Catalog No.
RHC29402
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
ELISA: 1:10000, FCM: 1:200-1:400
Target
TSP, THBS1, TSP1, Thrombospondin-1, Glycoprotein G
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P07996
Applications
ELISA, FCM
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3A50
TSP-1-CD47-integrin α4β1 axis drives T cell infiltration and synovial inflammation in rheumatoid arthritis., PMID:40308591
Blockade of TSP-1/CD47 signal axis promotes donor hematopoietic engraftment by improving SEC/MK niche function., PMID:40060904
Mesenchymal stem cells from perinatal tissues promote diabetic wound healing via PI3K/AKT activation., PMID:39923118
The Platelet-Specific Gene Signature in the Immunoglobulin G4-Related Disease Transcriptome., PMID:39859144
Epigenetic memory of radiotherapy in dermal fibroblasts impairs wound repair capacity in cancer survivors., PMID:39468077
Molecular and Functional Cargo of Plasma-Derived Exosomes in Patients with Hereditary Hemorrhagic Telangiectasia., PMID:39336917
Differential responses to thrombospondin-1 and PDGF-BB in smooth muscle cells from atherosclerotic coronary arteries and internal thoracic arteries., PMID:38982274
Stromal thrombospondin 1 suppresses angiogenesis in oral submucous fibrosis., PMID:38403794
Complex changes in serum protein levels in COVID-19 convalescents., PMID:38396092
THBS1 promotes angiogenesis and accelerates ESCC malignant progression by the HIF-1/VEGF signaling pathway., PMID:38233982
Improving cancer immunotherapy via co-delivering checkpoint blockade and thrombospondin-1 downregulator., PMID:37655330
Thrombospondin-1, CD47, and SIRPα display cell-specific molecular signatures in human islets and pancreata., PMID:36791324
Upregulated TSP1 and CD47 expression in the lung in nitrofen-induced congenital diaphragmatic hernia., PMID:36528876
Advances in Anti-metabolic Disease Treatments Targeting CD47., PMID:36201266
Case-only design identifies interactions of genetic risk variants at SIGLEC5 and PLG with the lncRNA CTD-2353F22.1 implying the importance of periodontal wound healing for disease aetiology., PMID:36129033
Human IL-17 and TNF-α Additively or Synergistically Regulate the Expression of Proinflammatory Genes, Coagulation-Related Genes, and Tight Junction Genes in Porcine Aortic Endothelial Cells., PMID:35844613
Fasciola hepatica Fatty Acid Binding Protein 1 Modulates T cell Polarization by Promoting Dendritic Cell Thrombospondin-1 Secretion Without Affecting Metabolic Homeostasis in Obese Mice., PMID:35720355
Proteomic analysis of the bone marrow microenvironment in extramedullary multiple myeloma patients., PMID:35037760
MicroRNA-197-3p mediates damage to human coronary artery endothelial cells via targeting TIMP3 in Kawasaki disease., PMID:34351574
Thrombospondin 1 and 2 along with PEDF inhibit angiogenesis and promote lymphangiogenesis in intrahepatic cholangiocarcinoma., PMID:34329660
THBS1 regulates trophoblast fusion through a CD36-dependent inhibition of cAMP, and its upregulation participates in preeclampsia., PMID:33997182
Extensive cytokine analysis in synovial fluid of osteoarthritis patients., PMID:33895075
THBS1/CD47 Modulates the Interaction of γ-Catenin With E-Cadherin and Participates in Epithelial-Mesenchymal Transformation in Lipid Nephrotoxicity., PMID:33681182
Endothelial cells response to neutrophil-derived extracellular vesicles miRNAs in anti-PR3 positive vasculitis., PMID:33527387
Thrombospondin-1/CD47 signaling modulates transmembrane cation conductance, survival, and deformability of human red blood cells., PMID:32948210
The role of thrombospondin-1 in the pathogenesis of antiphospholipid syndrome., PMID:32709480
Imaging-AMARETTO: An Imaging Genomics Software Tool to Interrogate Multiomics Networks for Relevance to Radiography and Histopathology Imaging Biomarkers of Clinical Outcomes., PMID:32383980
Mechanisms of FH Protection Against Neovascular AMD., PMID:32318056
TSP1-CD47-SIRPα signaling facilitates the development of endometriosis by mediating the survival of ectopic endometrium., PMID:32196807
THBS1 Is a Novel Serum Prognostic Factors of Acute Myeloid Leukemia., PMID:32117788
Thrombospondin 1 (THBS1) Promotes Follicular Angiogenesis, Luteinization, and Ovulation in Primates., PMID:31787928
A Targeted Mass Spectrometry Strategy for Developing Proteomic Biomarkers: A Case Study of Epithelial Ovarian Cancer., PMID:31289117
MicroRNA-194 reduces inflammatory response and human dermal microvascular endothelial cells permeability through suppression of TGF-β/SMAD pathway by inhibiting THBS1 in chronic idiopathic urticaria., PMID:31190349
Initiation of fibrosis in the integrin Αvβ6 knockout mice., PMID:30500364
Elimination of donor CD47 protects against vascularized allograft rejection in mice., PMID:30136356
Expression of adhesion and extracellular matrix genes in human blastocysts upon attachment in a 2D co-culture system., PMID:29846687
Platelet microparticle delivered microRNA-Let-7a promotes the angiogenic switch., PMID:29684582
Immune complexome analysis of antigens in circulating immune complexes from patients with acute cellular rejection after living donor liver transplantation., PMID:29477751
Potential role of sirtuin 1 in Müller glial cells in mice choroidal neovascularization., PMID:28886036
Hedgehog signalling pathway orchestrates angiogenesis in triple-negative breast cancers., PMID:28441382
Stabilization of the p53-DNA Complex by the Nuclear Protein Dmp1α., PMID:28406729
TSP1-CD47 signaling is upregulated in clinical pulmonary hypertension and contributes to pulmonary arterial vasculopathy and dysfunction., PMID:27742621
Surface Glycoproteins of Exosomes Shed by Myeloid-Derived Suppressor Cells Contribute to Function., PMID:27728760
Interstitial pneumonia induced by bleomycin treatment is exacerbated in Angptl2-deficient mice., PMID:27542805
CD47 regulates renal tubular epithelial cell self-renewal and proliferation following renal ischemia reperfusion., PMID:27259369
Physiological levels of thrombospondin-1 decrease NO-dependent vasodilation in coronary microvessels from aged rats., PMID:27199114
A function-blocking CD47 antibody suppresses stem cell and EGF signaling in triple-negative breast cancer., PMID:26840086
Molecular profiling of cetuximab and bevacizumab treatment of colorectal tumours reveals perturbations in metabolic and hypoxic response pathways., PMID:26517691
Fresolimumab treatment decreases biomarkers and improves clinical symptoms in systemic sclerosis patients., PMID:26098215
Thrombospondin peptide ABT-898 inhibits inflammation and angiogenesis in a colitis model., PMID:26034351
For research use only. Not for human or drug use.
