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Anti-MTHFD2 Antibody (R3D50)

Catalog #:   RHD02701 Specific References (5) DATASHEET
Host species: Mouse
Isotype: IgG1
Applications: IHC, IP, WB
Accession: P13995
Overview

Catalog No.

RHD02701

Species reactivity

Human

Host species

Mouse

Isotype

IgG1

Clonality

Monoclonal

Tested applications

IHC: 1:100-1:200, IP: 1:100-1:200, WB: 1:500-1:1000

Target

NMDMC, MTHFD2, Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P13995

Applications

IHC, IP, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R3D50

Data Image
  • Immunohistochemical
    IHC-P analysis of kidney tissue by MTHFD2 antibody (RHD02701). IHC-P was performed using sections of the formalin-fixed paraffin-embedded kidney tissue;Result: Cells in tubules are positively stained at the cytoplasm (distal tubules stronger than proximal tubules ).
  • Immunoprecipitation
    Lane 1: A-431 lysate ; Lane 2: MTHFD2 immunoprecipitated from A-431 lysate by RHD02701;Lane 3: The same as Lane 2 but use IgG isotype control antibody ;Result: RHD02701 can immunoprecipitate MTHFD2;
  • Western blot
    Western blot analysis using MTHFD2 mouse mAb against A-431 lysate
References

EP300-mediated H3 acetylation elevates MTHFD2 expression to reduce mitochondrial dysfunction in lipopolysaccharide-induced tubular epithelial cells., PMID:39230047

Metabolic determinants of germinal center B cell formation and responses., PMID:39060389

A Randomized Phase III Study of Arfolitixorin versus Leucovorin with 5-Fluorouracil, Oxaliplatin, and Bevacizumab for First-Line Treatment of Metastatic Colorectal Cancer: The AGENT Trial., PMID:38059497

Gene variants in the folate pathway are associated with increased levels of folate receptor autoantibodies., PMID:29732742

Cell line profiling to improve monoclonal antibody production., PMID:24249214

Datasheet

Document Download

Anti-MTHFD2 Antibody (R3D50).pdf

 

$ 220
Product specifications
50 μg 220 100 μg 350

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For research use only. Not for human or drug use.

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Anti-MTHFD2 Antibody (R3D50) [RHD02701]
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