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Anti-ESR1/ER-alpha Antibody (R2Y36)

Catalog #:   RHC03205 Specific References (48) DATASHEET
Host species: Mouse
Isotype: IgG2b
Applications: WB
Accession: P03372
Overview

Catalog No.

RHC03205

Species reactivity

Human

Host species

Mouse

Isotype

IgG2b

Clonality

Monoclonal

Tested applications

WB: 1:500-1:2000

Target

Estrogen receptor, ER-alpha, ESR, ER, ESR1, Nuclear receptor subfamily 3 group A member 1, NR3A1, Estradiol receptor

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P03372

Applications

WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R2Y36

Data Image
References

Nivolumab plus low-dose ipilimumab in hypermutated HER2-negative metastatic breast cancer: a phase II trial (NIMBUS)., PMID:40360544

MUC1-C dependency in drug resistant HR+/HER2- breast cancer identifies a new target for antibody-drug conjugate treatment., PMID:40287441

Novel Estrogen Receptor - Targeted Therapies in Hormone-Receptor Positive Breast Cancer., PMID:40163189

Upregulation of miR-99b-5p Modulates ESR1 Expression as an Adaptive Mechanism to Circumvent Drug Response via Facilitating ER/HER2 Crosstalk., PMID:40033677

Prediction of Response to Anti-HER2 Therapy Using A Multigene Assay., PMID:39826800

Integration of Immune Responses and Transcriptomic Signatures Reveals the Efficacy of Maternal Genetic Vaccination in a Pregnant Model and Its Neonates., PMID:39762199

A therapeutic algorithm guiding subsequent therapy selection after CDK4/6 inhibitors' failure: A review of current and investigational treatment for HR+/Her2- breast cancer., PMID:39433229

Precision therapeutics and emerging strategies for HR-positive metastatic breast cancer., PMID:39179659

Electrochemical aptasensor based on a dual signal amplification strategy of 1-AP-CNHs and ROP for highly sensitive detection of ERα., PMID:39128408

Investigating the therapeutic mechanism of Jiedu-Quyu-Ziyin Fang on systemic lupus erythematosus through the ERα-miRNA-TLR7 immune axis., PMID:38948043

Characterization of Potential Target Genes of Borneol in Increasing Trastuzumab Sensitivity in HER2+ Trastuzumab-Resistant Breast Cancer: Bioinformatics and In Vitro Studies., PMID:38809634

Bioinformatics and In Vitro Study Reveal ERα as The Potential Target Gene of Honokiol to Enhance Trastuzumab Sensitivity in HER2+ Trastuzumab-Resistant Breast Cancer Cells., PMID:38805864

PACE: A Randomized Phase II Study of Fulvestrant, Palbociclib, and Avelumab After Progression on Cyclin-Dependent Kinase 4/6 Inhibitor and Aromatase Inhibitor for Hormone Receptor-Positive/Human Epidermal Growth Factor Receptor-Negative Metastatic Breast Cancer., PMID:38513188

Sexual-biased necroinflammation is revealed as a predictor of bevacizumab benefit in glioblastoma., PMID:38411438

Current and emerging treatment approaches for hormone receptor-positive/human epidermal growth factor receptor 2-negative metastatic breast cancer., PMID:38211404

Multiple-Pathway Synergy Alters Steroidogenesis and Spermatogenesis in Response to an Immunocastration Vaccine in Goat., PMID:38201210

Dulaglutide as a demethylating agent to improve the outcome of breast cancer., PMID:38174426

Integrated Molecular Characterization of HER2-Low Breast Cancer Using Next Generation Sequencing (NGS)., PMID:38137385

Exploring the Spatial Landscape of the Estrogen Receptor Proximal Proteome With Antibody-Based Proximity Labeling., PMID:38122900

Estrogen receptor positive breast cancer: contemporary nuances to sequencing therapy., PMID:38103078

Estrogen receptor and programmed death ligand-1 expression in type 1 endometrial cancer and its associated clinicopathological characteristics., PMID:37797425

UPLC-Q-TOF-MS, network analysis, and molecular docking to investigate the effect and active ingredients of tea-seed oil against bacterial pathogens., PMID:37745048

Sequencing systemic therapy in hormone-receptor positive metastatic breast cancer: a modern paradigm., PMID:37574571

An Analysis of Clinical and Pathologic Features, RecurIndex Genomic Profiles, and Survival Outcomes in HER2-Low Breast Cancer., PMID:37279952

Plasma ESR1 mutations and outcome to first-line paclitaxel and bevacizumab in patients with advanced ER-positive/HER2-negative breast cancer., PMID:37226020

Cell State Transitions and Phenotypic Heterogeneity in Luminal Breast Cancer Implicating MicroRNAs as Potential Regulators., PMID:36834918

Molecular Profile and Matched Targeted Therapy for Advanced Breast Cancer Patients., PMID:36826152

The Co-Expression of Estrogen Receptors ERα, ERβ, and GPER in Endometrial Cancer., PMID:36769338

A novel estrogen receptor 1: sphingomyelin phosphodiesterase acid-like 3B pathway mediates rituximab response in myositis patients., PMID:36478205

Effects of the synthetic progestin levonorgestrel on some aspects of thyroid physiology in common carp (Cyprinus carpio)., PMID:36244424

Sex differences in saliva-based DNA methylation changes and environmental stressor in young African American adults., PMID:36067197

Biomarkers for Systemic Therapy in Metastatic Breast Cancer: ASCO Guideline Update., PMID:35759724

Pituitary luteinizing hormone synthesis starts in aromatase (cyp19a1b)-positive cells expressing esr1 and esr2b at the onset of puberty in Takifugu rubripes (fugu)., PMID:35552517

Periodontitis promotes the expression of gingival transmembrane serine protease 2 (TMPRSS2), a priming protease for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)., PMID:35472469

IL-27 promotes decidualization via the STAT3-ESR/PGR regulatory axis., PMID:35430461

Detection of Circulating HPV16 DNA as a Biomarker for Cervical Cancer by a Bead-Based HPV Genotyping Assay., PMID:35225653

Detection and Functional Analysis of Estrogen Receptor α Phosphorylated at Serine 216 in Mouse Neutrophils., PMID:35119660

Immunoprecipitation Analyses of Estrogen Receptor α Phosphorylated at Serine 216 in the Mouse Liver., PMID:35119658

Estrogen-Responsive Gene MAST4 Regulates Myeloma Bone Disease., PMID:35064934

Association Between Estrogen Receptors and GATA3 in Bladder Cancer: A Systematic Review and Meta-Analysis of Their Clinicopathological Significance., PMID:34690921

Endocrine resistance in breast cancer: from molecular mechanisms to therapeutic strategies., PMID:34623477

The Immunohistochemical Expression of MCM-3, -5, and -7 Proteins in the Uterine Fibroids., PMID:34449552

Genomic, Transcriptomic, and Proteomic Profiling of Metastatic Breast Cancer., PMID:33782032

MOF upregulates the estrogen receptor α signaling pathway by its acetylase activity in hepatocellular carcinoma., PMID:33544437

Chemotherapy induces dynamic immune responses in breast cancers that impact treatment outcome., PMID:33268821

The Role of Autophagy-Mediated Dengue Virus Antibody-Dependent Enhancement Infection of THP-1 Cells., PMID:33202415

Management of Brain and Leptomeningeal Metastases from Breast Cancer., PMID:33198331

Effect of body mass index on response to neo-adjuvant therapy in HER2-positive breast cancer: an exploratory analysis of the NeoALTTO trial., PMID:33109233

Datasheet
$ 220
Product specifications
50 μg 220 100 μg 350

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For research use only. Not for human or drug use.

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Anti-ESR1/ER-alpha Antibody (R2Y36) [RHC03205]
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