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Anti-EIF2AK2 Antibody (R3F37)

Catalog #:   RHD34503 Specific References (14) DATASHEET
Host species: Mouse
Isotype: IgG1
Applications: ELISA, FCM, WB
Accession: P19525
Overview

Catalog No.

RHD34503

Species reactivity

Human

Host species

Mouse

Isotype

IgG1

Clonality

Monoclonal

Tested applications

ELISA: 1:10000, FCM: 1:200-1:400, WB: 1:500-1:2000

Target

Protein kinase R, PRKR, Eukaryotic translation initiation factor 2-alpha kinase 2, Interferon-induced, double-stranded RNA-activated protein kinase, Protein kinase RNA-activated, EIF2AK2, Tyrosine-protein kinase EIF2AK2, p68 kinase, PKR, P1/eIF-2A protein kinase, Interferon-inducible RNA-dependent protein kinase, eIF-2A protein kinase 2

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P19525

Applications

ELISA, FCM, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R3F37

Data Image
  • Flow Cytometry
    Flow cytometric analysis of A431 cells using EIF2AK2 mouse mAb (green) and negative control (red).
  • Western blot
    Western blot analysis using EIF2AK2 mouse mAb against A431 (1), MCF-7 (2), PC-12 (3) cell lysate.
References

Using the Ratio of Phosphorylated to Non-phosphorylated Forms of Stress Kinase PKR as a Potential Diagnostic Test for ME/CFS., PMID:40372675

Analysis of the relationships between interferon-stimulated genes and anti-SSA/Ro 60 antibodies in primary Sjögren's syndrome patients via multiomics and machine learning methods., PMID:39577221

Genetics and measles, mumps and rubella vaccine response in childhood and adolescence-A systematic review., PMID:38157324

IFN-beta and EIF2AK2 are potential biomarkers for interstitial lung disease in anti-MDA5 positive dermatomyositis., PMID:36912714

Hantaviruses use the endogenous host factor P58IPK to combat the PKR antiviral response., PMID:34653226

An integrated stress response via PKR suppresses HER2+ cancers and improves trastuzumab therapy., PMID:31086176

Visualization of Double-Stranded RNA Colocalizing With Pattern Recognition Receptors in Arenavirus Infected Cells., PMID:30087859

A Systems Vaccinology Approach Reveals Temporal Transcriptomic Changes of Immune Responses to the Yellow Fever 17D Vaccine., PMID:28687661

Imiquimod-induced autophagy is regulated by ER stress-mediated PKR activation in cancer cells., PMID:28601430

Presence of an interferon signature in individuals who are anti-nuclear antibody positive lacking a systemic autoimmune rheumatic disease diagnosis., PMID:28245862

Opposing Roles of Double-Stranded RNA Effector Pathways and Viral Defense Proteins Revealed with CRISPR-Cas9 Knockout Cell Lines and Vaccinia Virus Mutants., PMID:27334583

Insulin treatment promotes tyrosine phosphorylation of PKR and inhibits polyIC induced PKR threonine phosphorylation., PMID:26321373

Binding of the pathogen receptor HSP90AA1 to avibirnavirus VP2 induces autophagy by inactivating the AKT-MTOR pathway., PMID:25714412

Global transcriptional response to ISCOM-Matrix adjuvant at the site of administration and in the draining lymph node early after intramuscular injection in pigs., PMID:22426325

Datasheet
$ 220
Product specifications
50 μg 220 100 μg 350

Contact Information

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Distributor list

For research use only. Not for human or drug use.

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Anti-EIF2AK2 Antibody (R3F37) [RHD34503]
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