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Anti-ELK1 Antibody (R3F28)

Catalog #:   RHD33803 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG1
Applications: IHC
Accession: P19419
Overview

Catalog No.

RHD33803

Species reactivity

Human

Host species

Mouse

Isotype

IgG1

Clonality

Monoclonal

Tested applications

IHC: 1:200-1:1000

Target

ELK1, ETS domain-containing protein Elk-1

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P19419

Applications

IHC

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R3F28

Data Image
  • Immunohistochemical
    Immunohistochemical analysis of paraffin-embedded human brain tumor tissue, showing nuclear and cytoplasmic localization using ELK1 mouse mAb with DAB staining.
References

TMOD3 accelerated resistance to immunotherapy in KRAS-mutated pancreatic cancer through promoting autophagy-dependent degradation of ASCL4., PMID:39531951

High expression of RTEL1 predicates worse progression in gliomas and promotes tumorigenesis through JNK/ELK1 cascade., PMID:38532312

Autophagy activates EGR1 via MAPK/ERK to induce FGF2 in renal tubular cells for fibroblast activation and fibrosis during maladaptive kidney repair., PMID:37978868

Exploring dual effects of dinutuximab beta on cell death and proliferation of insulinoma., PMID:37802653

Guben Xiezhuo Decoction inhibits M1 polarization through the Raf1/p-Elk1 signaling axis to attenuate renal interstitial fibrosis., PMID:37716490

Adaptive c-Met-PLXDC2 Signaling Axis Mediates Cancer Stem Cell Plasticity to Confer Radioresistance-associated Aggressiveness in Head and Neck Cancer., PMID:37089864

Baicalin Inhibits Airway Smooth Muscle Cells Proliferation through the RAS Signaling Pathway in Murine Asthmatic Airway Remodeling Model., PMID:36814956

HTLV-1 intragenic viral enhancer influences immortalization phenotype in vitro, but is dispensable for persistence and disease development in animal models., PMID:35958554

Synovial fluid from end-stage osteoarthritis induces proliferation and fibrosis of articular chondrocytes via MAPK and RhoGTPase signaling., PMID:35176481

The regulation and function of CD20: an "enigma" of B-cell biology and targeted therapy., PMID:32482755

Phosphoproteome profiling provides insight into the mechanism of action for carvedilol-mediated cancer prevention., PMID:29626349

Arsenite-induced histone H3 modification and its effects on EGR1 and FOS expression in HeLa cells., PMID:29350772

IL-2 imprints human naive B cell fate towards plasma cell through ERK/ELK1-mediated BACH2 repression., PMID:29129929

Platelet-Derived Growth Factor Receptor α Contributes to Human Hepatic Stellate Cell Proliferation and Migration., PMID:28734947

Transforming Growth Factor-β-Activated Kinase 1 Is Required for Human FcγRIIIb-Induced Neutrophil Extracellular Trap Formation., PMID:27486461

Elk-1-mediated 15-lipoxygenase expression is required for hypoxia-induced pulmonary vascular adventitial fibroblast dynamics., PMID:27174674

Downregulated protein expression of transcriptional activator ELK-1 in atrial myocardium of chronic AF patients., PMID:26617947

Grifolin directly targets ERK1/2 to epigenetically suppress cancer cell metastasis., PMID:26516701

Involvement of the HCK and FGR src-family kinases in FCRL4-mediated immune regulation., PMID:25972488

An AUG codon conserved for protein function rather than translational initiation: the story of the protein sElk1., PMID:25036748

Heparin responses in vascular smooth muscle cells involve cGMP-dependent protein kinase (PKG)., PMID:24911927

Transcription factors involved in prostate gland adaptation to androgen deprivation., PMID:24886974

The endothelin-integrin axis is involved in macrophage-induced breast cancer cell chemotactic interactions with endothelial cells., PMID:24550382

Egr1 regulates lithium-induced transcription of the Period 2 (PER2) gene., PMID:23816566

A simple and efficient method to detect nuclear factor activation in human neutrophils by flow cytometry., PMID:23603868

A 28-kDa splice variant of NADPH oxidase-4 is nuclear-localized and involved in redox signaling in vascular cells., PMID:23393389

Silodosin inhibits noradrenaline-activated transcription factors Elk1 and SRF in human prostate smooth muscle., PMID:23226423

Breast tumor-associated osteoblast-derived CXCL5 increases cancer progression by ERK/MSK1/Elk-1/snail signaling pathway., PMID:23045282

Oncogenic Ras and B-Raf proteins positively regulate death receptor 5 expression through co-activation of ERK and JNK signaling., PMID:22065586

Neuronal nitric oxide contributes to neuroplasticity-associated protein expression through cGMP, protein kinase G, and extracellular signal-regulated kinase., PMID:21562256

Collagen fragments inhibit hyaluronan synthesis in skin fibroblasts in response to ultraviolet B (UVB): new insights into mechanisms of matrix remodeling., PMID:21454612

Barbituric acid derivative BAS 02104951 inhibits PKCε, PKCη, PKCε/RACK2 interaction, Elk-1 phosphorylation in HeLa and PKCε and η translocation in PC3 cells following TPA-induction., PMID:21186251

Regulation of Syk by phosphorylation on serine in the linker insert., PMID:20956537

Pigment epithelium-derived factor induces interleukin-10 expression in human macrophages by induction of PPAR gamma., PMID:20553736

Appearance of the pituitary factor Pit-1 increases chromatin remodeling at hypersensitive site III in the human GH locus., PMID:20395397

Identification and characterization of a novel 5 bp deletion in a putative insulin response element in the lipoprotein lipase gene., PMID:19563912

Follicle-stimulating hormone increases cholangiocyte proliferation by an autocrine mechanism via cAMP-dependent phosphorylation of ERK1/2 and Elk-1., PMID:19389804

Dopamine D1 receptor, but not dopamine D2 receptor, is a critical regulator for acute cocaine-enhanced gene expression., PMID:19228458

Increased phosphorylation of Ets-like transcription factor-1 in neurons of hypoxic preconditioned mice., PMID:19225881

BLNK binds active H-Ras to promote B cell receptor-mediated capping and ERK activation., PMID:19218240

Opposite effects of interleukin-1alpha and transforming growth factor-beta2 induce stage-specific regulation of junctional adhesion molecule-B gene in Sertoli cells., PMID:19164472

Advanced glycation end-product of low density lipoprotein activates the toll-like 4 receptor pathway implications for diabetic atherosclerosis., PMID:18818414

Erythropoietin enhancement of rat pancreatic tumor cell proliferation requires the activation of ERK and JNK signals., PMID:18550701

Differential activation of extracellular signal-regulated kinase 1 and a related complex in neuronal nuclei., PMID:18392730

Erk kinases link pre-B cell receptor signaling to transcriptional events required for early B cell expansion., PMID:18356083

Adaptor SKAP-55 binds p21 activating exchange factor RasGRP1 and negatively regulates the p21-ERK pathway in T-cells., PMID:18320039

Elk-1 associates with FAK, regulates the expression of FAK and MAP kinases as well as apoptosis in HK-2 cells., PMID:18247360

Elk-1 is a novel protein-binding partner for FAK, regulating phagocytosis in medfly hemocytes., PMID:17955497

Histone H1 is released from myonuclei and present in rimmed vacuoles with DNA in inclusion body myositis., PMID:17888663

Cell surface restriction of EGFR by a tenascin cytotactin-encoded EGF-like repeat is preferential for motility-related signaling., PMID:17708541

Datasheet

Document Download

Anti-ELK1 Antibody (R3F28).pdf

 

$ 220
Product specifications
50 μg 220 100 μg 350

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Anti-ELK1 Antibody (R3F28) [RHD33803]
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