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Anti-EDN1 Antibody (R2Z18)

Catalog #:   RHC15902 Specific References (20) DATASHEET
Host species: Mouse
Isotype: IgG2a
Applications: ELISA, FCM, IF
Accession: P05305
Overview

Catalog No.

RHC15902

Species reactivity

Human, Mouse

Host species

Mouse

Isotype

IgG2a

Clonality

Monoclonal

Tested applications

ELISA: 1:10000, FCM: 1:200-1:400, IF: 1:200-1:1000

Target

Endothelin-1, EDN1, PPET1, ET-1, Preproendothelin-1

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P05305

Applications

ELISA, FCM, IF

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R2Z18

Data Image
  • Flow Cytometry
    Flow cytometric analysis of Hela cells using EDN1 mouse mAb (green) and negative control (red).
  • Flow Cytometry
    Flow cytometric analysis of HepG2 cells using EDN1 mouse mAb (green) and negative control (red).
  • Flow Cytometry
    Flow cytometric analysis of NIH3T3 cells using EDN1 mouse mAb (green) and negative control (red).
  • Immunofluorescence
    Immunofluorescence analysis of Hela cells using EDN1 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
References

VEPTP inhibition with an extracellular domain targeting antibody did not restore albuminuria in a mouse model of diabetic kidney disease., PMID:39324545

Comprehensive analysis of the endothelin system in the kidneys of mice, rats, and humans., PMID:38904098

Pharmacogenomics of intravenous immunoglobulin response in Kawasaki disease., PMID:38259468

Targeting IL-11 system as a treatment of pulmonary arterial hypertension., PMID:37949331

Effects of Cyclosporine A and Adalimumab on the expression profiles histaminergic system-associated genes and microRNAs regulating these genes in HaCaT cells., PMID:35899934

The Influence of Adalimumab and Cyclosporine A on the Expression Profile of the Genes Related to TGFβ Signaling Pathways in Keratinocyte Cells Treated with Lipopolysaccharide A., PMID:32774143

Identification of NFAT5 as a transcriptional regulator of the EDN1 gene in collecting duct., PMID:30623723

Intercellular Genetic Interaction Between Irf6 and Twist1 during Craniofacial Development., PMID:28769044

Cardiac fibroblast transcriptome analyses support a role for interferogenic, profibrotic, and inflammatory genes in anti-SSA/Ro-associated congenital heart block., PMID:28626076

Endothelin-1 genetic polymorphism as predictive marker for bevacizumab in metastatic breast cancer., PMID:27139155

MicroRNA regulation of endothelin-1 mRNA in renal collecting duct cells., PMID:24632479

Polymorphisms of endothelin 1 (G5665T and T-1370G) and endothelin receptor type A (C+70G and G-231A) in Graves' disease., PMID:24291390

The fate of renal allografts hinges on responses of the microvascular endothelium., PMID:22710034

Endothelin-1 is elevated in Alzheimer's disease and upregulated by amyloid-β., PMID:22330820

MTHFR and MSX1 contribute to the risk of nonsyndromic cleft lip/palate., PMID:20572854

Endothelin-1, endothelin converting enzyme-1 and endothelin receptors in the porcine corpus luteum., PMID:19783117

Transcriptome analyses in normal prostate epithelial cells exposed to low-dose cadmium: oncogenic and immunomodulations involving the action of tumor necrosis factor., PMID:18560533

Endothelin axis polymorphisms in patients with scleroderma., PMID:16947775

Variants of endothelin-1 and its receptors in atopic asthma., PMID:10448102

Aortic arch malformations and ventricular septal defect in mice deficient in endothelin-1., PMID:7615798

Datasheet

Document Download

Anti-EDN1 Antibody (R2Z18).pdf

 

$ 220
Product specifications
50 μg 220 100 μg 350

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Anti-EDN1 Antibody (R2Z18) [RHC15902]
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