Anti-TFE3 Antibody (R3F39)

Catalog No.

RHD34703

Species reactivity

Human

Host species

Mouse

Isotype

IgG1

Clonality

Monoclonal

Tested applications

IHC: 1:50-1:200

Target

TFE3, bHLHe33, BHLHE33, Transcription factor E3, Class E basic helix-loop-helix protein 33

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P19532

Applications

IHC

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R3F39

D-mannose suppresses the angiogenesis and progression of colorectal cancer., PMID:40259886

The nutrient-sensing Rag-GTPase complex in B cells controls humoral immunity via TFEB/TFE3-dependent mitochondrial fitness., PMID:39580479

Efficacy and safety of nivolumab monotherapy in patients with unresectable clear cell sarcoma and alveolar soft part sarcoma (OSCAR Trial/NCCH1510)., PMID:39077795

Unusual PEComa With PRCC :: TFE3 Fusion Mimicking Sinonasal Tract Melanoma., PMID:38975712

d-mannose targets PD-1 to lysosomal degradation and enhances T cell-mediated anti-tumor immunity., PMID:38615929

Rag-GTPase-TFEB/TFE3 axis controls B cell mitochondrial fitness and humoral immunity independent of mTORC1., PMID:38585731

The nutrient-sensing Rag-GTPase complex in B cells controls humoral immunity via TFEB/TFE3-dependent mitochondrial fitness., PMID:38463988

Melanotic PEComa: A Rare But Distinctive Subtype Analyzed in a Series of 7 Cases., PMID:38117287

Primary renal malignant epithelioid angiomyolipoma with distant metastasis: a case report and literature review., PMID:37675231

High-throughput and targeted drug screens identify pharmacological candidates against MiT-translocation renal cell carcinoma., PMID:37095531

Case Report: Two Cases of Soft-Tissue Sarcomas: High TMB as a Potential Predictive Biomarker for Anlotinib Combined With Toripalimab Therapy., PMID:35603147

Renal cancer associated with Xp11.2 translocation/TFE3 gene fusion: Clinicopathological analysis of 13 cases., PMID:35149286

Analyzing the morphological spectrum of epithelioid fibrous histiocytoma and the immunohistochemical performance of the ALK D5F3 and ALK1 clones., PMID:34929229

Loss of expression of YAP1 C-terminus as an ancillary marker for epithelioid hemangioendothelioma variant with YAP1-TFE3 fusion and other YAP1-related vascular neoplasms., PMID:34148063

Targeted therapy in Xp11 translocation renal cell carcinoma., PMID:33906362

Case Report: Ectopic Adrenocortical Carcinoma in the Ovary., PMID:33815299

Are tumor-associated micro-angiogenesis and lymphangiogenesis considered as the novel prognostic factors for patients with Xp11.2 translocation renal cell carcinoma?, PMID:33267784

Fluorescence in situ hybridization for WWTR1-CAMTA1 has higher sensitivity and specificity for epithelioid hemangioendothelioma diagnosis., PMID:32913529

CAMTA-1 Expression in 24 Cases of Hepatic Epithelioid Hemangioendothelioma in a Single Institute: Diagnostic Utility for Differential Diagnosis from Hepatic Angiosarcoma., PMID:31662570

[Immunohistochemical profile of renal cell tumours]., PMID:31530404

Nutrient deprivation and lysosomal stress induce activation of TFEB in retinal pigment epithelial cells., PMID:31160892

The incidence of renal cell carcinoma associated with Xp11.2 translocation/TFE3 gene fusion in Saudi adult patients with renal cancer: a retrospective tissue microarray analysis., PMID:30786687

Bilateral Xp11.2 translocation renal cell carcinoma: a case report., PMID:30458744

[Clinicopatholigic features of renal cell carcinoma associated with chromosome X inversion harboring gene fusions involving TFE3]., PMID:30107660

Response to Immune Checkpoint Inhibition in Two Patients with Alveolar Soft-Part Sarcoma., PMID:30018044

Multiple Eruptive Epithelioid Hemangiomas: A Subset of Cutaneous Cellular Epithelioid Hemangioma With Expression of FOS-B., PMID:29266025

Xp11 Translocation Renal Cell Carcinomas (RCCs) With RBM10-TFE3 Gene Fusion Demonstrating Melanotic Features and Overlapping Morphology With t(6;11) RCC: Interest and Diagnostic Pitfall in Detecting a Paracentric Inversion of TFE3., PMID:28288037

Methods to Monitor and Manipulate TFEB Activity During Autophagy., PMID:28237119

Alveolar Soft Part Sarcoma of the Female Genital Tract: A Morphologic, Immunohistochemical, and Molecular Cytogenetic Study of 10 Cases With Emphasis on its Distinction From Morphologic Mimics., PMID:28009610

FOSB is a Useful Diagnostic Marker for Pseudomyogenic Hemangioendothelioma., PMID:28009608

Practical issues in uterine pathology from banal to bewildering: the remarkable spectrum of smooth muscle neoplasia., PMID:26715170

Nuclear Expression of CAMTA1 Distinguishes Epithelioid Hemangioendothelioma From Histologic Mimics., PMID:26414223

Alveolar soft part sarcoma of lung: report of a unique case with emphasis on diagnostic utility of molecular genetic analysis for TFE3 gene rearrangement and immunohistochemistry for TFE3 antigen expression., PMID:26369552

Tubulocystic renal cell carcinoma is an entity that is immunohistochemically and genetically distinct from papillary renal cell carcinoma., PMID:26310887

Oncotargets in different renal cancer subtypes., PMID:25619751

Brain metastasis of crystal-deficient, CD68-positive alveolar soft part sarcoma: ultrastructural features and differential diagnosis., PMID:25268941

The preliminary experiences of translocation renal cell carcinoma and literature review., PMID:25002378

Renal tumors: diagnostic and prognostic biomarkers., PMID:24025522

Mammalian target of rapamycin pathway activity in alveolar soft part sarcoma., PMID:23871289

Diagnosis of Xp11 translocation renal cell carcinomas in adult patients under 50 years: interest and pitfalls of automated immunohistochemical detection of TFE3 protein., PMID:23246378

Immunohistochemical diagnosis of renal neoplasms., PMID:21204715

Altered transcription factor E3 expression in unclassified adult renal cell carcinoma indicates adverse pathological features and poor outcome., PMID:21070573

Xp11 translocation renal cell carcinoma (RCC): extended immunohistochemical profile emphasizing novel RCC markers., PMID:20679884

Vascular endothelial growth factor-targeted therapy for the treatment of adult metastatic Xp11.2 translocation renal cell carcinoma., PMID:20665500

Therapeutic vulnerability of an in vivo model of alveolar soft part sarcoma (ASPS) to antiangiogenic therapy., PMID:19636271

Perivascular epithelioid cell tumor with SFPQ/PSF-TFE3 gene fusion in a patient with advanced neuroblastoma., PMID:19606011

Alveolar soft part sarcoma presenting with cutaneous metastases: report of a case with immunohistochemical and molecular characterization., PMID:19539846

Hematopoietic- and neurologic-expressed sequence 1 (Hn1) depletion in B16.F10 melanoma cells promotes a differentiated phenotype that includes increased melanogenesis and cell cycle arrest., PMID:19427096

An aggressive course of Xp11 translocation renal cell carcinoma in a 28-year-old man., PMID:19298350

Response to sunitinib malate in advanced alveolar soft part sarcoma., PMID:19188185

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