Catalog No.
RHC10601
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
ELISA: 1:10000, IHC: 1:200-1:1000
Target
Cytochrome P450 form 6, Hydroperoxy icosatetraenoate dehydratase, Cytochrome P450 1A1, CYP1A1, Cytochrome P450-P1, Cytochrome P450-C, CYPIA1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P04798
Applications
ELISA, IHC
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R2Y89
Mechanisms involved in pro-inflammatory responses to traffic-derived particulate matter (PM) in THP-1 macrophages compared to HBEC3-KT bronchial epithelial cells., PMID:40345318
CCL5/CCR5/CYP1A1 pathway prompts liver cancer cells to survive in the combination of targeted and immunological therapies., PMID:39183447
Lactobacillus species ameliorate membranous nephropathy through inhibiting the aryl hydrocarbon receptor pathway via tryptophan-produced indole metabolites., PMID:37594378
Impairment of aryl hydrocarbon receptor signalling promotes hepatic disorders in cancer cachexia., PMID:37127348
CYP1A1 Is a Useful Diagnostic Marker for Angiofibroma of Soft Tissue., PMID:36876749
Focal adhesion alterations in G0-positive melanoma cells., PMID:36533319
PAH-induced metabolic changes related to inflammation in childhood asthma., PMID:36136199
Discovery and Characterization of a Novel Aryl Hydrocarbon Receptor Inhibitor, IK-175, and Its Inhibitory Activity on Tumor Immune Suppression., PMID:35666806
Neurons expressing the aryl hydrocarbon receptor in the locus coeruleus and island of Calleja major are novel targets of dioxin in the mouse brain., PMID:33963922
Identification of a Sensitive Human Immunological Target of Aryl Hydrocarbon Receptor Activation: CD5+ Innate-Like B Cells., PMID:33936048
Induction and repression effects on CYP and transporter protein abundance by azole mixture uptake in rat liver., PMID:33343269
Prenatal indole-3-carbinol administration activates aryl hydrocarbon receptor-responsive genes and attenuates lung injury in a bronchopulmonary dysplasia model., PMID:33148012
Natural organic matter does not diminish the mammalian bioavailability of 2,3,7,8-tetrachlorodibenzo-p-dioxin., PMID:33032214
Gender differences in plasma pharmacokinetics and hepatic metabolism of geissoschizine methyl ether from Uncaria hook in rats., PMID:32898626
6-Formylindolo (3, 2-b) Carbazole (FICZ)-mediated protection of gut barrier is dependent on T cells in a mouse model of alcohol combined with burn injury., PMID:32711051
Cytochrome P450 1A1 enhances inflammatory responses and impedes phagocytosis of bacteria in macrophages during sepsis., PMID:32366266
Biochemical properties of human full-length aryl hydrocarbon receptor (AhR)., PMID:32289173
Simple and accurate visual detection of single nucleotide polymorphism based on colloidal gold nucleic acid strip biosensor and primer-specific PCR., PMID:31735203
Association of radiation risk in the second and third generations with polymorphisms in the genes CYP1A1, CYP2E1, GSTP1 and changes in the thyroid., PMID:31726965
Effect of Dietary Doses of Quercetin on Hepatic Drug Metabolizing Enzymes in Spontaneously Hypertensive Rats., PMID:31065969
CYP2J2 is the major enzyme in human liver microsomes responsible for hydroxylation of SYL-927, a novel and selective sphingosine 1-phosphate receptor 1 (S1P1 ) agonist., PMID:30362120
Activated carbons of varying pore structure eliminate the bioavailability of 2,3,7,8-tetrachlorodibenzo-p-dioxin to a mammalian (mouse) model., PMID:30292116
Toxicological Evaluation of Flumequine in Pubertal Male Rats After Oral Administration for Six Weeks., PMID:29978132
Roles of Aryl Hydrocarbon Receptor in Aromatase-Dependent Cell Proliferation in Human Osteoblasts., PMID:29039776
Comparison of In Vitro Hepatic Scoparone 7-O-Demethylation between Humans and Experimental Animals., PMID:28950382
Induction of Colonic Regulatory T Cells by Mesalamine by Activating the Aryl Hydrocarbon Receptor., PMID:28593185
Reprint of: CYP1A protein expression and catalytic activity in double-crested cormorants experimentally exposed to Deepwater Horizon Mississippi Canyon 252 oil., PMID:28571624
CYP1A protein expression and catalytic activity in double-crested cormorants experimentally exposed to deepwater Horizon Mississippi Canyon 252 oil., PMID:28390242
Sequestration of 2,3,7,8-tetrachlorodibenzo-p-dioxin by activated carbon eliminates bioavailability and the suppression of immune function in mice., PMID:28370362
Identification of cytochrome P450 isoforms involved in the metabolism of Syl930, a selective S1PR1 agonist acting as a potential therapeutic agent for autoimmune encephalitis., PMID:28126315
Aryl hydrocarbon receptor is required for optimal B-cell proliferation., PMID:27875245
Quinone-mediated induction of cytochrome P450 1A1 in HepG2 cells through increased interaction of aryl hydrocarbon receptor with aryl hydrocarbon receptor nuclear translocator., PMID:27853106
Induced expression of microsomal cytochrome b5 determined at mRNA and protein levels in rats exposed to ellipticine, benzo[a]pyrene, and 1-phenylazo-2-naphthol (Sudan I)., PMID:27110040
Areca nut components stimulate ADAM17, IL-1α, PGE2 and 8-isoprostane production in oral keratinocyte: role of reactive oxygen species, EGF and JAK signaling., PMID:26919242
Fish condition factor, peroxisome proliferator activated receptors and biotransformation responses in Sarotherodon melanotheron from a contaminated freshwater dam (Awba Dam) in Ibadan, Nigeria., PMID:26898991
Application of Various Statistical Models to Explore Gene-Gene Interactions in Folate, Xenobiotic, Toll-Like Receptor and STAT4 Pathways that Modulate Susceptibility to Systemic Lupus Erythematosus., PMID:26689915
Aryl Hydrocarbon Receptor Protects Lungs from Cockroach Allergen-Induced Inflammation by Modulating Mesenchymal Stem Cells., PMID:26561548
Covalent binding of quinones activates the Ah receptor in Hepa1c1c7 cells., PMID:26558468
Evaluation of Risk Factors for Nasopharyngeal Carcinoma in a High-risk Area of India, the Northeastern Region., PMID:26163617
[FEATURES OF THE IMMUNE GENETIC PARAMETERS IN WORKERS IN NON-FERROUS METAL INDUSTRY]., PMID:26155646
Identification of Putative ORF5 Protein of Porcine Circovirus Type 2 and Functional Analysis of GFP-Fused ORF5 Protein., PMID:26035722
Enzymatic characterization of in vitro-expressed Baikal seal cytochrome P450 (CYP) 1A1, 1A2, and 1B1: implication of low metabolic potential of CYP1A2 uniquely evolved in aquatic mammals., PMID:25814058
The aryl hydrocarbon receptor regulates an essential transcriptional element in the immunoglobulin heavy chain gene., PMID:25749007
The catecholestrogen, 2-hydroxyestradiol-17beta, acts as a G protein-coupled estrogen receptor 1 (GPER/GPR30) antagonist to promote the resumption of meiosis in zebrafish oocytes., PMID:25609836
DDE and PCB 153 independently induce aryl hydrocarbon receptor (AhR) expression in peripheral blood mononuclear cells., PMID:25316167
[DIO2, TPO, CYP1A1 AND CYP1A2 gene polymorphism in women with thyroid disease]., PMID:25306702
3, 3'-Diindolylmethane alleviates steatosis and the progression of NASH partly through shifting the imbalance of Treg/Th17 cells to Treg dominance., PMID:25281898
Characterization of arachidonic acid metabolism by rat cytochrome P450 enzymes: the involvement of CYP1As., PMID:24969701
Altered substrate specificity of the Pterygoplichthys sp. (Loricariidae) CYP1A enzyme., PMID:24911589
Transient suppression of AHR activity in early red seabream embryos does not prevent the disruption of peripheral nerve projection by 2,3,7,8-tetrachlorodibenzo-p-dioxin., PMID:24858342
For research use only. Not for human or drug use.
