Anti-LIF Antibody (R3D77)

Catalog No.

RHD08001

Species reactivity

Human

Host species

Mouse

Isotype

IgG1

Clonality

Monoclonal

Tested applications

IHC: 1:25-1:200

Target

Emfilermin, D factor, HILDA, LIF, MLPLI, Melanoma-derived LPL inhibitor, Leukemia inhibitory factor, Differentiation-stimulating factor

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P15018

Applications

IHC

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R3D77

Quantifying Critical Quality Attributes of Protein Therapeutics by Sodium Dodecyl Sulfate-Capillary Gel Electrophoresis With Native Fluorescence Detection., PMID:40448278

PAT-on-a-chip: Miniaturization of analytical assays towards data-driven bioprocess development and optimization., PMID:40435762

IL1RAP Expression in Human Atherosclerosis: A Target of Novel Antibodies to Reduce Vascular Inflammation and Adhesion., PMID:40371594

Blocking LIF and PD-L1 enhances the antitumor efficacy of SBRT in murine PDAC models., PMID:40341024

Enhanced Separation of Extracellular Vesicles Using Capillary Isotachophoresis With Spacer Compounds., PMID:40189777

Elevated LIF and JAK-STAT activation drive severe COVID-19 in myeloma patients receiving the BCMA-CD3 bispecific antibody Elranatamab., PMID:39865264

Labeling of oligosaccharides and N-linked glycans by a rhodamine-based fluorescent tag for analysis by capillary electrophoresis with laser-induced fluorescence and mass spectrometry detection., PMID:39746290

Leukemia inhibitory factor (LIF) receptor amplifies pathogenic activation of fibroblasts in lung fibrosis., PMID:39636853

Rapid identification of primary atopic disorders (PAD) by a clinical landmark-guided, upfront use of genomic sequencing., PMID:39381601

Impact of anti leukemia inhibitory factor antibody on immune related gene expression in breast cancer Balb/c mouse model., PMID:39223212

Antagonist anti-LIF antibody derived from naive human scFv phage library inhibited tumor growth in mice., PMID:39169307

Cervical Cancer Evades the Host Immune System through the Inhibition of Type I Interferon and CXCL9 by LIF., PMID:39078728

A mechanistic PK/PD model of AZD0171 (anti-LIF) to support Phase II dose selection., PMID:39041713

Glycan clock of ageing-analytical precision and time-dependent inter- and i-individual variability., PMID:38877341

Leukemia inhibitory factor (LIF) receptor amplifies pathogenic activation of fibroblasts in lung fibrosis., PMID:38826450

ARTseq-FISH reveals position-dependent differences in gene expression of micropatterned mESCs., PMID:38724524

Engineered interleukin-6-derived cytokines recruit artificial receptor complexes and disclose CNTF signaling via the OSMR., PMID:38569939

Membrane Proteome-Wide Screening of Autoantibodies in CIDP Using Human Cell Microarray Technology., PMID:38484217

Protein kinase D drives the secretion of invasion mediators in triple-negative breast cancer cell lines., PMID:38323010

Leukemia inhibitory factor shortens primary cilia by upregulating C-C motif chemokine 2 in human neural stem/progenitor cells., PMID:37837427

Comparative Study of the Cytokine Profiles of Serum and Tissues from Patients with the Ossification of the Posterior Longitudinal Ligament., PMID:37509659

Tumor-intrinsic LKB1-LIF signaling axis establishes a myeloid niche to promote immune evasion and tumor growth., PMID:37502974

BMPRII+ neural precursor cells isolated and characterized from organotypic neurospheres: an in vitro model of human fetal spinal cord development., PMID:37488910

MTMR3 risk alleles enhance Toll Like Receptor 9-induced IgA immunity in IgA nephropathy., PMID:37414396

The effect of the anti-leukemia inhibitory factor on the immune system in the Balb/c mice bearing breast cancer induced with 4T1 cells., PMID:37393300

Comparative analysis of transferrin and IgG N-glycosylation in two human populations., PMID:36959410

Therapeutic Targeting of LIF Overcomes Macrophage-mediated Immunosuppression of the Local Tumor Microenvironment., PMID:36441800

Leukemia inhibitory factor is a therapeutic target for renal interstitial fibrosis., PMID:36335669

Relevance of leukaemia inhibitory factor to anti-melanoma differentiation-associated gene 5 antibody-positive interstitial lung disease., PMID:36326445

Microsphere amplified fluorescence and its application in sensing., PMID:36242905

Unambiguous identification of α-Gal epitopes in intact monoclonal antibodies by NMR spectroscopy., PMID:36239533

Potential biomarkers for diagnosis and assessment of disease activity in systemic lupus erythematosus., PMID:36029665

Phase I, first-in-human study of MSC-1 (AZD0171), a humanized anti-leukemia inhibitory factor monoclonal antibody, for advanced solid tumors., PMID:35921760

Prenatal exposure to nickel and atopic dermatitis at age 3 years: a birth cohort study with cytokine profiles., PMID:35841308

Tumor-derived CTF1 (cardiotrophin 1) is a critical mediator of stroma-assisted and autophagy-dependent breast cancer cell migration, invasion and metastasis., PMID:35722965

Development of a microfluidic droplet platform with an antibody-free magnetic-bead-based strategy for high through-put and efficient EVs isolation., PMID:35688075

The Pleiotropic role, functions and targeted therapies of LIF/LIFR axis in cancer: Old spectacles with new insights., PMID:35680099

The Alleviating Effect of Lagerstroemia indica Flower Extract on Stretch Marks through Regulation of Mast Cells., PMID:35209065

The role of antibody responses against glycans in bioprosthetic heart valve calcification and deterioration., PMID:35177855

Female-specific role of ciliary neurotrophic factor in the medial amygdala in promoting stress responses., PMID:35146079

Epithelial LIF signaling limits apoptosis and lung injury during bacterial pneumonia., PMID:35137631

Serum N-glycomics of a novel CDG-IIb patient reveals aberrant IgG glycosylation., PMID:35137040

[CHANGING IMMUNE STATUS IN PATIENTS WITH REACTIVE SPONDYLOARTHRITIS OF CHLAMIDIAL GENESIS]., PMID:35134772

Cancer-Associated Fibroblasts Regulate the Plasticity of Breast Cancer Stemness through the Production of Leukemia Inhibitory Factor., PMID:34947829

Capillary (Gel) Electrophoresis-Based Methods for Immunoglobulin (G) Glycosylation Analysis., PMID:34687009

Rapid Antibody Glycoengineering in CHO Cells Via RNA Interference and CGE-LIF N-Glycomics., PMID:34611868

Cocaine Detection by a Laser-Induced Immunofluorometric Biosensor., PMID:34562903

Hyper-IgE syndrome, 2021 update., PMID:34419355

Optimizing the Expression and Solubilization of an E. coli-Produced Leukemia Inhibitory Factor for Anti-LIF Antibody Production and Use Thereof for Contraception in Mice., PMID:34272681

[Qualitative determination of chiral compounds using capillary electrophoresis]., PMID:34213270

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