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Anti-CD107b/LAMP2 Antibody (R3D13)

Catalog #:   RHC97405 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG2b
Applications: ELISA, FCM, IHC, WB
Accession: P13473
Overview

Catalog No.

RHC97405

Species reactivity

Human, Mouse, Rat

Host species

Mouse

Isotype

IgG2b

Clonality

Monoclonal

Tested applications

ELISA: 1:10000, FCM: 1:200-1:400, IHC: 1:200-1:1000, WB: 1:500-1:2000

Target

LGP-96, CD107b, LAMP2, CD107 antigen-like family member B, Lysosome-associated membrane glycoprotein 2, Lysosome-associated membrane protein 2, LAMP-2

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P13473

Applications

ELISA, FCM, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R3D13

Data Image
  • Flow Cytometry
    Flow cytometric analysis of Ramos cells using CD107b mouse mAb (green) and negative control (red).
  • Immunohistochemical
    Immunohistochemical analysis of paraffin-embedded human endometrial cancer tissues using CD107b mouse mAb with DAB staining.
  • Western blot
    Western blot analysis using CD107b mouse mAb against U937 (1), HepG2 (2), RAW264.7 (3), NIH3T3 (4), C6 (5), and T47D (6) cell lysate.
References

In vivo labeling reveals that degranulation is increased under supraphysiological TCR stimulation, but not infection, in CD8+ T cells from old mice., PMID:40478430

Enhanced therapeutic efficacy of anti-PD-1 blockade by targeting LAMP2A inhibits lysosomal degradation of STING and TBK1., PMID:40083918

Lysosomes accumulate at the perinuclear region of muscle cells during chick myogenesis., PMID:39252384

Immunoexpression Pattern of Autophagy-Related Proteins in Human Congenital Anomalies of the Kidney and Urinary Tract., PMID:38999938

Comprehensive knockout analysis of the RAB family small GTPases reveals an overlapping role of RAB2 and RAB14 in autophagosome maturation., PMID:38953305

Anti-LAMP-2 Antibody Seropositivity in Children with Primary Systemic Vasculitis Affecting Medium- and Large-Sized Vessels., PMID:38612581

Knockout validation of LAMP2A antibodies for immunostaining in human cancer cells., PMID:37194363

Recent topics related to etiology and clinical manifestations of cutaneous arteritis., PMID:36300176

Immunohistochemical Detection of the Chaperone-Mediated Autophagy Markers LAMP2A and HSPA8 in Formalin-Fixed and Paraffin-Embedded Tissues., PMID:36152248

Typical cutaneous small-vessel vasculitis induced by combined injection of antiphosphatidylserine/prothrombin complex antibody and anti-LAMP-2 antibody in normal rats., PMID:35876151

The Association of Serum Anti-Lysosomal-Associated Membrane Protein-2 Antibody with Vasculitis Combined with Hypertension., PMID:35356030

Chaperone-Mediated Autophagy Markers LAMP2A and HSPA8 in Advanced Non-Small Cell Lung Cancer after Neoadjuvant Therapy., PMID:34685711

Implication of a lysosomal antigen in the pathogenesis of lupus erythematosus., PMID:33932829

Autoantibodies Against Lysosome Associated Membrane Protein-2 (LAMP-2) in Pediatric Chronic Primary Systemic Vasculitis., PMID:33613565

Alterations of serum levels of plasminogen, TNF-α, and IDO in granulomatosis with polyangiitis patients., PMID:33427113

Chaperone-Mediated Autophagy Markers LAMP2A and HSC70 Are Independent Adverse Prognostic Markers in Primary Resected Squamous Cell Carcinomas of the Lung., PMID:33029283

Chaperone-Mediated Autophagy after Spinal Cord Injury., PMID:32233738

Systemic AAV9.LAMP2B injection reverses metabolic and physiologic multiorgan dysfunction in a murine model of Danon disease., PMID:32188720

Relationship between lysosomal-associated membrane protein-2 and anti-phosphatidylserine/prothrombin complex antibody in the pathogenesis of cutaneous vasculitis., PMID:31994486

Pyrroloquinoline quinine ameliorates doxorubicin-induced autophagy-dependent apoptosis via lysosomal-mitochondrial axis in vascular endothelial cells., PMID:31226464

Tumor cells induce LAMP2a expression in tumor-associated macrophage for cancer progression., PMID:30711520

Serum lysosomal-associated membrane protein-2 levels are increased in small and medium-vessel vasculitis, especially in polyarteritis nodosa., PMID:30620279

Characterization of the "Autophagic Flux" in Prostate Cancer Tissue Biopsies by LC3A/LAMP2a Immunofluorescence and Confocal Microscopy., PMID:30610722

Host cell protein LAMP-2 is the receptor for Trypanosoma cruzi surface molecule gp82 that mediates invasion., PMID:30609224

Development of a novel anti-HER2 scFv by ribosome display and in silico evaluation of its 3D structure and interaction with HER2, alone and after fusion to LAMP2B., PMID:30225583

Rituximab impedes natural killer cell function in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis patients: A pilot in vitro investigation., PMID:29587879

Cell surface markers for the identification and study of human naive pluripotent stem cells., PMID:29227830

Surface LAMP-2 Is an Endocytic Receptor That Diverts Antigen Internalized by Human Dendritic Cells into Highly Immunogenic Exosomes., PMID:28607115

Lysosomal Acidification in Cultured Astrocytes Using Nanoparticles., PMID:28456982

Cytotoxic CD8+ T cell ablation enhances the capacity of regulatory T cells to delay viral elimination in Theiler's murine encephalomyelitis., PMID:28452087

Identification of Putative Receptors for the Novel Adipokine CTRP3 Using Ligand-Receptor Capture Technology., PMID:27727322

Identification of LAMP2 Mutations in Early-Onset Danon Disease With Hypertrophic Cardiomyopathy by Targeted Next-Generation Sequencing., PMID:27460667

Effect of secondary anchor amino acid substitutions on the immunogenic properties of an HLA-A*0201-restricted T cell epitope derived from the Trypanosoma cruzi KMP-11 protein., PMID:26854383

Chaperone-mediated autophagy regulates proliferation by targeting RND3 in gastric cancer., PMID:26761524

Prosthetic Antigen Receptors., PMID:26230248

Heparin enhances uptake of platelet factor 4/heparin complexes by monocytes and macrophages., PMID:25960020

Proteomics urine analysis of pregnant women suffering from multiple sclerosis., PMID:25793971

Neutrophil extracellular trap formation is associated with autophagy-related signalling in ANCA-associated vasculitis., PMID:25644394

Emerging concepts in the pathogenesis of antineutrophil cytoplasmic antibody-associated vasculitis., PMID:25629443

Early and irreversible recurrence MPO-ANCA-positive glomerulonephritis after renal transplantation., PMID:25345380

Successful treatment with plasma exchange for ANCA-negative pauci-immune crescentic glomerulonephritis with D-negative hemolytic uremic syndrome., PMID:25074840

Reproducibility and efficiency of serum-derived exosome extraction methods., PMID:24956264

Lipopeptides are signaled by Toll-like receptor 1, 2 and 6 in endolysosomes., PMID:24860120

Autoantibodies to hLAMP-2 in ANCA-negative pauci-immune focal necrotizing GN., PMID:24203998

[Neurological involvement in Wegener's granulomatosis]., PMID:24200609

Identification of a primary biliary cirrhosis associated protein as lysosome-associated membrane protein-2., PMID:24007661

Transplantation of human umbilical mesenchymal stem cells cures the corneal defects of mucopolysaccharidosis VII mice., PMID:23897660

Calpain 1 induce lysosomal permeabilization by cleavage of lysosomal associated membrane protein 2., PMID:23747342

Lysosomal-associated membrane protein-2 plays an important role in the pathogenesis of primary cutaneous vasculitis., PMID:23704322

Pathogenesis of rapidly progressive glomerulonephritis: what do we learn?, PMID:23689582

Datasheet
$ 220
Product specifications
50 μg 220 100 μg 350

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For research use only. Not for human or drug use.

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Anti-CD107b/LAMP2 Antibody (R3D13) [RHC97405]
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