Catalog No.
RHC11601
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
WB: 1:500-1:1000
Target
IFNW1, Interferon alpha-II-1, Interferon omega-1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P05000
Applications
WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R2Y90
Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths., PMID:34413139
Multiplex Autoantibody Detection in Patients with Autoimmune Polyglandular Syndromes., PMID:34071130
Mild COVID-19 despite autoantibodies against type I IFNs in autoimmune polyendocrine syndrome type 1., PMID:34061776
Autoimmune polyendocrine syndrome type 1: an Italian survey on 158 patients., PMID:34003463
Severe COVID-19 in an APS1 patient with interferon autoantibodies treated with plasmapheresis., PMID:33892926
Vasculitis as a Major Morbidity Factor in Patients With Partial RAG Deficiency., PMID:33193364
Autoantibodies against type I IFNs in patients with life-threatening COVID-19., PMID:32972996
Antiviral Effects of Hydroxychloroquine and Type I Interferon on In Vitro Fatal Feline Coronavirus Infection., PMID:32456286
Egyptian Rousette IFN-ω Subtypes Elicit Distinct Antiviral Effects and Transcriptional Responses in Conspecific Cells., PMID:32231668
The heterogeneity of autoimmune polyendocrine syndrome type 1: Clinical features, new mutations and cytokine autoantibodies in a Brazilian cohort from tertiary care centers., PMID:30287219
HPV11 E6 mutation by overexpression of APOBEC3A and effects of interferon-ω on APOBEC3s and HPV11 E6 expression in HPV11.HaCaT cells., PMID:29100527
Assessment of autoantibodies to interferon-ω in patients with autoimmune polyendocrine syndrome type 1: using a new immunoprecipitation assay., PMID:28099118
Characterization and antivirus activities of a novel bovine IFN-omega24., PMID:25951414
Oral and subcutaneous therapy of canine atopic dermatitis with recombinant feline interferon omega., PMID:24548425
[Preparation and characterization of mono PEGylated recombinant human interferon omega]., PMID:22645765
Use of recombinant interferon omega in feline retrovirosis: from theory to practice., PMID:21719116
Preparation of CHO cell-derived rhIFN-ω-Fc with improved pharmacokinetics., PMID:21277904
AIRE gene mutations and autoantibodies to interferon omega in patients with chronic hypoparathyroidism without APECED., PMID:20718774
Human plasmacytoid dendritic cell accumulation amplifies their type 1 interferon production., PMID:20346735
Autoimmune polyendocrinopathy-candidosis-ectodermal dystrophy (APECED)--a diagnostic and therapeutic challenge., PMID:20118890
Novel sequence variation of AIRE and detection of interferon-omega antibodies in early infancy., PMID:19863576
Radioimmunoassay for autoantibodies against interferon omega; its use in the diagnosis of autoimmune polyendocrine syndrome type I., PMID:18708298
Pretreatment with feline interferon omega and the course of subsequent infection with feline herpesvirus in cats., PMID:17760705
Evaluation of inflammation and immunity in cats with spontaneous parvovirus infection: consequences of recombinant feline interferon-omega administration., PMID:17521745
Safety pharmacology, toxicology and pharmacokinetic assessment of recombinant human omega-interferon produced from CHO-SS cells., PMID:16867173
Anti-interferon autoantibodies in autoimmune polyendocrinopathy syndrome type 1., PMID:16784312
Anti-interferon auto-antibodies in autoimmune polyendocrinopathy syndrome type 1., PMID:16756392
Activity of feline interferon-omega after ocular or oral administration in cats as indicated by Mx protein expression in conjunctival and white blood cells., PMID:16740097
Incidence of autoantibodies against type I and type II interferons in a cohort of systemic lupus erythematosus patients in Slovakia., PMID:12716486
Anti-cytokine autoantibodies in autoimmunity: preponderance of neutralizing autoantibodies against interferon-alpha, interferon-omega and interleukin-12 in patients with thymoma and/or myasthenia gravis., PMID:12653847
Receptors for recombinant feline interferon-omega in hemocytes of the Japanese pearl oyster Pinctada fucata martensii., PMID:12363085
Identification of critical residues in bovine IFNAR-1 responsible for interferon binding., PMID:11278538
Sodium phosphate enhances plasmid DNA expression in vivo., PMID:10918485
Are all type I human interferons equivalent?, PMID:9658366
Natural autoantibodies to interferons., PMID:9241617
A comparison of the antiproliferative properties of recombinant human IFN-alpha 2 and IFN-omega in human bone marrow culture., PMID:9197999
An anti-cytokine bioactivity assay for interferons-alpha, -beta and -omega., PMID:8814320
Human interferon omega--a review., PMID:9345398
Interferon alpha induces rapid tyrosine phosphorylation of the vav proto-oncogene product in hematopoietic cells., PMID:7508909
A monoclonal antibody to recombinant human IFN-alpha receptor inhibits biologic activity of several species of human IFN-alpha, IFN-beta, and IFN-omega. Detection of heterogeneity of the cellular type I IFN receptor., PMID:8423335
Human interferon omega 1: isolation of the gene, expression in Chinese hamster ovary cells and characterization of the recombinant protein., PMID:1647209
Are the acid-labile interferon alpha and interferon omega-1 identical?, PMID:1994590
Purification and characterization of natural human interferon omega 1. Two alternative cleavage sites for the signal peptidase., PMID:1693148
Monoclonal antibodies and enzyme immunoassays specific for human interferon (IFN) omega 1: evidence that IFN-omega 1 is a component of human leukocyte IFN., PMID:1691561
Antigenic structure of human interferon omega 1 (interferon alpha II1): comparison with other human interferons., PMID:2438379
For research use only. Not for human or drug use.
