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Anti-GSN Antibody (R2Z62)

Catalog #:   RHC19807 Specific References (42) DATASHEET
Host species: Mouse
Isotype: IgG1
Applications: ELISA, FCM, IHC
Accession: P06396
Overview

Catalog No.

RHC19807

Species reactivity

Human

Host species

Mouse

Isotype

IgG1

Clonality

Monoclonal

Tested applications

ELISA: 1:10000, FCM: 1:200-1:400, IHC: 1:200-1:1000

Target

Gelsolin, Brevin, GSN, ADF, AGEL, Actin-depolymerizing factor

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P06396

Applications

ELISA, FCM, IHC

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R2Z62

Data Image
  • Flow Cytometry
    Flow cytometric analysis of Jurkat cells using GSN mouse mAb (green) and negative control (red).
  • Flow Cytometry
    Flow cytometric analysis of THP-1 cells using GSN mouse mAb (green) and negative control (red).
  • Immunohistochemical
    Immunohistochemical analysis of paraffin-embedded human esophageal cancer tissues using GSN mouse mAb with DAB staining.
  • Immunohistochemical
    Immunohistochemical analysis of paraffin-embedded human rectal cancer tissues using GSN mouse mAb with DAB staining.
References

Phase II study of venetoclax added to bendamustine and obinutuzumab in patients with high-risk follicular lymphoma as front-line therapy: PrE0403., PMID:40355425

Global patterns of amyloid typing: results of a survey by the International Society of Amyloidosis (ISA)., PMID:39928315

Rubella virus seropositivity after infection or vaccination as a risk factor for multiple sclerosis., PMID:39023088

The Alzheimer's disease-linked protease BACE2 cleaves VEGFR3 and modulates its signaling., PMID:38888964

Overall survival of patients with cHL who progress after autologous stem cell transplant: results in the novel agent era., PMID:37729621

Targeting the glycine-rich domain of TDP-43 with antibodies prevents its aggregation in vitro and reduces neurofilament levels in vivo., PMID:37434215

Whole-body cellular mapping in mouse using standard IgG antibodies., PMID:37430076

Safety and efficacy of tafasitamab with or without lenalidomide added to first-line R-CHOP for DLBCL: the phase 1b First-MIND study., PMID:37369099

High-grade B-cell lymphoma, not otherwise specified: a multi-institutional retrospective study., PMID:37171397

Integrated analysis of circulating and tissue proteomes reveals that fibronectin 1 is a potential biomarker in papillary thyroid cancer., PMID:37158852

Orally Bioavailable Macrocyclic Peptide That Inhibits Binding of PCSK9 to the Low Density Lipoprotein Receptor., PMID:37125593

SAR443809: a selective inhibitor of the complement alternative pathway, targeting complement factor Bb., PMID:36897252

Increased FOXJ1 protein expression is associated with improved overall survival in high-grade serous ovarian carcinoma: an Ovarian Tumor Tissue Analysis Consortium Study., PMID:36323878

Drug Release from Gelsolin-Targeted Phase-Transition Nanoparticles Triggered by Low-Intensity Focused Ultrasound., PMID:35023919

Efficacy of front-line immunochemotherapy for follicular lymphoma: a network meta-analysis of randomized controlled trials., PMID:34987165

Discovery of plasma biomarkers with data-independent acquisition mass spectrometry and antibody microarray for diagnosis and risk stratification of pulmonary embolism., PMID:33825327

Clinical manifestations of, diagnostic approach to, and treatment of neurolymphomatosis in the rituximab era., PMID:33661298

[Effect of ultrasound contrast agent targeting gelatin on uptake of mouse ascites hepatocellular carcinoma cell lines with high lymphatic metastasis]., PMID:32375448

Cell-to-cell transmission of C9orf72 poly-(Gly-Ala) triggers key features of ALS/FTD., PMID:32175624

Cellular and Molecular Probing of Intact Human Organs., PMID:32059778

Leveraging gene expression subgroups to classify DLBCL patients and select for clinical benefit from a novel agent., PMID:31977005

Deep Learning Reveals Cancer Metastasis and Therapeutic Antibody Targeting in the Entire Body., PMID:31835038

Potassium channels in omnipause neurons., PMID:31325972

Complex inter-relationship of body mass index, gender and serum creatinine on survival: exploring the obesity paradox in melanoma patients treated with checkpoint inhibition., PMID:30922394

Human SPG11 cerebral organoids reveal cortical neurogenesis impairment., PMID:30476097

Immunohistochemical characteristics of neurons in the ganglia of the greater splanchnic nerve of the pig., PMID:29297566

Beyond RCHOP: A Blueprint for Diffuse Large B Cell Lymphoma Research., PMID:27986884

Non-Invasive Imaging of Amyloid Deposits in a Mouse Model of AGel Using 99mTc-Modified Nanobodies and SPECT/CT., PMID:27130233

Expression of Cytoplasmic Gelsolin in Rat Brain After Experimental Subarachnoid Hemorrhage., PMID:25744577

Gestational diabetes mellitus impairs fetal endothelial cell functions through a mechanism involving microRNA-101 and histone methyltransferase enhancer of zester homolog-2., PMID:25614281

An ER-directed gelsolin nanobody targets the first step in amyloid formation in a gelsolin amyloidosis mouse model., PMID:25601851

Chaperone nanobodies protect gelsolin against MT1-MMP degradation and alleviate amyloid burden in the gelsolin amyloidosis mouse model., PMID:25023329

Gelsolin levels are decreased in ankylosing spondylitis patients undergoing anti-TNF-alpha therapy., PMID:24351434

Mass spectrometric-based proteomic analysis of amyloid neuropathy type in nerve tissue., PMID:20937937

[Study on proteomic specificity of unstable angina with qi deficiency and blood stasis syndrome]., PMID:19702077

A large-scale rheumatoid arthritis genetic study identifies association at chromosome 9q33.2., PMID:18648537

Anti-apoptotic function of gelsolin in fas antibody-induced liver failure in vivo., PMID:16507893

Gelsolin mediates collagen phagocytosis through a rac-dependent step., PMID:14617805

Selective inhibition of IgG-mediated phagocytosis in gelsolin-deficient murine neutrophils., PMID:10946270

Delayed retraction of filopodia in gelsolin null mice., PMID:9298983

Retroviral synthetic peptide serum antibodies in human sporadic amyotrophic lateral sclerosis., PMID:8008625

[Comparative study of the effectiveness of the interferon inducers, poly(I) : poly(C) and GSS (gossypol-beta-aminoethylsodium sulfate), in combination with a specific vaccine in experimental infection with the human acute encephalomyelitis virus]., PMID:7434726

Datasheet

Document Download

Anti-GSN Antibody (R2Z62).pdf

 

$ 220
Product specifications
50 μg 220 100 μg 350

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Anti-GSN Antibody (R2Z62) [RHC19807]
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