Catalog No.
RHD12002
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
FCM: 1:200-1:400, IF: 1:200-1:1000, IHC: 1:200-1:1000
Target
NDPKA, NME1, NDP kinase A, Nucleoside diphosphate kinase A, Granzyme A-activated DNase, NM23, Metastasis inhibition factor nm23, GAAD, Tumor metastatic process-associated protein, NDK A, NM23-H1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P15531
Applications
FCM, IF, IHC
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3E08
[Progress in enrichment methods for protein N-phosphorylation]., PMID:38966971
Heat-shock protein 90α protects NME1 against degradation and suppresses metastasis of breast cancer., PMID:37731021
Glaucoma-Associated CDR1 Peptide Promotes RGC Survival in Retinal Explants through Molecular Interaction with Acidic Leucine Rich Nuclear Phosphoprotein 32A (ANP32A)., PMID:37509196
Phosphohistidine signaling promotes FAK-RB1 interaction and growth factor-independent proliferation of esophageal squamous cell carcinoma., PMID:36513743
Histidine kinase NME1 and NME2 are involved in TGF-β1-induced HSC activation and CCl4-induced liver fibrosis., PMID:32860079
The Potential Functional Roles of NME1 Histidine Kinase Activity in Neuroblastoma Pathogenesis., PMID:32392889
The Subcellular Localization and Oligomerization Preferences of NME1/NME2 upon Radiation-Induced DNA Damage., PMID:32235358
Analysis of 1- and 3-Phosphohistidine (pHis) Protein Modification Using Model Enzymes Expressed in Bacteria., PMID:31707652
NME proteins regulate class switch recombination., PMID:30411342
The relationship of NM23 (NME) metastasis suppressor histidine phosphorylation to its nucleoside diphosphate kinase, histidine protein kinase and motility suppression activities., PMID:29535799
The actions of NME1/NDPK-A and NME2/NDPK-B as protein kinases., PMID:29200201
Roles of KAI1 and nm23 in lymphangiogenesis and lymph metastasis of laryngeal squamous cell carcinoma., PMID:29187211
Meta-Analysis of the Relationship between NM23 Expression to Gastric Cancer Risk and Clinical Features., PMID:28401162
pHisphorylation: the emergence of histidine phosphorylation as a reversible regulatory modification., PMID:28129587
Monoclonal 1- and 3-Phosphohistidine Antibodies: New Tools to Study Histidine Phosphorylation., PMID:26140597
Metastasis suppressor NME1 regulates melanoma cell morphology, self-adhesion and motility via induction of fibronectin expression., PMID:25808322
NME1 suppression of endometrial stromal cells promotes angiogenesis in the endometriotic milieu via stimulating the secretion of IL-8 and VEGF., PMID:24133580
nm23-H1 is a negative regulator of TGF-β1-dependent induction of epithelial-mesenchymal transition., PMID:23137649
Transcatheter arterial chemoembolization enhances expression of Nm23-H1 and TIMP-2 in the tumor tissue of patients with hepatocellular carcinoma., PMID:21661431
A study on nm23-H1 expression in diffuse large B-cell lymphoma that was treated with CyclOBEAP plus rituximab therapy., PMID:20809421
Nm23-H1 suppresses hepatocarcinoma cell adhesion and migration on fibronectin by modulating glycosylation of integrin beta1., PMID:20618991
Significance of nm23 immunoexpression in the prognosis of renal cell carcinoma., PMID:20515575
Maspin and Nm23-H1 expression in colorectal cancer., PMID:20099971
Extracellular NM23-H1 protein inhibits the survival of primary cultured normal human peripheral blood mononuclear cells and activates the cytokine production., PMID:19655221
The SET complex acts as a barrier to autointegration of HIV-1., PMID:19266025
The nucleoside diphosphate kinase D (NM23-H4) binds the inner mitochondrial membrane with high affinity to cardiolipin and couples nucleotide transfer with respiration., PMID:18635542
NM23 as a prognostic biomarker in ovarian serous carcinoma., PMID:18408655
Expression of nm23-H1 in uveal melanoma., PMID:17885583
Prognostic impact of KI67, p53, human epithelial growth factor receptor 2, topoisomerase IIalpha, epidermal growth factor receptor, and nm23 expression of ovarian carcinomas and disseminated tumor cells in the bone marrow., PMID:17433065
[Study on the correlationship between the expression of nm23H1mRNA, TGF-beta1mRNA and tumor metastases, survival rate with prostate cancer]., PMID:17348207
NM23-H2, an estrogen receptor beta-associated protein, shows diminished expression with progression of atherosclerosis., PMID:17272673
Expression analysis of imbalanced genes in prostate carcinoma using tissue microarrays., PMID:17146477
Phase II study of the CPT-11, mitoxantrone and dexamethasone regimen in combination with rituximab in elderly patients with relapsed diffuse large B-cell lymphoma., PMID:16805825
Read-through transcript from NM23-H1 into the neighboring NM23-H2 gene encodes a novel protein, NM23-LV., PMID:16442775
Expression of nm23 antimetastatic gene product in parathyroid hyperplasia, adenoma and carcinoma. An immunohistological assessment., PMID:15951858
Increased lung metastasis in transgenic NM23-Null/SV40 mice with hepatocellular carcinoma., PMID:15928304
Analysis of nm23-H1 protein immunoreactivity in follicular thyroid tumors., PMID:15757202
Regulation of metastasis-suppressive gene Nm23-H1 on glycosyl-transferases involved in the synthesis of sialyl Lewis antigens., PMID:15696547
Oral alveolar soft-part sarcoma: review of literature and case report with immunohistochemistry study for prognostic markers., PMID:15599350
Alternative prognostic factors in pediatric embryonal rhabdomyosarcoma: Nm23 expression, proliferative activity and angiogenesis., PMID:15503477
Prognostic significance of nm23-H1 expression in esophageal squamous cell carcinoma., PMID:15296908
[Expression of sialylated carbohydrate antigens and nm23-H1 gene in prognosis of breast cancer]., PMID:15269984
[In vitro and in vivo study on proliferation of adnoid cystic carcinoma cell lines after nm23-h1. Introduction]., PMID:15190789
[Preparation and characterization of monoclonal antibodies against recombinant human NDPK-A]., PMID:15182630
Prognostic significance of nm23-H1 expression in oral squamous cell carcinoma., PMID:15150613
Prognostic significance of nm23 gene product expression in patients with colorectal carcinoma treated with radical intent., PMID:15138555
Co-downregulation of PTEN, KAI-1, and nm23-H1 tumor/metastasis suppressor proteins in non-small cell lung cancer., PMID:15129904
[The regulation of nm23-H1/NDPK-A in different processes of regional lymph node metastases of oral squamous cell carcinomas]., PMID:14513578
Nm23/NDP kinases in human male germ cells: role in spermiogenesis and sperm motility?, PMID:14499630
c-erbB-2, p53, and nm23 proteins as prognostic factors in patients with epithelial ovarian carcinoma., PMID:12950146
For research use only. Not for human or drug use.
