Identification of a direct interaction between the Fab domains of IgG antibodies and human FcRn upon IgG-FcRn complex formation., PMID:40506471
Pan-H7 influenza human antibody virus neutralization depends on avidity and steric hindrance., PMID:40471690
Efgartigimod combined with steroids as a fast-acting therapy for anti-SRP immune-mediated necrotizing myopathy., PMID:40470493
A bioactive soluble recombinant mouse LIGHT promotes effective tumor immune cell infiltration delaying tumor growth., PMID:40457031
Impact of Vaccine-Elicited Anti-Spike IgG4 Antibodies on Fc-Effector Functions Against SARS-CoV-2., PMID:40431678
Fate of Stressed Oligoclonal Antibodies Tracked by Fluorescence Cross-Correlation Spectroscopy: IgG Aggregation Proceeds across the Species Barrier., PMID:40408563
Real world study in Italian public hospital with Efgartigimod in patients affected by generalized myasthenia gravis: influence of clinical and serological factors., PMID:40401017
Antibody Labeling With FITC Facilitates Controlled Release From Peptide Hydrogels Bearing Fc-Binding Motifs., PMID:40400208
Molecular determinants of sialylated IgG anti-inflammatory activity., PMID:40377989
Engineering of long-acting human growth hormone-Fc fusion proteins: Effects of valency, fusion position, and linker design on pharmacokinetics and efficacy., PMID:40373007
Increasing the developability of lambda chain antibodies: engineering to confer protein L binding activity and its consequences., PMID:40368210
Comparison of antibody-scTRAIL Fc fusion proteins with varying valency for EGFR and TRAIL receptors., PMID:40328809
Leveraging neonatal Fc receptor (FcRn) to enhance antibody transport across the blood brain barrier., PMID:40319060
Design of an Fc Mutation to Abrogate Fcγ Receptor Binding Based on Residue Interaction Network Analysis., PMID:40300090
The contemporary management of haemolytic disease of the fetus and newborn., PMID:40263127
Serum Disease-Specific IgG Fc Glycosylation as Potential Biomarkers for Nonproliferative and Proliferative Diabetic Retinopathy Using Mass Spectrometry., PMID:40204274
Neonatal Fc receptor participates in endocytosis of Fc fusion protein in vivo and in vitro., PMID:40187220
Molecular parameters governing antibody FcγR signaling and effector functions in the context of HIV envelope., PMID:40158219
Rapid In Vivo Screening of Monoclonal Antibody Cocktails Using Hydrodynamic Delivery of DNA-Encoded Modified Antibodies., PMID:40149613
Plant-derived recombinant macromolecular PAP-IgG Fc as a novel prostate cancer vaccine candidate eliciting robust immune responses., PMID:40140219
Pharmacodynamics, pharmacokinetics, and toxicology of Fc-growth hormone fusion protein in macaques., PMID:40120208
23ME-01473, an Fc Effector-Enhanced Anti-ULBP6/2/5 Antibody, Restores NK Cell-Mediated Antitumor Immunity through NKG2D and FcγRIIIa Activation., PMID:40116579
Anti-CD64(scFv)-SNAP-Auristatin F: An in vitro proof of concept study for a recombinant antibody conjugate targeting CD64+ acute monocytic leukemia., PMID:40112664
Fc fragment of IgG binding protein suppresses tumor growth by stabilizing wild type P53 in colorectal cancer cells., PMID:40108539
Novel, fully human, anti-PfCSP antibodies with potent antimalarial activity using a phage display based strategy., PMID:40101454
An Enhanced Bimetallic Optical Fiber SPR Biosensor Using Graphene Oxide for the Label-Free and Sensitive Detection of Human IgG., PMID:40096495
Targeting prostate cancer by new bispecific monocyte engager directed to prostate-specific membrane antigen., PMID:40096254
Rheumatoid Factor: Diagnostic and Prognostic Performance and Therapeutic Implications in Rheumatoid Arthritis., PMID:40094988
Engineering and Structural Elucidation of a Sac7d-Derived IgG Fc-Specific Affitin and Its Application for the Light-Controlled Affinity Purification of Antibodies., PMID:40085144
Intradermal delivery of SARS-CoV-2 RBD3-Fc mRNA vaccines via a needle-free injection system induces robust immune responses in rats., PMID:40034698
Impact of FcRn antagonism on vaccine-induced protective immune responses against viral challenge in COVID-19 and influenza mouse vaccination models., PMID:40028815
Increased SARS-CoV-2 IgG4 has variable consequences dependent upon Fc function, Fc receptor polymorphism, and viral variant., PMID:40009690
Fc-engineered large molecules targeting blood-brain barrier transferrin receptor and CD98hc have distinct central nervous system and peripheral biodistribution., PMID:39979268
Cell-based glycoengineering for production of homogeneous and specific glycoform-enriched antibodies with improved effector functions., PMID:39969996
Effects of efgartigimod treatment on humoral and cellular immune responses: analysis of T-cell-dependent antibody response in cynomolgus monkeys., PMID:39945037
Nipocalimab, an immunoselective FcRn blocker that lowers IgG and has unique molecular properties., PMID:39936406
Reducing IgG accumulation via neonatal Fc receptor (FcRn) blockade relieves neuropathic pain., PMID:39870199
Engineered protein G variants for multifunctional antibody-based assemblies., PMID:39865354
Enhanced Immunogenicity and Affinity with A35R-Fc-Based Chimeric Protein Compared to MPXV A35R Protein., PMID:39861905
Fc-binding nanodisc restores antiviral efficacy of antibodies with reduced neutralizing effects against evolving SARS-CoV-2 variants., PMID:39856746
Development of a time-resolved fluoroimmunoassay for rituximab and its application to therapeutic drug monitoring., PMID:39842652
First-in-human phase I trial of the bispecific CD47 inhibitor and CD40 agonist Fc-fusion protein, SL-172154 in patients with platinum-resistant ovarian cancer., PMID:39800375
What is rheumatoid factor? From screening to personalized management., PMID:39792161
Establishment of Time-Resolved Fluorescence Immunoassay for Thyrotropin Receptor Antibodies and Clinical Application., PMID:39776097
Branched Linkers for Homogeneous Antibody-Drug Conjugates: How Long Is Long Enough?, PMID:39769122
The novel CD16A/anti-CD3 bifunctional protein, eCD16A/anti-CD3-BFP, redirects T cell cytotoxicity toward antibody-bound target cells., PMID:39763374
Acquisition of Fc-afucosylation of PfEMP1-specific IgG is age-dependent and associated with clinical protection against malaria., PMID:39747065
Identification of the linear Fc-binding epitope on the bovine IgG1 Fc receptor of (boFcγRI) using synthetic peptides., PMID:39746504
The relationship between drug-induced immunogenicity and hypersensitivity reactions and skin tests related to infliximab, etanercept and adalimumab in patients with rheumatoid arthritis and ankylosing spondylitis., PMID:39734351
Modification of Fc-fusion protein structures to enhance efficacy of cancer vaccine in plant expression system., PMID:39724301
For research use only. Not for human or drug use.
