Anti-PNP Antibody (R2W70)

Catalog No.

RHB86502

Species reactivity

Human

Host species

Mouse

Isotype

IgG1

Clonality

Monoclonal

Tested applications

WB: 1:500-1:1000

Target

Inosine-guanosine phosphorylase, NP, Purine nucleoside phosphorylase, PNP, Inosine phosphorylase

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P00491

Applications

WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R2W70

Influence of Pharmacokinetic-Pharmacodynamic Failure Mechanisms on Outcomes in Biologic Therapy Sequencing in Inflammatory Bowel Disease: A Retrospective Cohort Study., PMID:40531271

Lupus anticoagulant testing in Belgian laboratories: a comparison with the 2020 International Society on Thrombosis and Haemostasis Scientific and Standardization Committee (ISTH-SSC) guidelines., PMID:40525382

Engineering Sustained-Release Broadly Neutralizing Antibody Formulations., PMID:40501883

Spatially Tuned Localization of Interleukins and OX40 Agonists Enhances Synergistic Anti-Tumor Immunity., PMID:40475557

Validity and Responsiveness of Balance Measurements Using Posturography in Patients With Immune-Mediated Neuropathies., PMID:40420525

Complete Resolution of Atypical Paraneoplastic Pemphigus Following Treatment With Dupilumab., PMID:40264631

The genetic, biophysical and immunological studies of a self-adjuvanted protein nanoparticle., PMID:40262373

Sustained Vaccine Exposure Elicits More Rapid, Consistent, and Broad Humoral Immune Responses to Multivalent Influenza Vaccines., PMID:40091614

A strain-transcending anti-AMA1 human monoclonal antibody neutralizes malaria parasites independent of direct RON2L receptor blockade., PMID:40020675

Unicentric Castleman disease-associated paraneoplastic pemphigus successfully managed with surgical resection and rituximab., PMID:40010754

Oral Paraneoplastic Pemphigus: A Scoping Review on Pathogenetic Mechanisms and Histo-Serological Profile., PMID:39584995

A systematic review of paraneoplastic pemphigus and paraneoplastic autoimmune multiorgan syndrome: Clinical features and prognostic factors., PMID:39426525

Polyneuropathy in systemic sclerosis: exploring the causes and biomarkers., PMID:39156689

A polymeric nanoplatform enhances the cGAS-STING pathway in macrophages to potentiate phagocytosis for cancer immunotherapy., PMID:39038546

Multimodal evaluation of blood-brain barrier opening in mice in response to low-intensity ultrasound and a claudin-5 binder., PMID:38961889

Engineering a human P2X2 receptor with altered ligand selectivity in yeast., PMID:38556082

Highly efficient dual-mode detection of AFB1 based on the inner filter effect: Donor-acceptor selection and application., PMID:38462339

Double-layered N-S1 protein nanoparticle immunization elicits robust cellular immune and broad antibody responses against SARS-CoV-2., PMID:38291444

Nanoparticle-Conjugated Toll-Like Receptor 9 Agonists Improve the Potency, Durability, and Breadth of COVID-19 Vaccines., PMID:38215338

NXT007-mediated hemostatic potential is suppressed by activated protein C-catalyzed inactivation of activated factor V., PMID:38115953

Identification of hyperosmotic stress-responsive genes in Chinese hamster ovary cells via genome-wide virus-free CRISPR/Cas9 screening., PMID:37709005

Structure-based design of a strain transcending AMA1-RON2L malaria vaccine., PMID:37660103

Paraneoplastic pemphigus/paraneoplastic autoimmune multiorgan syndrome: Part I. Clinical overview and pathophysiology., PMID:37597771

Myelin barrier breakdown, mechanical hypersensitivity, and painfulness in polyneuropathy with claudin-12 deficiency., PMID:37527762

Cell wall and immune modulation by Rv1800 (PPE28) helps M. smegmatis to evade intracellular killing., PMID:37455004

Broad and Durable Humoral Responses Following Single Hydrogel Immunization of SARS-CoV-2 Subunit Vaccine., PMID:37278391

Paraneoplastic pemphigus uncovers distinct clinical and biological phenotypes of western unicentric Castleman disease., PMID:37221131

HGPRT and PNP: Recombinant Enzymes from Schistosoma mansoni and Their Role in Immunotherapy during Experimental Murine Schistosomiasis., PMID:37111413

IgM anti-MAG± peripheral neuropathy (IMAGiNe) study protocol: An international, observational, prospective registry of patients with IgM M-protein peripheral neuropathies., PMID:37041730

S2k guidelines on the management of paraneoplastic pemphigus/paraneoplastic autoimmune multiorgan syndrome initiated by the European Academy of Dermatology and Venereology (EADV)., PMID:36965110

Paraneoplastic pemphigus and Castleman's disease: a case report and a revision of the literature., PMID:36941723

Modeling in higher dimensions to improve diagnostic testing accuracy: Theory and examples for multiplex saliva-based SARS-CoV-2 antibody assays., PMID:36913381

Lupus anticoagulant laboratory diagnosis by applying the 2020 ISTH-SSC guidelines., PMID:36827954

Vitamin D and Interleukins in Chronic Rhinosinusitis with Polyposis., PMID:36742814

Subcutaneous delivery of an antibody against SARS-CoV-2 from a supramolecular hydrogel depot., PMID:36723072

Acute/subacutae demyelinating polyneuropathy in Parkinson's Disease patients on levodopa-carbidopa intestinal gel therapy: systematic review with new case report., PMID:36628506

IgG antibody response to pneumococcal-conjugated vaccine (Prevenar®13) in children with immunodeficiency disorders., PMID:36595027

Neutralizing and interfering human antibodies define the structural and mechanistic basis for antigenic diversion., PMID:36202833

Tissue proteome analysis revealed an association between cancer, immune system response, and the idiopathic granulomatous mastitis., PMID:36175807

Safety, tolerability, and immunogenicity of a 21-valent pneumococcal conjugate vaccine, V116, in healthy adults: phase 1/2, randomised, double-blind, active comparator-controlled, multicentre, US-based trial., PMID:36116461

Indirect immunofluorescence on rat bladder epithelium in patients with pemphigus vulgaris with an extended follow-up., PMID:36092265

A Case of IgG and IgA Anti-Laminin-332 Antibody-Positive Mucous Membrane Pemphigoid with IgG and IgA Anti-Envoplakin and Anti-Periplakin Antibodies., PMID:35997351

Paraneoplastic pemphigus: A detailed case series from the Netherlands revealing atypical cases., PMID:35993495

Ratiometric fluorescence immunoassay of SARS-CoV-2 nucleocapsid protein via Si-FITC nanoprobe-based inner filter effect., PMID:35992363

Injectable Nanoparticle-Based Hydrogels Enable the Safe and Effective Deployment of Immunostimulatory CD40 Agonist Antibodies., PMID:35975424

Lipid-Polymer Hybrid "Particle-in-Particle" Nanostructure Gene Delivery Platform Explored for Lyophilizable DNA and mRNA COVID-19 Vaccines., PMID:35942271

Phototherapy with Cancer-Specific Nanoporphyrin Potentiates Immunotherapy in Bladder Cancer., PMID:35921526

Paraneoplastic Pemphigus Autoantibodies Against C-terminus of Desmoplakin Induced Acantholysis In Vitro and In Vivo., PMID:35911677

Molecular mechanism of toxin neutralization in the HipBST toxin-antitoxin system of Legionella pneumophila., PMID:35882877

Clinical Patterns, Survival, Comorbidities, and Treatment Regimens in 149 Patients With Pemphigus in Tuscany (Italy): A 12-Year Hospital-Based Study., PMID:35880183

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