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Anti-HSPA8 Antibody (R3C45)

Catalog #:   RHC85603 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG1
Applications: IHC, WB
Accession: P11142
Overview

Catalog No.

RHC85603

Species reactivity

Human, Mouse, Rat

Host species

Mouse

Isotype

IgG1

Clonality

Monoclonal

Tested applications

IHC: 1:50-1:100, WB: 1:500-1:1000

Target

Lipopolysaccharide-associated protein 1, HSPA10, Heat shock 70 kDa protein 8, LPS-associated protein 1, LAP-1, HSP73, HSC70, HSPA8, Heat shock cognate 71 kDa protein

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P11142

Applications

IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.5% BSA, 0.05% Sodium Azide and 50% Glycerol.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R3C45

Data Image
  • Immunohistochemical
    Immunohistochemistry analysis of paraffin-embedded Human Breast Caricnoma using Hsc70 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
  • Western blot
    Western blot analysis of Hsc70 in Hela, A549, HL-60, U2OS, C6 lysates using Hsc70 antibody
References

Anti-TNFα and Anti-IL-1β Monoclonal Antibodies Preserve BV-2 Microglial Homeostasis Under Hypoxia by Mitigating Inflammatory Reactivity and ATF4/MAPK-Mediated Apoptosis., PMID:40338234

Rituximab-Chidamide combination chemotherapy enhances autophagy to overcome drug resistance in diffuse large B-cell lymphoma., PMID:40258315

Proximity proteomics reveals unique and shared pathological features between multiple system atrophy and Parkinson's disease., PMID:40122840

Comparing alpha-synuclein-interactomes between multiple systems atrophy and Parkinson's disease reveals unique and shared pathological features., PMID:39345456

SHISA3 Reprograms Tumor-Associated Macrophages Toward an Antitumoral Phenotype and Enhances Cancer Immunotherapy., PMID:39054639

Hsc70 promotes anti-tumor immunity by targeting PD-L1 for lysosomal degradation., PMID:38762492

Identification of key genes and imbalance of immune cell infiltration in immunoglobulin A associated vasculitis nephritis by integrated bioinformatic analysis., PMID:37026011

The Effect of the Histone Chaperones HSPA8 and DEK on Tumor Immunity in Hepatocellular Carcinoma., PMID:36768989

Immunohistochemical Detection of the Chaperone-Mediated Autophagy Markers LAMP2A and HSPA8 in Formalin-Fixed and Paraffin-Embedded Tissues., PMID:36152248

Heat Shock Protein Member 8 (HSPA8) Is Involved in Porcine Reproductive and Respiratory Syndrome Virus Attachment and Internalization., PMID:35138165

Proteomic identification of arginine-methylated proteins in colon cancer cells and comparison of messenger RNA expression between colorectal cancer and adjacent normal tissues., PMID:35081685

Stress-induced phosphoprotein 1 restrains spinal cord ischaemia-reperfusion injury by modulating NF-κB signalling., PMID:34734476

Chaperone-Mediated Autophagy Markers LAMP2A and HSPA8 in Advanced Non-Small Cell Lung Cancer after Neoadjuvant Therapy., PMID:34685711

Extracellular Vesicle and Particle Biomarkers Define Multiple Human Cancers., PMID:32795414

Heat Shock Protein Member 8 Is an Attachment Factor for Infectious Bronchitis Virus., PMID:32765462

Functional surface proteomic profiling reveals the host heat-shock protein A8 as a mediator of Lichtheimia corymbifera recognition by murine alveolar macrophages., PMID:32583550

Chaperone-assisted selective autophagy in healthy and papillomavirus-associated neoplastic urothelium of cattle., PMID:29981700

Small and big Hodgkin-Reed-Sternberg cells of Hodgkin lymphoma cell lines L-428 and L-1236 lack consistent differences in gene expression profiles and are capable to reconstitute each other., PMID:28505189

Fatty acid synthase inhibits the O-GlcNAcase during oxidative stress., PMID:28232487

The Mesenchymal Precursor Cell Marker Antibody STRO-1 Binds to Cell Surface Heat Shock Cognate 70., PMID:28026090

Chaperone-mediated autophagy regulates proliferation by targeting RND3 in gastric cancer., PMID:26761524

Circulating Autoantibodies in Age-Related Macular Degeneration Recognize Human Macular Tissue Antigens Implicated in Autophagy, Immunomodulation, and Protection from Oxidative Stress and Apoptosis., PMID:26717306

Serological proteome analysis reveals new specific biases in the IgM and IgG autoantibody repertoires in autoimmune polyendocrine syndrome type 1., PMID:26312540

Serum reactivity against herpes simplex virus type 1 UL48 protein in Behçet's disease patients and a Behçet's disease-like mouse model., PMID:25916670

Electrophoretic and immunocytochemical analysis of Hsp72 and Hsp73 expression in heat-stressed mouse testis and epididymis., PMID:23352621

70-kDa heat shock cognate protein hsc70 mediates calmodulin-dependent nuclear import of the sex-determining factor SRY., PMID:23235156

Sustained productivity in recombinant Chinese hamster ovary (CHO) cell lines: proteome analysis of the molecular basis for a process-related phenotype., PMID:21781345

Comment to: Humanization of a mouse monoclonal antibody directed against a cell surface-exposed epitope of membrane-associated heat shock protein 70 (Hsp70)., PMID:20668964

Exosomes from human lymphoblastoid B cells express enzymatically active CD38 that is associated with signaling complexes containing CD81, Hsc-70 and Lyn., PMID:20570673

Hispolon promotes MDM2 downregulation through chaperone-mediated autophagy., PMID:20540933

Insulin-degrading enzyme binds to the nonglycosylated precursor of varicella-zoster virus gE protein found in the endoplasmic reticulum., PMID:19864391

Chromatin-associated proteins HMGB1/2 and PDIA3 trigger cellular response to chemotherapy-induced DNA damage., PMID:19372559

Effects of oviductal proteins, including heat shock 70 kDa protein 8, on survival of ram spermatozoa over 48 h in vitro., PMID:19261218

Heat shock cognate protein 70 contributes to Brucella invasion into trophoblast giant cells that cause infectious abortion., PMID:19055850

Effects of HSPA8, an evolutionarily conserved oviductal protein, on boar and bull spermatozoa., PMID:18996976

Long-term exposure to low lithium concentrations stimulates proliferation, modifies stress protein expression pattern and enhances resistance to oxidative stress in SH-SY5Y cells., PMID:18688712

Critical role of extracellular heat shock cognate protein 70 in the myocardial inflammatory response and cardiac dysfunction after global ischemia-reperfusion., PMID:18441202

The clinical significance of anti-heat shock cognate protein 71 antibody in myasthenia gravis., PMID:17981040

Heat shock 70-kDa protein 8 isoform 1 is expressed on the surface of human embryonic stem cells and downregulated upon differentiation., PMID:16100000

Different sources of "help" facilitate the antibody response to hepatitis D virus delta antigen., PMID:15776288

Effects of nickel poisoning on expression pattern of the 72/73 and 94 kDa stress proteins in rat organs and in the COS-7, HepG2, and A549 cell lines., PMID:15736156

Identification of proteins binding the native tubulin dimer., PMID:15629426

Intracellular localization of constitutive and inducible heat shock protein 70 in rat liver after in vivo heat stress., PMID:15543931

Novel biomarker of HTLV-1-associated disease: specific appearance of antibody recognizing the receptor-binding site on HTLV-1 envelope protein., PMID:15504252

N-myristoyltransferase inhibitor protein is homologous to heat shock cognate protein 70., PMID:15156568

Gene expression profiles define a key checkpoint for type 1 diabetes in NOD mice., PMID:14747287

Continuous enhanced expression of Hsc70 but not Hsp70 in rheumatoid arthritis synovial tissue., PMID:14730603

Antibodies to HSP-70 in normal donors and autoimmune hearing loss patients., PMID:14520104

T-cell receptor variable gamma chain gene expression in the interaction between rat gammadelta-type T cells and heat-shock protein 70-like molecule., PMID:12825896

Prevalence of HSP47 antigen and autoantibodies to HSP47 in the sera of patients with mixed connective tissue disease., PMID:12659832

Datasheet

Document Download

Anti-HSPA8 Antibody (R3C45).pdf

 

$ 220
Product specifications
50 μg 220 100 μg 350

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Anti-HSPA8 Antibody (R3C45) [RHC85603]
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