Catalog No.
RHD06202
Species reactivity
Human, Mouse
Host species
Mouse
Isotype
IgG2b
Clonality
Monoclonal
Tested applications
ELISA: 1:10000, FCM: 1:200-1:400, IF: 1:200-1:1000, IHC: 1:200-1:1000, WB: 1:500-1:2000
Target
Solute carrier family 2, facilitated glucose transporter member 4, GLUT-4, GLUT4, SLC2A4, Glucose transporter type 4, insulin-responsive
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P14672
Applications
ELISA, FCM, IF, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3D64
Secreted EMC10 inhibits muscle GLUT4 activity and glucose uptake in mice., PMID:40441535
Analysis of multiple insulin actions in single muscle fibres from insulin resistant mice reveals selective defect in endogenous GLUT4 translocation., PMID:40272884
A novel GLUT-4 electrochemical immunosensor based on a poly(thionine)-gold nanoparticle nanocomposite: Combining complex capacitance and dissolved oxygen to obtain an analytical signal., PMID:39919504
Acetylcysteine synergizes PD-1 blockers against colorectal cancer progression by promoting TCF1+PD1+CD8+ T cell differentiation., PMID:39420342
Immunoglobulin-Mediated Cardiac Protection From Ischemia/Reperfusion Injury in Diabetic Rats Is Associated With Endothelial Nitric Oxide Synthase/Glucose Transporter-4 Signaling Pathway., PMID:39240727
The Expression and Prognostic Value of Multiple Glucose Transporters in Cutaneous Melanoma., PMID:39197896
Generation of antibodies to an extracellular region of the transporters Glut1/Glut4 by immunization with a designed antigen., PMID:38199569
Mulberry leaf multi-components exert hypoglycemic effects through regulation of the PI-3K/Akt insulin signaling pathway in type 2 diabetic rats., PMID:37939911
NAT10/ac4C/FOXP1 Promotes Malignant Progression and Facilitates Immunosuppression by Reprogramming Glycolytic Metabolism in Cervical Cancer., PMID:37818745
Diane-35 and metformin therapy in rats with endometrial lesions induced by dihydrotestosterone exposure., PMID:37082665
Effects of CX3CR1 and CXCR2 antagonists on running-dependent intramuscular neutrophil recruitments and myokine upregulation., PMID:36856190
Expression of GLUT4 and FAP in urothelial bladder carcinoma: correlation with angiogenesis and clinicopathological characteristics., PMID:36155866
The female syndecan-4-/- heart has smaller cardiomyocytes, augmented insulin/pSer473-Akt/pSer9-GSK-3β signaling, and lowered SCOP, pThr308-Akt/Akt and GLUT4 levels., PMID:36092718
ALKBH5-Mediated m6A Demethylation of GLUT4 mRNA Promotes Glycolysis and Resistance to HER2-Targeted Therapy in Breast Cancer., PMID:36069931
Endocytosis Assays Using Cleavable Fluorescent Dyes., PMID:35819767
Targeting cholesteryl ester accumulation in the heart improves cardiac insulin response., PMID:35709652
A Novel Partial PPARγ Agonist Has Weaker Lipogenic Effect in Adipocytes and Stimulates GLUT4 Translocation in Skeletal Muscle Cells via AMPK-Dependent Signaling., PMID:34736259
High-intensity infrasound effects on glucose metabolism in rats., PMID:34446814
Clozapine Worsens Glucose Intolerance, Nonalcoholic Fatty Liver Disease, Kidney Damage, and Retinal Injury and Increases Renal Reactive Oxygen Species Production and Chromium Loss in Obese Mice., PMID:34206460
Myosin 1c: A novel regulator of glucose uptake in brown adipocytes., PMID:33965643
Vehicle emissions-exposure alters expression of systemic and tissue-specific components of the renin-angiotensin system and promotes outcomes associated with cardiovascular disease and obesity in wild-type C57BL/6 male mice., PMID:33948438
SARS-CoV-2 proteins regulate inflammatory, thrombotic and diabetic responses in human arterial fibroblasts., PMID:33895357
Autoimmune activation of the GnRH receptor induces insulin resistance independent of obesity in a female rat model., PMID:33356018
Current understanding of glucose transporter 4 expression and functional mechanisms., PMID:33274014
Histone deacetylase 5 regulates interleukin 6 secretion and insulin action in skeletal muscle., PMID:32771698
Cellular Assays for Measuring Dynamin Activity in Muscle Cells., PMID:32529371
Effect of β-sitosterol on glucose homeostasis by sensitization of insulin resistance via enhanced protein expression of PPRγ and glucose transporter 4 in high fat diet and streptozotocin-induced diabetic rats., PMID:32124158
A Role for Oncostatin M in the Impairment of Glucose Homeostasis in Obesity., PMID:31606738
Klotho induces insulin resistance possibly through interference with GLUT4 translocation and activation of Akt, GSK3β, and PFKfβ3 in 3T3-L1 adipocyte cells., PMID:31516514
ABCA1 and metabolic syndrome; a review of the ABCA1 role in HDL-VLDL production, insulin-glucose homeostasis, inflammation and obesity., PMID:31336517
Targeting the glucagon receptor improves cardiac function and enhances insulin sensitivity following a myocardial infarction., PMID:30626440
Fibroblast growth factor-1 as a mediator of paracrine effects of canine adipose tissue-derived mesenchymal stem cells on in vitro-induced insulin resistance models., PMID:30445954
High Glucose Promotes Epithelial-Mesenchymal Transition of Uterus Endometrial Cancer Cells by Increasing ER/GLUT4-Mediated VEGF Secretion., PMID:30308493
Immunohistochemical Evaluation of GLUT-3 and GLUT-4 in Oral Epithelial Dysplasia and Oral Squamous Cell Carcinoma., PMID:30049187
Membrane Topology of Trafficking Regulator of GLUT4 1 (TRARG1)., PMID:29787242
Isolation of state-dependent monoclonal antibodies against the 12-transmembrane domain glucose transporter 4 using virus-like particles., PMID:29769329
Interleukin-4 Restores Insulin Sensitivity in Lipid-Induced Insulin-Resistant Adipocytes., PMID:29738684
Liraglutide ameliorates palmitate-induced insulin resistance through inhibiting the IRS-1 serine phosphorylation in mouse skeletal muscle cells., PMID:29374854
Proximity Ligation Assay to Study the GLUT4 Membrane Trafficking Machinery., PMID:29218528
Glucose Transport: Methods for Interrogating GLUT4 Trafficking in Adipocytes., PMID:29218527
GLUT4 Translocation in Single Muscle Cells in Culture: Epitope Detection by Immunofluorescence., PMID:29218526
Inhibition of insulin/PI3K/AKT signaling decreases adipose Sortilin 1 in mice and 3T3-L1 adipocytes., PMID:28844948
PROTECTIVE EFFECT OF CAMEL MILK AS ANTI-DIABETIC SUPPLEMENT: BIOCHEMICAL, MOLECULAR AND IMMUNOHISTOCHEMICAL STUDY., PMID:28638873
Characterization of the CLASP2 Protein Interaction Network Identifies SOGA1 as a Microtubule-Associated Protein., PMID:28550165
Crossreactivity of an Antiserum Directed to the Gram-Negative Bacterium Neisseria gonorrhoeae with the SNARE-Complex Protein Snap23 Correlates to Impaired Exocytosis in SH-SY5Y Cells., PMID:28462458
Systematic investigation on the intracellular trafficking network of polymeric nanoparticles., PMID:28225130
DNA Damage and the Activation of the p53 Pathway Mediate Alterations in Metabolic and Secretory Functions of Adipocytes., PMID:27388216
Expression Profiling of Ascorbic Acid-Related Transporters in Human and Mouse Eyes., PMID:27367512
Erythropoietin ameliorates hyperglycemia in type 1-like diabetic rats., PMID:27350742
Exercise-induced increase in IL-6 level enhances GLUT4 expression and insulin sensitivity in mouse skeletal muscle., PMID:27040770
For research use only. Not for human or drug use.
