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Anti-POMC/ACTH Antibody (R2X26)

Catalog #:   RHB92204 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG1
Applications: ELISA, FCM, IHC
Accession: P01189
Overview

Catalog No.

RHB92204

Species reactivity

Human

Host species

Mouse

Isotype

IgG1

Clonality

Monoclonal

Tested applications

ELISA: 1:10000, FCM: 1:200-1:400, IHC: 1:200-1:1000

Target

Melanotropin alpha, Beta-MSH, Gamma-MSH, Beta-LPH, Melanotropin beta, Adrenocorticotropic hormone, Pro-opiomelanocortin, ACTH, CLIP, Gamma-LPH, Corticotropin-lipotropin, Alpha-MSH, POMC

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P01189

Applications

ELISA, FCM, IHC

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R2X26

Data Image
  • Flow Cytometry
    Flow cytometric analysis of K562 cells using ACTH mouse mAb (green) and negative control (red).
  • Immunohistochemical
    Immunohistochemical analysis of paraffin-embedded human hypophysis tissues using ACTH mouse mAb with DAB staining.
References

Sarcoptic mange in cattle: Effects of treatment with eprinomectin topical solution on performance, behavior changes, and adrenal and systemic responses to ACTH challenge., PMID:40252507

PD-1 inhibitor-induced thyroiditis and ACTH deficiency., PMID:40000036

Dominant Expression of Chromogranin B in Pituitary Corticotrophs and Its Putative Role in Interaction With Secretogranin III., PMID:39791490

Optimising Growth, Immunity, and Gene Expression in Broiler Chickens Through Dietary Threonine Levels and Oil Inclusion., PMID:39501595

Structure elucidation of a human melanocortin-4 receptor specific orthosteric nanobody agonist., PMID:39353917

Initial development of a rapid, portable, stall-side ELISA for the measurement of equine adrenocorticotropic hormone., PMID:39320416

Schmidt´s syndrome found by tan: a case report., PMID:39315067

Neuroendocrinology of bone., PMID:39096452

The detection of ACTH and insulin in equine plasma by solid-phase extraction and micro-flow LC/MSMS., PMID:38978168

Pituitary-adrenal axis dysfunction induced by tislelizumab immunotherapy for non-small cell lung cancer: a case series and literature review., PMID:38977996

Pseudo Elevation of TSH and ACTH Caused by Heterophilic Antibodies: a Case Report and Literature Review., PMID:38868895

Long-Term Dynamics of Serum α-MSH and α-MSH-Binding Immunoglobulins with a Link to Gut Microbiota Composition in Patients with Anorexia Nervosa., PMID:38852579

Immune checkpoint inhibitor-induced hypophysitis with transient ACTH-dependent hypercortisolism., PMID:38772867

Analysis of Natural Antibodies during the Development of Phantom Pain Syndrome., PMID:38744736

Global, neuronal or β cell-specific deletion of inceptor improves glucose homeostasis in male mice with diet-induced obesity., PMID:38418586

The endogenous opioid system in the medial prefrontal cortex mediates ketamine's antidepressant-like actions., PMID:38346984

Immune checkpoint inhibitor-induced isolated adrenocorticotropic hormone deficiency: a systematic review., PMID:38318292

Human placenta releases extracellular vesicles carrying corticotrophin releasing hormone mRNA into the maternal blood., PMID:38190772

Idiopathic isolated adrenocorticotropic hormone deficiency: a systematic review of a heterogeneous and underreported disease., PMID:38151529

Fulminant ACTH decrease following diabetic ketoacidosis induced by immune checkpoint inhibitor combination therapy with nivolumab and ipilimumab: A case report., PMID:38134115

Detecting the interferences in adrenocorticotropic hormone measurement - three cases reinforcing the efficiency of the complementary clinical and laboratory audit., PMID:38125613

Paraneoplastic isolated adrenocorticotropic hormone deficiency revealed after immune checkpoint inhibitors therapy: new insights into anti-corticotroph antibody., PMID:38035072

Multiple immunoassay interference in a patient with falsely elevated calcitonin., PMID:37988668

Myasthenic crisis in thymoma-associated myasthenia gravis: a multicenter retrospective cohort study., PMID:37783628

Heterogeneity of TPIT expression in ACTH-secreting extra-pituitary neuroendocrine tumors (NETs) supports the existence of different cellular programs in pancreatic and pulmonary NETs., PMID:37726450

Isolated autoimmune adrenocorticotropic hormone deficiency: A positive predictor of survival among cancer patients treated with checkpoint inhibitors., PMID:37352903

Comparative Determination of Natural Antibodies for the Assessment of the Cardiovascular System and the Level of Human Difficulty., PMID:37340297

Deficient anterior pituitary with common variable immune deficiency (DAVID syndrome): a new case and literature reports., PMID:37322808

Pregnancy complicated with adrenal adenoma causing ACTH-independent Cushing's syndrome, accompanied by obstetric antiphospholipid syndrome and severe pre-eclampsia: case report and literature review., PMID:37274343

Peak Serum Cortisol Cutoffs to Diagnose Adrenal Insufficiency Across Different Cortisol Assays in Children., PMID:37218135

Paraneoplastic autoimmune hypophysitis: a novel form of paraneoplastic endocrine syndrome., PMID:37045779

Isolated Adrenocorticotropic Hormone Deficiency Associated with Atezolizumab and Bevacizumab Administration for Treating Hepatocellular Carcinoma: A Case Series., PMID:37032085

Local analgesia of electroacupuncture is mediated by the recruitment of neutrophils and released β-endorphins., PMID:37027145

Adrenal insufficiency in thyroid cancer patients treated with tyrosine kinase inhibitors and detected by ACTH stimulation test., PMID:36809657

Short Communication: Identification of equine corticotropin-like intermediate lobe peptide (CLIP) binding to an adrenocortipcotrophic hormone (ACTH) assay capture antibody., PMID:36745973

Newly diagnosed autoimmune Addison's disease in a patient with COVID-19 with autoimmune disseminated encephalomyelitis., PMID:36593594

Clinical characteristics of adrenal insufficiency induced by pembrolizumab in non-small-cell lung cancer., PMID:36523162

Isolated adrenocorticotropic hormone deficiency and sialadenitis associated with nivolumab: a case report., PMID:36482425

Negative Modulation of B Cell Activation by Melanocortin 1 Receptor Signaling Protects against Membranous Nephropathy., PMID:36446431

Addison's disease triggered by infection with mycobacterium abscessus, but not by adrenal tuberculosis or MAC pulmonary disease, in a subject with type 2 diabetes mellitus: case report., PMID:36274124

Crotalphine Modulates Microglia M1/M2 Phenotypes and Induces Spinal Analgesia Mediated by Opioid-Cannabinoid Systems., PMID:36232883

MicroRNA-7 regulates melanocortin circuits involved in mammalian energy homeostasis., PMID:36175420

Independent Skeletal Actions of Pituitary Hormones., PMID:36168775

Primary adrenal insufficiency masking as an adrenal B-cell lymphoma., PMID:36167431

Isolated adrenocorticotropic hormone deficiency associated with sintilimab therapy in a patient with advanced lung adenocarcinoma: a case report and literature review., PMID:36153581

Type 1 diabetes associated with immune checkpoint inhibitors for malignant melanoma: A case report and review of 8 cases., PMID:36107581

Toxicity in Takifugu rubripes exposed to acute ammonia: Effects on immune responses, brain neurotransmitter levels, and thyroid endocrine hormones., PMID:36063614

[Isolated ACTH deficiency clinically presented as stiff-person syndrome, successfully treated by hormonal replacement: a case report]., PMID:36031381

Aggressive pituitary tumours and carcinomas, characteristics and management of 171 patients., PMID:36018781

Assessment of adrenal function in pediatric cancer survivors., PMID:35942830

Datasheet
$ 220
Product specifications
50 μg 220 100 μg 350

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For research use only. Not for human or drug use.

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Anti-POMC/ACTH Antibody (R2X26) [RHB92204]
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