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Anti-CHGA Antibody (R3C21)

Catalog #:   RHC82706 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG1
Applications: ELISA, WB
Accession: P10645
Overview

Catalog No.

RHC82706

Species reactivity

Human, Mouse

Host species

Mouse

Isotype

IgG1

Clonality

Monoclonal

Tested applications

ELISA: 1:10000, WB: 1:500-1:2000

Target

Vasostatin I, Pituitary secretory protein I, Vasostatin II, Chromogranin-A, SP-I, CgA, SL21, CHGA

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P10645

Applications

ELISA, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R3C21

Data Image
  • Western blot
    Western blot analysis using CHGA mouse mAb against MOLT4 (1), SK-N-SH (2), HepG2 (3), PC-12 (4), and C6 (5) cell lysate.
References

[Establishment of a sandwich ELISA method for CHGA in saliva samples and its preliminary application in stress detection]., PMID:40260565

Enhanced Association of Novel Cardiovascular Biomarkers Fetuin-A and Catestatin with Serological and Inflammatory Markers in Rheumatoid Arthritis Patients., PMID:39337398

CD4+ T cells reactive to a hybrid peptide from insulin-chromogranin A adopt a distinct effector fate and are pathogenic in autoimmune diabetes., PMID:39214091

The Significance of Insulinoma-Associated Protein 1 in the Pathological Diagnosis of Small-Cell Lung Cancer in Biopsy Specimens., PMID:38192158

[Pancreatic β-cell dedifferentiation detected by flow cytometry]., PMID:36456511

Histological, histochemical, ultrastructural and immunohistochemical identification and characterization of the neurosecretory cells of the adult rabbit's adrenal medulla., PMID:35119700

Chromogranin A Deficiency Confers Protection From Autoimmune Diabetes via Multiple Mechanisms., PMID:34497137

Novel Insight in Idiopathic Normal Pressure Hydrocephalus (iNPH) Biomarker Discovery in CSF., PMID:34360799

Chromogranin Serves as Novel Biomarker of Endocrine and Gastric Autoimmunity., PMID:32436949

A Hybrid Insulin Epitope Maintains High 2D Affinity for Diabetogenic T Cells in the Periphery., PMID:31806623

Spatiotemporal Regulation of Tumor Angiogenesis by Circulating Chromogranin A Cleavage and Neuropilin-1 Engagement., PMID:30796053

NordiQC Assessments of Chromogranin A Immunoassays., PMID:30653032

Effective preparation of a monoclonal antibody against human chromogranin A for immunohistochemical diagnosis., PMID:29728076

Blocking the Feedback Loop between Neuroendocrine Differentiation and Macrophages Improves the Therapeutic Effects of Enzalutamide (MDV3100) on Prostate Cancer., PMID:29191973

Alcohol Feeding in Mice Promotes Colonic Hyperpermeability and Changes in Colonic Organoid Stem Cell Fate., PMID:28992396

Neuroendocrine differentiation in basal cell carcinoma., PMID:28548901

Chromogranin A regulates vesicle storage and mitochondrial dynamics to influence insulin secretion., PMID:28220294

Neuroendocrine Differentiation in Thymic Carcinomas: A Diagnostic Pitfall: An Immunohistochemical Analysis of 27 Cases., PMID:27124922

Long-Term Insulin Independence in Type 1 Diabetes Mellitus Using a Simplified Autologous Stem Cell Transplant., PMID:26859103

Autoantibodies to chromogranin A are potential diagnostic biomarkers for non-small cell lung cancer., PMID:26186986

Comparison of chromogranin A (CgA) levels in serum and plasma (EDTA2K) and the respective reference ranges in healthy males., PMID:25754282

Enteroendocrine cells are specifically marked by cell surface expression of claudin-4 in mouse small intestine., PMID:24603700

Vasostatin-1 antigenic epitope mapping for induction of cellular and humoral immune responses to chromogranin A autoantigen in NOD mice., PMID:24443235

Chromogranin A is a T cell antigen in human type 1 diabetes., PMID:24239002

Scalable in situ hybridization on tissue arrays for validation of novel cancer and tissue-specific biomarkers., PMID:22412953

Targeting protein kinase C by Enzastaurin restrains proliferation and secretion in human pancreatic endocrine tumors., PMID:21606156

Chromogranin/secretogranin proteins in murine heart: myocardial production of chromogranin A fragment catestatin (Chga(364-384))., PMID:21052719

Catestatin attenuates the effects of intrathecal nicotine and isoproterenol., PMID:19785998

The importance of chromogranin A in the development and function of endocrine pancreas., PMID:18722481

Multiple minute nests of incidentally detected paraganglionic cells associated with urothelial carcinoma of the urinary bladder in a 73-year-old woman., PMID:18470683

Elevated plasma chromogranin A levels attributable to assay interference: a source of diagnostic confusion., PMID:16939951

Neuroendocrine modulation induced by selective blockade of TNF-alpha in rheumatoid arthritis., PMID:16855170

Insulin-like growth factor-1 increases intracellular calcium concentration in human primary neuroendocrine pancreatic tumor cells and a pancreatic neuroendocrine tumor cell line (BON-1) via R-type Ca2+ channels and regulates chromogranin a secretion in BON-1 cells., PMID:16424676

Differential expression and processing of chromogranin A and secretogranin II in relation to the secretory status of endocrine cells., PMID:16357044

Measurement of plasma chromogranin A concentrations for assessment of stress responses in dogs with insulin-induced hypoglycemia., PMID:16273918

Comparison between two methods in the determination of circulating chromogranin A in neuroendocrine tumors (NETs): results of a prospective multicenter observational study., PMID:16240843

An immunohistochemical study of chromogranin A and Sp-1 immunoreactive cells in the gastrointestinal tract of ovariectomized rats., PMID:16131820

Expression of amino acid sequences of the chromogranin A molecule and synaptic vesicle protein 2 in neuroendocrine tumors of the lung., PMID:15906087

High plasma levels of human chromogranin A and adrenomedullin in patients with pheochromocytoma., PMID:15850005

Accuracy and clinical correlates of two different methods for chromogranin A assay in neuroendocrine tumors., PMID:15646836

Clinical significance of elevated serum chromogranin A levels., PMID:15513336

Selective reduction of chromogranin A-like immunoreactivities in the prefrontal cortex of schizophrenic subjects: a postmortem study., PMID:15337252

A panel of 11 region-specific radioimmunoassays for measurements of human chromogranin A., PMID:14749043

Chromogranin A protects vessels against tumor necrosis factor alpha-induced vascular leakage., PMID:14734634

Chromogranin A as serum marker of pituitary adenomas., PMID:14616890

Modulation of prostate carcinoma cell growth and apoptosis by chromogranin A., PMID:14532847

[Clinical significant of serum chromogranin A levels for diagnosing pheochromocytoma in hypertensive patients]., PMID:12945223

Chromogranin a processing in human pituitary adenomas and carcinomas: analysis with region-specific antibodies., PMID:12746561

A comparison between three commercial kits for chromogranin A measurements., PMID:12740022

Neuroendocrine differentiation in carcinoma of the breast. Tyramide signal amplification discloses chromogranin A-positive tumour cells in more breast tumours than previously realized., PMID:12529020

Datasheet

Document Download

Anti-CHGA Antibody (R3C21).pdf

 

$ 220
Product specifications
50 μg 220 100 μg 350

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Anti-CHGA Antibody (R3C21) [RHC82706]
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