Anti-LGALS2 Antibody (R2Z10)

Catalog No.

RHC14701

Species reactivity

Human

Host species

Mouse

Isotype

IgG1

Clonality

Monoclonal

Tested applications

IHC: 1:100-1:200, IP: 1:100-1:200, WB: 1:500-1:1000

Target

HL14, Galectin-2, Lactose-binding lectin 2, S-Lac lectin 2, Beta-galactoside-binding lectin L-14-II, LGALS2, Gal-2

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P05162

Applications

IHC, IP, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R2Z10

Evaluation of potential antiviral activities of antimicrobial peptides in fish mucus., PMID:38378226

In vivo multidimensional CRISPR screens identify Lgals2 as an immunotherapy target in triple-negative breast cancer., PMID:35767614

Anti-Galectin-2 Antibody Treatment Reduces Atherosclerotic Plaque Size and Alters Macrophage Polarity., PMID:34852377

Galectin-lattice sustains function of cationic amino acid transporter and insulin secretion of pancreatic β cells., PMID:31960919

Brugia malayi galectin 2 is a tandem-repeat type galectin capable of binding mammalian polysaccharides., PMID:31738955

Development of an immunochromatographic device to detect antibodies for rapid diagnosis of human angiostrongyliasis., PMID:31690362

Stimulation of Collateral Vessel Growth by Inhibition of Galectin 2 in Mice Using a Single-Domain Llama-Derived Antibody., PMID:31594443

Application of Recombinant Angiostrongylus cantonensis Galectin-2 Protein for Serodiagnosis of Human Angiostrongyliasis by Immunoblotting., PMID:31392957

Galectin-2 suppresses nematode development by binding to the invertebrate-specific galactoseβ1-4fucose glyco-epitope., PMID:30874734

Placental Expression Patterns of Galectin-1, Galectin-2, Galectin-3 and Galectin-13 in Cases of Intrauterine Growth Restriction (IUGR)., PMID:27070577

Immunohistochemical Studies on Galectin Expression in Colectomised Patients with Ulcerative Colitis., PMID:26885508

Galectin-2 induces a proinflammatory, anti-arteriogenic phenotype in monocytes and macrophages., PMID:25884209

Methodologies for measurement of cardiac markers., PMID:24507795

The involvement of CD146 and its novel ligand Galectin-1 in apoptotic regulation of endothelial cells., PMID:23223580

Autoantibodies against galectins are associated with antiphospholipid syndrome in patients with systemic lupus erythematosus., PMID:22887862

Autoantibodies against galectin-2 peptides as biomarkers for the antiphospholipid syndrome., PMID:22635232

Open Wound Healing In Vivo: Monitoring Binding and Presence of Adhesion/Growth-Regulatory Galectins in Rat Skin during the Course of Complete Re-Epithelialization., PMID:22096259

Serum galectin-2, -4, and -8 are greatly increased in colon and breast cancer patients and promote cancer cell adhesion to blood vascular endothelium., PMID:21933892

Antibody-based proteomics for discovery and exploration of proteins expressed in pancreatic islets., PMID:20587347

Galectin-2 at the enterocyte brush border of the small intestine., PMID:19657968

Immunohistochemical localization of six galectin subtypes in the mouse digestive tract., PMID:18796404

Human galectin-2: nuclear presence in vitro and its modulation by quiescence/stress factors., PMID:17999373

Gene-expression signature of adhesion/growth-regulatory tissue lectins (galectins) in transitional cell cancer and its prognostic relevance., PMID:17927590

Prototype chicken galectins revisited: characterization of a third protein with distinctive hydrodynamic behaviour and expression pattern in organs of adult animals., PMID:17887955

Co-expression and functional interaction of silicatein with galectin: matrix-guided formation of siliceous spicules in the marine demosponge Suberites domuncula., PMID:16495220

Human galectin-2: expression profiling by RT-PCR/immunohistochemistry and its introduction as a histochemical tool for ligand localization., PMID:16136502

Prognostic significance of endogenous adhesion/growth-regulatory lectins in lung cancer., PMID:16127288

Upregulation of galectins-1 and -3 in human colon cancer and their role in regulating cell migration., PMID:12471620

Production and characterization of a monoclonal antibody able to discriminate galectin-1 from galectin-2 and galectin-3., PMID:9597540

Identification of different galectins by immunoblotting after two-dimensional polyacrylamide get electrophoresis with immobilized pH gradients., PMID:8740185

Isolation and expression of a gene encoding L-14-II, a new human soluble lactose-binding lectin., PMID:1375225

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