Catalog No.
RHD15403
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a
Clonality
Monoclonal
Tested applications
ELISA: 1:10000, FCM: 1:200-1:400, IHC: 1:200-1:1000, WB: 1:500-1:2000
Target
GP150, Integrin beta-4, CD104, ITGB4
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P16144
Applications
ELISA, FCM, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3E31
Epithelial eversion, a collective rearrangement from apical-in to apical-out polarity, is initiated by α6β4 integrins and sustained by increased cell proliferation and anchorage-independence., PMID:40463241
Sialylated IgG-activated integrin β4-Src-Erk axis stabilizes c-Myc in a p300 lysine acetyltransferase-dependent manner to promote colorectal cancer liver metastasis., PMID:40010102
Localization of Lesions in Autoimmune Blistering Diseases Is Independent of Site-Specific Target Antigen Expression., PMID:40003627
ITGB4/CD104 mediates zika virus attachment and infection., PMID:39737945
Ocular Mucous Membrane Pemphigoid Demonstrates a Distinct Autoantibody Profile from Those of Other Autoimmune Blistering Diseases: A Preliminary Study., PMID:39584991
The Role of Serology in the Diagnosis of Ocular Predominant Mucous Membrane Pemphigoid and the Search for an Ocular-Specific Autoantigen., PMID:39241171
It is time to reconsider antibodies against integrin β4 in mucous membrane pemphigoid: Comment on 'Native collagen XVII complex ELISA: An approach for diagnosis and monitoring of anti-integrin β4 mucous membrane pemphigoid'., PMID:38940488
Involvement of BCR::ABL1 in laminin adhesion of Philadelphia chromosome-positive acute lymphoblastic leukemia through upregulation of integrin α6., PMID:38577721
Tumour cell-expressed PD-L1 reprograms lipid metabolism via EGFR/ITGB4/SREBP1c signalling in liver cancer., PMID:38455469
The Neural Progenitor Cell-Associated Transcription Factor FoxG1 Regulates Cardiac Epicardial Cell Proliferation., PMID:38239823
Native collagen XVII complex ELISA: An approach for diagnosis and monitoring of anti-integrin β4 mucous membrane pemphigoid., PMID:37908157
Native Autoantigen Complex Detects Pemphigoid Autoantibodies., PMID:36992950
Anti-β4 integrin autoantibodies in patients with mucous membrane pemphigoid: A retrospective analysis from a tertiary centre in Italy., PMID:36166640
A Case of Anti-BP180-type Mucous Membrane Pemphigoid with IgG and IgA Autoantibodies Showing Distinct Reactivities., PMID:36153720
Integrin alpha 6 is upregulated and drives hepatocellular carcinoma progression through integrin α6β4 complex., PMID:35657344
Targeting cancer stem cells via integrin β4., PMID:34504657
Flow-induced Reorganization of Laminin-integrin Networks Within the Endothelial Basement Membrane Uncovered by Proteomics., PMID:32332107
Galectin-1-Related Modulation of Trophoblast Endothelial Interactions by Integrins α1 and β1., PMID:32253734
Expression and distribution of CD151 as a partner of alpha6 integrin in male germ cells., PMID:32152440
Self-Renewal Capability of Hepatocytic Parental Progenitor Cells Derived From Adult Rat Liver Is Maintained Long Term When Cultured on Laminin 111 in Serum-Free Medium., PMID:31909353
Integrin β4-Targeted Cancer Immunotherapies Inhibit Tumor Growth and Decrease Metastasis., PMID:31843981
Characterization of organoid cultured human breast cancer., PMID:31829259
M. leprae interacts with the human epidermal keratinocytes, neonatal (HEKn) via the binding of laminin-5 with α-dystroglycan, integrin-β1, or -β4., PMID:31233498
Mucous Membrane Pemphigoid-Associated Malignancies: Case Series and a Brief Overview of the Literature., PMID:31106014
[Not Available]., PMID:31082464
Laminin γ2-enriched extracellular vesicles of oral squamous cell carcinoma cells enhance in vitro lymphangiogenesis via integrin α3-dependent uptake by lymphatic endothelial cells., PMID:30485433
Exogenous CXCL4 infusion inhibits macrophage phagocytosis by limiting CD36 signalling to enhance post-myocardial infarction cardiac dilation and mortality., PMID:30169632
Regulation of T cell afferent lymphatic migration by targeting LTβR-mediated non-classical NFκB signaling., PMID:30069025
Long-term Tumor Adaptation after Radiotherapy: Therapeutic Implications for Targeting Integrins in Prostate Cancer., PMID:30042176
β4-Integrin/PI3K Signaling Promotes Tumor Progression through the Galectin-3-N-Glycan Complex., PMID:29549127
Antibody-based cell-surface proteome profiling of metastatic breast cancer primary explants and cell lines., PMID:29498809
Combined treatment of pancreatic cancer xenograft with 90Y-ITGA6B4-mediated radioimmunotherapy and PI3K/mTOR inhibitor., PMID:29204055
Blocking integrin β1 decreases adhesion in chemoresistant urothelial cancer cell lines., PMID:29113179
Transforming growth factor β1 enhances adhesion of endometrial cells to mesothelium by regulating integrin expression., PMID:28760197
Aggregatibacter actinomycetemcomitans regulates the expression of integrins and reduces cell adhesion via integrin α5 in human gingival epithelial cells., PMID:28593565
[Current approaches to the morphologic diagnosis of different types of congenital epidermolysis bullosa]., PMID:28139597
Influenza Virus Infects Epithelial Stem/Progenitor Cells of the Distal Lung: Impact on Fgfr2b-Driven Epithelial Repair., PMID:27322618
Integrin β4 is a major target antigen in pure ocular mucous membrane pemphigoid., PMID:27193492
Generation of a monoclonal antibody recognizing the CEACAM glycan structure and inhibiting adhesion using cancer tissue-originated spheroid as an antigen., PMID:27098764
Protein profile of basal prostate epithelial progenitor cells--stage-specific embryonal antigen 4 expressing cells have enhanced regenerative potential in vivo., PMID:26849468
PHLPP negatively regulates cell motility through inhibition of Akt activity and integrin expression in pancreatic cancer cells., PMID:26760962
Vimentin-mediated regulation of cell motility through modulation of beta4 integrin protein levels in oral tumor derived cells., PMID:26646105
Integrins and haptoglobin: Molecules overexpressed in ovarian cancer., PMID:26549463
Mutant p53 promotes ovarian cancer cell adhesion to mesothelial cells via integrin β4 and Akt signals., PMID:26223322
Using immunofluorescence (antigen) mapping in the diagnosis and classification of epidermolysis bullosa: a first report from Iran., PMID:26220012
Integrin β4 and vinculin contained in exosomes are potential markers for progression of prostate cancer associated with taxane-resistance., PMID:25997717
Splicing abnormality of integrin β4 gene (ITGB4) due to nucleotide substitutions far from splice site underlies pyloric atresia-junctional epidermolysis bullosa syndrome., PMID:25728941
Integrin expression in esophageal squamous cell carcinoma: loss of the physiological integrin expression pattern correlates with disease progression., PMID:25398092
Paradoxical role of CBX8 in proliferation and metastasis of colorectal cancer., PMID:25360999
Up-regulation of integrin α6β4 expression by mitogens involved in dairy cow mammary development., PMID:25319126
For research use only. Not for human or drug use.
