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Anti-GPI Antibody (R2Z96)

Catalog #:   RHC21502 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG1
Applications: IF, IHC, WB
Accession: P06744
Overview

Catalog No.

RHC21502

Species reactivity

Human

Host species

Mouse

Isotype

IgG1

Clonality

Monoclonal

Tested applications

IF: 1:200-1:1000, IHC: 1:200-1:1000, WB: 1:500-1:2000

Target

GPI, NLK, Neuroleukin, Phosphohexose isomerase, PHI, Sperm antigen 36, Autocrine motility factor, AMF, SA-36, PGI, Glucose-6-phosphate isomerase, Phosphoglucose isomerase

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P06744

Applications

IF, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R2Z96

Data Image
  • Immunofluorescence
    Confocal Immunofluorescence analysis of L-02 cells using GPI mouse mAb (green). Red: Actin filaments have been labeled with DY-554 phalloidin. Blue: DRAQ5 fluorescent DNA dye.
  • Immunohistochemical
    Immunohistochemical analysis of paraffin-embedded human Kidney tissues using GPI mouse mAb.
  • Western blot
    Western blot analysis using GPI mouse mAb against HepG2 (1) , SMMC-7721 (2) cell lysate and rat liver tissues lysate (3).
References

Versatile tethering system to control cell-specific targeting of bioengineered extracellular vesicles., PMID:40461587

Platform-based BST-2-targeted microbubbles enhance HIFU therapy and effectively inhibit prostate cancer residual growth., PMID:40436774

Infection with the Endonuclear Symbiotic Bacterium Holospora obtusa Reversibly Alters Surface Antigen Expression of the Host Paramecium caudatum., PMID:40431163

Animal Models in Rheumatoid Arthritis: Is There a Correlation Between Autoantibodies in Human Pathology and Animal Models?, PMID:40427650

Diagnostic value of blood coagulation index in obstetric antiphospholipid syndrome and its subtypes., PMID:40409231

Targeted CD47 checkpoint blockade using a mesothelin-directed antibody construct for enhanced solid tumor-specific immunotherapy., PMID:40402266

Itolizumab regulates activating and inhibitory signals on effector cells, improving their cytotoxicity against CD318+ tumor cell lines., PMID:40391211

Multicenter study to improve clinical interpretation of anticardiolipin and anti-β2-glycoprotein I antibody test results for diagnosis of antiphospholipid syndrome., PMID:40383153

[Preliminary study of mesothelin-loaded paclitaxel nanoparticles for ultrasound molecular imaging and treatment of ovarian cancer]., PMID:40375590

Molecular Mechanisms of Tumor Progression and Novel Therapeutic and Diagnostic Strategies in Mesothelioma., PMID:40362535

Detection of S1 spike protein in CD16+ monocytes up to 245 days in SARS-CoV-2-negative post-COVID-19 vaccine syndrome (PCVS) individuals., PMID:40358138

Structural and Functional Characterization of the 28 kDa Structured Core of BmSA1, the Major Surface Antigen of Babesia Microti., PMID:40345974

Virus-induced RGMa expression drives neurodegeneration in HTLV-1-associated myelopathy., PMID:40305434

Advancing pancreatic cancer therapy by mesothelin-specific nanobody conjugation., PMID:40275270

Evaluating therapeutic plasma exchange and protease inhibitors as mechanisms to reduce soluble mesothelin., PMID:40240561

Adenosine-generating CD39+ plasmablasts predispose to successful infliximab therapy in pediatric IBD., PMID:40199584

Affinity enrichment of placental extracellular vesicles from minimally processed maternal plasma with magnetic nanowires., PMID:40172922

Distribution of HLA-DRB1 Alleles in Patients With Antiphospholipid Syndrome and Their Association With Antiphospholipid Antibodies Presence and Damage Indexes., PMID:40165867

A high-affinity antibody-drug conjugates Actuximab-MMAE for potent and selective targeting of CEACAM5-Positive tumors., PMID:40158720

Enhancing activity of FcαRI-bispecific antibodies using glycoengineering., PMID:40156381

New World Primates and Their Human Counterparts Share Diseases That Abound with CEACAM and Other Effector Molecules., PMID:40141825

23ME-01473, an Fc Effector-Enhanced Anti-ULBP6/2/5 Antibody, Restores NK Cell-Mediated Antitumor Immunity through NKG2D and FcγRIIIa Activation., PMID:40116579

Crovalimab: a new era in paroxysmal nocturnal hemoglobinuria management., PMID:40110253

Development of CD73 Inhibitors in Tumor Immunotherapy and Opportunities in Imaging and Combination Therapy., PMID:40106690

Potent and durable control of mesothelin-expressing tumors by a novel T cell-secreted bi-specific engager., PMID:40081946

Novel anti-CD73-IL-2v bispecific fusion protein augments antitumor immunity by alleviating immunosuppressive adenosine pathways in CD8+ T cells., PMID:40081940

β-Amyloid Induces Microglial Expression of GPC4 and APOE Leading to Increased Neuronal Tau Pathology and Toxicity., PMID:40060520

BTK inhibitors enhance NKG2D ligand expression by regulating IL-10/STAT3 pathway in activated non-GCB diffuse large B-cell lymphoma cells., PMID:40029697

Expression of Glycoprotein 2 and Its Glycosylation in Human Cowper's Gland., PMID:40026103

Efficacy of natural killer T and gammadelta T cells in mesothelin-targeted immunotherapy of pancreatic cancer., PMID:39995672

Inhibition of repulsive guidance molecule A ameliorates diabetes-induced cognitive decline and hippocampal neurogenesis impairment in mice., PMID:39972167

Fc gamma receptors activate different protein kinase C isoforms in human neutrophils., PMID:39946245

Antiphospholipid Syndrome: A Comprehensive Clinical Review., PMID:39941405

BNT162b2 COVID-19 vaccination elicits the expansion of CD16+CD8+ T cells endowed with natural killer cell features., PMID:39894227

CD16 and CD57 expressing gamma delta T cells in acute HIV-1 infection are associated with the development of neutralization breadth., PMID:39888945

Targeting Mesothelin Enhances Personalized Neoantigen Vaccine Induced Antitumor Immune Response in Orthotopic Pancreatic Cancer Mouse Models., PMID:39887656

Influence of plasma exosomes from women living with HIV Stratified by HAND on monocyte subpopulations from healthy women without HIV., PMID:39885101

Blocking the CD39/CD73 pathway synergizes with anti-CD20 bispecific antibody in nodal B-cell lymphoma., PMID:39884778

Development of a novel molecular probe for visualizing mesothelin on the tumor via positron emission tomography., PMID:39878895

Cripto-1 acts as a molecular bridge linking nodal to ALK4 via distinct structural domains., PMID:39840816

Randomized Phase II Study of Bevacizumab with Weekly Anetumab Ravtansine or Weekly Paclitaxel in Platinum-Resistant/Refractory High-Grade Ovarian Cancer (NCI Trial)., PMID:39836408

Broad-Spectrum Efficacy of CEACAM6-Targeted Antibody-Drug Conjugate with BET Protein Degrader in Colorectal, Lung, and Breast Cancer Mouse Models., PMID:39812376

Immune complexes-mediated activation of neutrophils in systemic lupus erythematosus is dependent on RNA recognition by toll-like receptor 8., PMID:39776899

The Nonclinical Safety Assessment of a Novel Anti-CEACAM5 Antibody Exatecan Conjugate Predicts a Low Risk for Interstitial Lung Disease (ILD) in Patients-The Putative Mechanism Behind ILD., PMID:39754485

Inhibiting Tyrosine Kinase 2 Ameliorates Antiphospholipid Syndrome Nephropathy., PMID:39742289

An antibody cocktail targeting two different CD73 epitopes enhances enzyme inhibition and tumor control., PMID:39738003

Label-free electrochemical assessment of human serum and cancer cells to determine the folate receptor cancer biomarker., PMID:39729969

Interpreting high levels of unfolded Von Willebrand Factor in patients with the antiphospholipid syndrome., PMID:39726607

Bone marrow stromal cell antigen 2 is broadly expressed in the different pluripotent states of human pluripotent stem cells and regulates the expression of pluripotency genes and three germ layer markers., PMID:39718725

IgLON5 autoimmunity secondary to immune checkpoint inhibitor., PMID:39709726

Datasheet

Document Download

Anti-GPI Antibody (R2Z96).pdf

 

$ 220
Product specifications
50 μg 220 100 μg 350

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Anti-GPI Antibody (R2Z96) [RHC21502]
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