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Anti-LAYN/Layilin Antibody (R2X66)

Catalog #:   RHB96503 Specific References (4) DATASHEET
Host species: Mouse
Isotype: IgG2b
Applications: IHC, IP, WB
Accession: Q6UX15
Overview

Catalog No.

RHB96503

Species reactivity

Human

Host species

Mouse

Isotype

IgG2b

Clonality

Monoclonal

Tested applications

IHC: 1:100-1:200, IP: 1:100-1:200, WB: 1:500-1:1000

Target

LAYN, Layilin

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q6UX15

Applications

IHC, IP, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R2X66

Data Image
  • Immunohistochemical
    IHC-P analysis of stomach tissue by LAYN antibody (RHB96503). IHC-P was performed using sections of the formalin-fixed paraffin-embedded stomach tissue;Result: Glandular cells are positively stained at the cytoplasm.
  • Immunoprecipitation
    Lane 1: K-562 lysate; Lane 2: LAYN immunoprecipitated from K-562 lysate by RHB96503;Lane 3: The same as Lane 2 but use IgG isotype control antibody;Result: RHB96503 can immunoprecipitate LAYN;
  • Western blot
    Lane 1: 15 µg of MCF7 lysate; Lane 2: 15 µg of U-251MG lysate; Lane 3: 15 µg of K-562 lysate; Result: RHB96503 can detect LAYN by Western blotting;
References

Elevated Layilin-Positive Monocyte Levels in the Peripheral Blood of Patients with Systemic Lupus Erythematosus Reflect Their Autoimmune Status., PMID:37642473

Targeting LAYN inhibits colorectal cancer metastasis and tumor-associated macrophage infiltration induced by hyaluronan oligosaccharides., PMID:36805871

Low-dose anti-VEGFR2 therapy promotes anti-tumor immunity in lung adenocarcinoma by down-regulating the expression of layilin on tumor-infiltrating CD8+T cells., PMID:36260222

Secretion of inflammatory factors from chondrocytes by layilin signaling., PMID:25150153

Datasheet
$ 220
Product specifications
50 μg 220 100 μg 350

Contact Information

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Mail: support@antibodysystem.com

Distributor list

For research use only. Not for human or drug use.

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Anti-LAYN/Layilin Antibody (R2X66) [RHB96503]
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