivo., PMID:37114129

A Genetic Risk Score Distinguishes Different Types of Autoantibody-Mediated Membranous Nephropathy., PMID:37090184

Comprehensive proteomics and platform validation of urinary biomarkers for bladder cancer diagnosis and staging., PMID:37016361

Longitudinal transcriptional analysis of peripheral blood leukocytes in COVID-19 convalescent donors., PMID:36510222

1270 nm near-infrared light as a novel vaccine adjuvant acts on mitochondrial photoreception in intradermal vaccines., PMID:36439134

PAUF Induces Migration of Human Pancreatic Cancer Cells Exclusively via the TLR4/MyD88/NF-κB Signaling Pathway., PMID:36232715

Effect of Saccharomyces cerevisiae fermentation product on oxidative status, inflammation, and immune response in transition dairy cattle., PMID:36153156

Autoimmune Cytopenias in Common Variable Immunodeficiency Are a Diagnostic and Therapeutic Conundrum: An Update., PMID:35795667

Common Variable Immunodeficiency and Neurodevelopmental Delay Due to a 13Mb Deletion on Chromosome 4 Including the NFKB1 Gene: A Case Report., PMID:35784294

Identifying predictive signalling networks for Vedolizumab response in ulcerative colitis., PMID:35543875

Vulnerability to Meningococcal Disease in Immunodeficiency Due to a Novel Pathogenic Missense Variant in NFKB1., PMID:35003082

Establishing the Molecular Diagnoses in a Cohort of 291 Patients With Predominantly Antibody Deficiency by Targeted Next-Generation Sequencing: Experience From a Monocentric Study., PMID:34975878

Functional screen of inflammatory bowel disease genes reveals key epithelial functions., PMID:34758847

Assessment of genetic polymorphisms within nuclear factor-κB signaling pathway genes in rheumatoid arthritis: Evidence for replication and genetic interaction., PMID:34464884

Immunogenicity of Pfizer-BioNTech COVID-19 vaccine in patients with inborn errors of immunity., PMID:34087242

A Pathogenic Missense Variant in NFKB1 Causes Common Variable Immunodeficiency Due to Detrimental Protein Damage., PMID:33995346

Pseudocell Tracer-A method for inferring dynamic trajectories using scRNAseq and its application to B cells undergoing immunoglobulin class switch recombination., PMID:33939691

Management of Myeloma Bone Lesions., PMID:33806209

Inhibition of TNFR1 Attenuates LPS Induced Apoptosis and Inflammation in Human Nucleus Pulposus Cells by Regulating the NF-KB and MAPK Signalling Pathway., PMID:33713325

Recurrent necrotizing cellulitis, multi-organ autoimmune disease and humoral immunodeficiency due to a novel NFKB1 frameshift mutation., PMID:33486103

BAFF, involved in B cell activation through the NF-κB pathway, is related to disease activity and bone destruction in rheumatoid arthritis., PMID:33483588

Deep phenotyping of synovial molecular signatures by integrative systems analysis in rheumatoid arthritis., PMID:33230538

VISTA Re-programs Macrophage Biology Through the Combined Regulation of Tolerance and Anti-inflammatory Pathways., PMID:33178206

Transcriptome Profiling of Human Monocyte-Derived Macrophages Upon CCL2 Neutralization Reveals an Association Between Activation of Innate Immune Pathways and Restriction of HIV-1 Gene Expression., PMID:33072075

Combined immunodeficiency caused by a novel homozygous NFKB1 mutation., PMID:32980423

Hyaluronan oligosaccharides modulate inflammatory response, NIS and thyreoglobulin expression in human thyrocytes., PMID:32976824

Inflammation: A bridge between diabetes and COVID-19, and possible management with sitagliptin., PMID:32721805

Tacrolimus Prevents TWEAK-Induced PLA2R Expression in Cultured Human Podocytes., PMID:32664235

Fisetin alleviates sepsis-induced multiple organ dysfunction in mice via inhibiting p38 MAPK/MK2 signaling., PMID:32661350

Clinical Management and Therapeutic Strategies for the Thyroid-Associated Ophthalmopathy: Current and Future Perspectives., PMID:32567373

Datasheet

Document Download

Anti-NFKB1 Antibody (R3F44).pdf

 

$ 220
Product specifications
50 μg 220 100 μg 350

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Anti-NFKB1 Antibody (R3F44) [RHD35902]
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