Anti-MTHFD2 Antibody (R3D50)

Catalog No.

RHD02701

Species reactivity

Human

Host species

Mouse

Isotype

IgG1

Clonality

Monoclonal

Tested applications

IHC: 1:100-1:200, IP: 1:100-1:200, WB: 1:500-1:1000

Target

NMDMC, MTHFD2, Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P13995

Applications

IHC, IP, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R3D50

EP300-mediated H3 acetylation elevates MTHFD2 expression to reduce mitochondrial dysfunction in lipopolysaccharide-induced tubular epithelial cells., PMID:39230047

Metabolic determinants of germinal center B cell formation and responses., PMID:39060389

A Randomized Phase III Study of Arfolitixorin versus Leucovorin with 5-Fluorouracil, Oxaliplatin, and Bevacizumab for First-Line Treatment of Metastatic Colorectal Cancer: The AGENT Trial., PMID:38059497

Gene variants in the folate pathway are associated with increased levels of folate receptor autoantibodies., PMID:29732742

Cell line profiling to improve monoclonal antibody production., PMID:24249214

Document Download

Anti-MTHFD2 Antibody (R3D50).pdf