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Anti-TFAP2A Antibody (R2Z31)

Catalog #:   RHC17505 Specific References (21) DATASHEET
Host species: Mouse
Isotype: IgG1
Applications: ELISA, FCM, IF
Accession: P05549
Overview

Catalog No.

RHC17505

Species reactivity

Human

Host species

Mouse

Isotype

IgG1

Clonality

Monoclonal

Tested applications

ELISA: 1:10000, FCM: 1:200-1:400, IF: 1:200-1:1000

Target

Transcription factor AP-2-alpha, AP-2 transcription factor, Activating enhancer-binding protein 2-alpha, TFAP2A, AP2-alpha, AP-2, Activator protein 2, TFAP2, AP2TF

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P05549

Applications

ELISA, FCM, IF

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R2Z31

Data Image
  • Flow Cytometry
    Flow cytometric analysis of Hela cells using TFAP2A mouse mAb (green) and negative control (red).
  • Immunofluorescence
    Immunofluorescence analysis of Hela cells using TFAP2A mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
References

Tyrosine phosphorylation-mediated YAP1-TFAP2A interactions coordinate transcription and trastuzumab resistance in HER2+ breast cancer., PMID:38219531

Epigenetically modified AP-2α by DNA methyltransferase facilitates glioma immune evasion by upregulating PD-L1 expression., PMID:37330579

Integrated single-cell and bulk gene expression and ATAC-seq reveals heterogeneity and early changes in pathways associated with resistance to cetuximab in HNSCC-sensitive cell lines., PMID:32362655

Robust induction of neural crest cells to derive peripheral sensory neurons from human induced pluripotent stem cells., PMID:32152328

Heterodimerization of TFAP2 pioneer factors drives epigenomic remodeling during neural crest specification., PMID:31848212

Tissue organization alters gene expression in equine induced trophectoderm cells., PMID:28161437

Ascorbic acid uptaken by sodium-dependent vitamin C transporter 2 induces βhCG expression through Sp1 and TFAP2A transcription factors in human choriocarcinoma cells., PMID:22745243

Alternative TFAP2A isoforms have distinct activities in breast cancer., PMID:21375726

AP2 transcription factor induces apoptosis in retinoblastoma cells., PMID:20607706

AP-2alpha knockout mice exhibit optic cup patterning defects and failure of optic stalk morphogenesis., PMID:20150232

Expression patterns of the transcription factor AP-2alpha during hair follicle morphogenesis and cycling., PMID:12839558

Pituitary tumor AP-2alpha recognizes a cryptic promoter in intron 4 of fibroblast growth factor receptor 4., PMID:12642581

Transcription of cholesterol side-chain cleavage cytochrome P450 in the placenta: activating protein-2 assumes the role of steroidogenic factor-1 by binding to an overlapping promoter element., PMID:12145340

Ap-2 and Ikaros regulate transcription of human placental leucine aminopeptidase/oxytocinase gene., PMID:11798181

Activator protein 2alpha transcription factor expression is associated with luminal differentiation and is lost in prostate cancer., PMID:11751506

Expression pattern of AP-2 transcription factors in cervical cancer cells and analysis of their influence on human papillomavirus oncogene transcription., PMID:11485026

Expression of transcription factor AP-2alpha predicts survival in epithelial ovarian cancer., PMID:10864206

Immunohistochemical analysis reveals a tumour suppressor-like role for the transcription factor AP-2 in invasive breast cancer., PMID:10629551

Keratin 10 gene expression during differentiation of mouse epidermis requires transcription factors C/EBP and AP-2., PMID:10588870

Differential expression of AP-2alpha and AP-2beta in the developing chick retina: repression of R-FABP promoter activity by AP-2., PMID:10090146

Tissue-specific in vivo protein-DNA interactions at the promoter region of the Xenopus 63 kDa keratin gene during metamorphosis., PMID:7501476

Datasheet

Document Download

Anti-TFAP2A Antibody (R2Z31).pdf

 

$ 220
Product specifications
50 μg 220 100 μg 350

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Anti-TFAP2A Antibody (R2Z31) [RHC17505]
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