Catalog No.
RHC19911
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
ELISA: 1:10000, FCM: 1:200-1:400, WB: 1:500-1:2000
Target
pRb, p110-RB1, Retinoblastoma-associated protein, Rb, p105-Rb, RB1, pp110
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P06400
Applications
ELISA, FCM, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R2Z65
Exceptional Long-term Response to Immunotherapy in an African American Man With STK11/TP53/RB1-Mutated Metastatic Lung Adenocarcinoma., PMID:40448514
Infection with the Endonuclear Symbiotic Bacterium Holospora obtusa Reversibly Alters Surface Antigen Expression of the Host Paramecium caudatum., PMID:40431163
Current and future therapies for small cell lung carcinoma., PMID:40170056
Induction chemotherapy followed by camrelizumab plus apatinib and chemotherapy as first-line treatment for extensive-stage small-cell lung cancer: a multicenter, single-arm trial., PMID:39962074
Enigmatic intractable Epilepsy patients have antibodies that bind glutamate receptor peptides, kill neurons, damage the brain, and cause Generalized Tonic Clonic Seizures., PMID:39932550
Unusual Presentation of Advanced Urothelial Cancer in a Young Patient., PMID:39890191
Anti-Idiotypic Antibody as a Booster Vaccine Against Respiratory Syncytial Virus., PMID:39852814
The Impact of Genetic Mutations on the Efficacy of Immunotherapies in Lung Cancer., PMID:39596025
FGFR Inhibitors in Urothelial Cancer: From Scientific Rationale to Clinical Development., PMID:39536791
Comprehensive Genomic Assessment of Advanced-Stage GI Stromal Tumors Using the Japanese National Center for Cancer Genomics and Advanced Therapeutics Database., PMID:39447098
Adebrelimab plus chemotherapy and sequential thoracic radiotherapy as first-line therapy for extensive-stage small-cell lung cancer (ES-SCLC): a phase II trial., PMID:39252865
Emerging advances in defining the molecular and therapeutic landscape of small-cell lung cancer., PMID:38965396
PD-L1 and nectin-4 expression and genomic characterization of bladder cancer with divergent differentiation., PMID:38959291
A Modular Trial of Androgen Signaling Inhibitor Combinations Testing a Risk-Adapted Strategy in Patients with Metastatic Castration-Resistant Prostate Cancer., PMID:38683200
Therapeutic Advances and Challenges for the Management of HPV-Associated Oropharyngeal Cancer., PMID:38612819
Glioblastoma Therapy: Past, Present and Future., PMID:38473776
Pan-cancer Genomic Analysis of AXL Mutations Reveals a Novel, Recurrent, Functionally Activating AXL W451C Alteration Specific to Myxofibrosarcoma., PMID:38369783
Treatment-related Neuroendocrine Prostate Carcinoma-Diagnostic and Molecular Correlates., PMID:38223983
Targeting DNA methylation and B7-H3 in RB1-deficient and neuroendocrine prostate cancer., PMID:37967200
Ginsenoside Rb1 enhanced immunity and altered the gut microflora in mice immunized by H1N1 influenza vaccine., PMID:37868069
Survey of NF1 inactivation by surrogate immunohistochemistry in ovarian carcinomas., PMID:37820398
Gemcitabine and cisplatin plus nivolumab as organ-sparing treatment for muscle-invasive bladder cancer: a phase 2 trial., PMID:37783966
Tumor-derived biomarkers predict efficacy of B7H3 antibody-drug conjugate treatment in metastatic prostate cancer models., PMID:37725435
Biomarkers-Based Cost-Effectiveness of Toripalimab Plus Chemotherapy for Patients with Treatment-Naive Advanced Non-Small Cell Lung Cancer., PMID:37715852
A Fluorescent Probe as a Lead Compound for a Selective α-Synuclein PET Tracer: Development of a Library of 2-Styrylbenzothiazoles and Biological Evaluation of [18F]PFSB and [18F]MFSB., PMID:37663501
[Fibrocartilaginous lipoma: a clinicopathological analysis of six cases]., PMID:37527988
Emerging roles of Aurora-A kinase in cancer therapy resistance., PMID:37521867
Ginsenosides in cancer: Targeting cell cycle arrest and apoptosis., PMID:37451663
Genomic analysis of plasma circulating tumor DNA in patients with heavily pretreated HER2 + metastatic breast cancer., PMID:37336919
Clinical insights into small cell lung cancer: Tumor heterogeneity, diagnosis, therapy, and future directions., PMID:37329269
Diagnostic Utility of TSSC3 and RB1 Immunohistochemistry in Hydatidiform Mole., PMID:37298606
Genetic mutations in HER2-positive breast cancer: possible association with response to trastuzumab therapy., PMID:37202799
PROTACs in the Management of Prostate Cancer., PMID:37175108
The efficacy and adverse effects of nivolumab and lenvatinib in the treatment of advanced hepatocellular carcinoma., PMID:37114307
Loss of Rb1 Associated With the Onset of Acquired Resistance to Trastuzumab Deruxtecan in TP53-/HER2-Mutated Non-Small-Cell Lung Cancer: Case Series., PMID:36809053
Modified method for differentiation of myeloid-derived suppressor cells in vitro enhances immunosuppressive ability via glutathione metabolism., PMID:36605123
Understanding the killer-cell immunoglobulin like receptor polymorphism in retinoblastoma., PMID:36594723
LATE CHOROIDAL NEOVASCULAR COMPLICATIONS IN A PATIENT TREATED FOR RETINOBLASTOMA. A CASE REPORT., PMID:36543599
Phosphohistidine signaling promotes FAK-RB1 interaction and growth factor-independent proliferation of esophageal squamous cell carcinoma., PMID:36513743
Immune Checkpoint Blockade Outcome in Small-Cell Lung Cancer and Its Relationship With Retinoblastoma Mutation Status and Function., PMID:36044718
Heterogeneity of resistant mechanisms in an EGFR-TKI relapsed patient with EGFR amplification and response to nimotuzumab: A case report., PMID:36033496
Upregulation of adiponectin by Ginsenoside Rb1 contributes to amelioration of hepatic steatosis induced by high fat diet., PMID:35818425
The EEF1AKMT3/MAP2K7/TP53 axis suppresses tumor invasiveness and metastasis in gastric cancer., PMID:35753528
Immunohistochemical Assays for Bladder Cancer Molecular Subtyping: Optimizing Parsimony and Performance of Lund Taxonomy Classifiers., PMID:35437049
Phase I, multicenter, open-label study of intravenous VCN-01 oncolytic adenovirus with or without nab-paclitaxel plus gemcitabine in patients with advanced solid tumors., PMID:35338084
Association of Anti-EGFR Antibody and MEK Inhibitor in Gynecological Cancer Harboring RAS Mutation: A Case Series., PMID:35328764
VCN-01 disrupts pancreatic cancer stroma and exerts antitumor effects., PMID:35149591
[Immunoglobulin M multiple myeloma: a six-case report and literature review]., PMID:35045672
Ginsenoside Rb1 Lessens Gastric Precancerous Lesions by Interfering With β-Catenin/TCF4 Interaction., PMID:34594214
Metastatic Castration-Resistant Prostate Cancer Remains Dependent on Oncogenic Drivers Found in Primary Tumors., PMID:34568716
For research use only. Not for human or drug use.
