Catalog No.
RHC06204
Species reactivity
Human, Mouse, Rat, Monkey
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
WB: 1:500-1:1000
Target
LPC1, Calpactin-2, Lipocortin I, ANX1, ANXA1, Phospholipase A2 inhibitory protein, Chromobindin-9, Annexin I, Annexin A1, p35, Calpactin II, Annexin-1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P04083
Applications
WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.5% BSA, 0.05% Sodium Azide and 50% Glycerol.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R2Y53
Eosinophils-Induced Lumican Secretion by Synovial Fibroblasts Alleviates Cartilage Degradation via the TGF-β Pathway Mediated by Anxa1 Binding., PMID:40125663
Mesenchymal stem cells from perinatal tissues promote diabetic wound healing via PI3K/AKT activation., PMID:39923118
Investigation of circulating natural autoantibodies against ANXA1 and MYC as potential biomarkers in hepatocellular carcinoma., PMID:39824386
Laboratory measurement of autoantibodies to Annexin A1: Review and measurements in health and COVID-19., PMID:39520946
Loss of Annexin A1 in macrophages restrains efferocytosis and remodels immune microenvironment in pancreatic cancer by activating the cGAS/STING pathway., PMID:39237260
A therapeutic antibody targeting annexin-A1 inhibits cancer cell growth in vitro and in vivo., PMID:38200229
ANXA1-derived peptide for targeting PD-L1 degradation inhibits tumor immune evasion in multiple cancers., PMID:37001908
Contribution of plasma, placental, inflammatory and pro-resolving mediators in labor induction., PMID:35390665
HDX-MS for Epitope Characterization of a Therapeutic ANTIBODY Candidate on the Calcium-Binding Protein Annexin-A1., PMID:33808657
2-Methoxyestradiol Protects Against Lung Ischemia/Reperfusion Injury by Upregulating Annexin A1 Protein Expression., PMID:33796096
Serum IgG2 antibody multi-composition in systemic lupus erythematosus and in lupus nephritis (Part 2): prospective study., PMID:33351137
Immunoproteomics approach revealed elevated autoantibody levels against ANXA1 in early stage gallbladder carcinoma., PMID:33261560
Annexin A1-dependent tethering promotes extracellular vesicle aggregation revealed with single-extracellular vesicle analysis., PMID:32938681
Monoclonal antibody therapy that targets phospholipid-binding protein delays lupus activity in MRL/lpr mice., PMID:32533866
Upregulation of annexin A1 protein expression in the intratumoral vasculature of human non-small-cell lung carcinoma and rodent tumor models., PMID:32497150
Proteomic analysis of neutrophils in ANCA-associated vasculitis reveals a dysregulation in proteinase 3-associated proteins such as annexin-A1 involved in apoptotic cell clearance., PMID:31142442
Lack of Endogenous Annexin A1 Increases Mast Cell Activation and Exacerbates Experimental Atopic Dermatitis., PMID:30650525
Annexin A1-suppressed autophagy promotes nasopharyngeal carcinoma cell invasion and metastasis by PI3K/AKT signaling activation., PMID:30459351
Resolution of inflammation in neuromyelitis optica spectrum disorders., PMID:30300851
Increased Levels of Circulating Anti-ANXA1 IgG Antibody in Patients with Non-Small Cell Lung Cancer., PMID:29945332
[Expression of annexin A1 in peripheral blood cells of Naïve rheumatoid arthritis patients and its influencing factors]., PMID:28693070
Circulating Antibodies to Linear Peptide Antigens Derived from ANXA1 and FOXP3 in Lung Cancer., PMID:28551657
Characterization of Ostertagia ostertagi annexin-like proteins at different developmental stages., PMID:28378195
Annexin A1 promotes timely resolution of inflammation in murine gout., PMID:27995621
Interaction between ANXA1 and GATA-3 in Immunosuppression of CD4+ T Cells., PMID:27833268
Loss of ARID1A Activates ANXA1, which Serves as a Predictive Biomarker for Trastuzumab Resistance., PMID:27172896
Role of the protein annexin A1 on the efficacy of anti-TNF treatment in a murine model of acute colitis., PMID:27343762
Proteomic analysis of fine-needle aspiration in differential diagnosis of thyroid nodules., PMID:27172385
A novel anti-inflammatory mechanism of high density lipoprotein through up-regulating annexin A1 in vascular endothelial cells., PMID:27012521
[Changes in the expression of three markers in T lymphocytes of peripheral blood and immunoregulatory mechanisms of burned mice with sepsis at early stage]., PMID:26902275
The role of the Annexin-A1/FPR2 system in the regulation of mast cell degranulation provoked by compound 48/80 and in the inhibitory action of nedocromil., PMID:26803520
Cross-linking of glycosphingolipids at the plasma membrane: consequences for intracellular signaling and traffic., PMID:26407609
Integrative proteomic and gene expression analysis identify potential biomarkers for adjuvant trastuzumab resistance: analysis from the Fin-her phase III randomized trial., PMID:26358523
Activation of annexin A1 signalling in renal fibroblasts exerts antifibrotic effects., PMID:26332853
Membrane proteome analysis of glioblastoma cell invasion., PMID:25853691
Beneficial effect of annexin A1 in a model of experimental allergic conjunctivitis., PMID:25795053
Annexin-A1 restricts Th17 cells and attenuates the severity of autoimmune disease., PMID:25619792
Role of intracellular and extracellular annexin A1 in migration and invasion of human pancreatic carcinoma cells., PMID:25510623
Investigation of circulating antibodies to ANXA1 in breast cancer., PMID:25344217
Detection of circulating antibodies to linear peptide antigens derived from ANXA1 and DDX53 in lung cancer., PMID:24453033
Dysregulation of anti-inflammatory annexin A1 expression in progressive Crohns Disease., PMID:24130820
Anti-allergic cromones inhibit histamine and eicosanoid release from activated human and murine mast cells by releasing Annexin A1., PMID:23527056
Annexin A1 mediates the anti-adhesive effects of the dexamethasone-treated promyelocytic leukemic cells., PMID:22991072
High calcium enhances calcium oxalate crystal binding capacity of renal tubular cells via increased surface annexin A1 but impairs their proliferation and healing., PMID:22640262
Annexin A1 modulates natural and glucocorticoid-induced resolution of inflammation by enhancing neutrophil apoptosis., PMID:22493082
Annexin A1 mediates the anti-inflammatory effects during the granulocytic differentiation process in all-trans retinoic acid-treated acute promyelocytic leukemic cells., PMID:22378018
Annexin-1-deficient mice exhibit spontaneous airway hyperresponsiveness and exacerbated allergen-specific antibody responses in a mouse model of asthma., PMID:22092555
Suppression of MIP-2 or IL-8 production by annexins A1 and A4 during coculturing of macrophages with late apoptotic human peripheral blood neutrophils., PMID:22056994
α-MSH inhibits TNF-α-induced maturation of human dendritic cells in vitro through the up-regulation of ANXA1., PMID:21131366
Annexin A1: a central player in the anti-inflammatory and neuroprotective role of microglia., PMID:20962261
For research use only. Not for human or drug use.
